The Importance of Ongoing ERP Training and Support

This paper formulates and tests a model of the factors influencing organisational capacity to use an ERP system effectively in the years after go-live. Three large organisations’ post-implementation studies into end-user training were used as preliminary validation of this model; and to highlight the proposition that users’ ERP knowledge and skills will degrade in the absence of a systematic approach to ongoing training and support. The analysis also found that the negative effects of staff attrition and turnover offset the positive initiatives to enhance end-user competence in the most proactive organisation studied

The multisensory attentional consequences of tool use : a functional magnetic resonance imaging study

Background: Tool use in humans requires that multisensory information is integrated across different locations, from objects seen to be distant from the hand, but felt indirectly at the hand via the tool. We tested the hypothesis that using a simple tool to perceive vibrotactile stimuli results in the enhanced processing of visual stimuli presented at the distal, functional part of the tool. Such a finding would be consistent with a shift of spatial attention to the location where the tool is used. Methodology/Principal Findings: We tested this hypothesis by scanning healthy human participants’ brains using functional magnetic resonance imaging, while they used a simple tool to discriminate between target vibrations, accompanied by congruent or incongruent visual distractors, on the same or opposite side to the tool. The attentional hypothesis was supported: BOLD response in occipital cortex, particularly in the right hemisphere lingual gyrus, varied significantly as a function of tool position, increasing contralaterally, and decreasing ipsilaterally to the tool. Furthermore, these modulations occurred despite the fact that participants were repeatedly instructed to ignore the visual stimuli, to respond only to the vibrotactile stimuli, and to maintain visual fixation centrally. In addition, the magnitude of multisensory (visual-vibrotactile) interactions in participants’ behavioural responses significantly predicted the BOLD response in occipital cortical areas that were also modulated as a function of both visual stimulus position and tool position. Conclusions/Significance: These results show that using a simple tool to locate and to perceive vibrotactile stimuli is accompanied by a shift of spatial attention to the location where the functional part of the tool is used, resulting in enhanced processing of visual stimuli at that location, and decreased processing at other locations. This was most clearly observed in the right hemisphere lingual gyrus. Such modulations of visual processing may reflect the functional importance of visuospatial information during human tool use

Physical Activity and Academic Achievement: An Analysis of Potential Student- and School-Level Moderators

Background: Many children do not engage in sufficient physical activity, and schools provide a unique venue for children to reach their recommended 60 daily minutes of moderate-to-vigorous physical activity (MVPA). Prior research examining effects of MVPA on academic achievement is inconclusive, and few studies have investigated potential moderators of this relationship. This study examined whether student-level characteristics (gender, race/ethnicity, free/reduced-price lunch status) and school-level characteristics (proportion of students qualifying for free/reduced-price lunch, physical activity environment and opportunities) moderate the relationship between MVPA and academic achievement. Methods: In a large, diverse metropolitan public school district in Georgia, 4,936 students in Grade 4 were recruited from 40 elementary schools. Students wore accelerometers to measure school-day MVPA for a total of 15 days across three semesters (fall 2018, spring 2019, fall 2019). Academic achievement data, including course marks (grades) for math, reading, spelling, and standardized test scores in writing, math, reading, and Lexile (reading assessment), were collected at baseline (Grade 3, ages 8–9) and at follow-up in Grade 4 (ages 9–10). Standardized test scores were not measured in Grade 5 (ages 10–11) due to COVID-19-related disruptions. Multilevel modeling assessed whether student-level and/or school-level characteristics were moderators in the cross-sectional and longitudinal MVPA-academic achievement relationship. Results: Cross sectional analyses indicated that the MVPA and AA relationship was moderated only by student Hispanic ethnicity for Grade 4 fall spelling marks (β = -0.159 p \u3c 0.001). The relationship for Grade 4 fall spelling marks was also moderated by school physical activity opportunities (β = -0.128 (p \u3c 0.001). Longitudinally, there was no significant moderation of the MVPA-academic achievement. A relationship by student gender, free/reduced-price lunch status, race/ethnicity; nor for school-level factors including proportion of students qualifying for free/reduced-price lunch, physical activity environment, and physical activity opportunities. Conclusions: Overall, our results did not suggest that student- or school-level characteristics moderate the MVPA-academic achievement relationship. While statistically significant results were observed for certain outcomes, practical differences were negligible. In this population, school-based MVPA does not appear to differently affect academic performance based on student gender, race/ethnicity, free/reduced-price lunch, nor school characteristics

Genome engineering futures and the role of the Synthetic Biologist

Much of the debate surrounding the public, regulatory, IP, funding, security and ethical aspects of synthetic biology has been based on speculation about uncertain futures. This is likely to change as applications begin to emerge, but much still remains unknown. As has been seen in debates over GM crops and stem cells, interest groups and politics can play a central role in how these futures are played out, which can in turn shape scientific and technological pathways of innovation. Synthetic biologists have an important role to play in helping to influence outcomes, and it is crucial that their views and actions inform the emerging agenda. The purpose of this discussion-based workshop is to develop a number of possible future scenarios for synthetic biology. We will propose several starting points relating for example to costs of DNA synthesis, public attitudes, regulatory environments, biosafety and security, and intellectual property regimes. The focus will be on exploring interactions between factors – ethics and regulation, open source and commercial dynamics, biosecurity and militarisation – and how these may affect innovation pathways. The outcomes of the workshop will be fed back to the synthetic biology community and will ideally help to inform policy formation, as well as social science publications on synthetic biology innovation. The underlying analytical concept guiding the social science work emphasises the 'reflexivity' of synthetic biologists. This highlights the active role that they play in shaping social as well as technological genome engineering futures

Plate boundary trench retreat and dextral shear drive intracontinental fault-slip histories: Neogene dextral faulting across the Gabbs Valley and Gillis Ranges, Central Walker Lane, Nevada

The spatial-temporal evolution of intracontinental faults and the forces that drive their style, orientation, and timing are central to understanding tectonic processes. Intracontinental NW-striking dextral faults in the Gabbs Valley–Gillis Ranges (hereafter referred to as the GVGR), Nevada, define a structural domain known as the eastern Central Walker Lane located east of the western margin of the North American plate. To consider how changes in boundary type along the western margin of the North American plate influenced both the initiation and continued dextral fault slip to the present day in the GVGR, we combine our new detailed geologic mapping, structural studies, and 40Ar/39Ar geochronology with published geologic maps to calculate early to middle Miocene dextral fault-slip rates. In the GVGR, Mesozoic basement is nonconformably overlain by a late Oligocene to Miocene sequence dominated by tuffs, lavas, and sedimentary rocks. These rocks are cut and offset by four primary NW-striking dextral faults, from east to west the Petrified Spring, Benton Spring, Gumdrop Hills, and Agai Pah Hills–Indian Head faults. A range of geologic markers, including tuff- and lava-filled paleovalleys, the southern extent of lava flows, and a normal fault, show average dextral offset magnitudes of 9.6 ± 1.1 km, 7.0 ± 1.7 km, 9.7 ± 1.0 km, and 4.9 ± 1.1 km across the four faults, respectively. Cumulative dextral offset across the GVGR is 31.2 ± 2.3 km. Initiation of slip along the Petrified Spring fault is tightly bracketed between 15.99 ± 0.05 Ma and 15.71 ± 0.03 Ma, whereas slip along the other faults initiated after 24.30 ± 0.05 Ma to 20.14 ± 0.26 Ma. Assuming that slip along all four faults initiated at the same time as the Petrified Spring fault yields calculated dextral fault-slip rates of 0.4 ± 0.1–0.6 ± 0.1 mm/yr, 0.4 ± 0.1–0.5 ± 0.1 mm/yr, 0.6 ± 0.1 mm/yr, and 0.3 ± 0.1 mm/yr on the four faults, respectively. Middle Miocene initiation of dextral fault slip across the GVGR overlaps with the onset of normal slip along range-bounding faults in the western Basin and Range to the north and the northern Eastern California shear zone to the south. Based on this spatial-temporal relationship, we propose that dextral fault slip across the GVGR defines a kinematic link or accommodation zone between the two regions of extension. At the time of initiation of dextral slip across the GVGR, the plate-boundary setting to the west was characterized by subduction of the Farallon plate beneath the North American plate. To account for the middle Miocene onset of extension across the Basin and Range and dextral slip in the GVGR, we hypothesize that middle Miocene trench retreat drove westward motion of the Sierra Nevada and behind it, crustal extension across the Basin and Range and NW-dextral shear within the GVGR. During the Pliocene, the plate boundary to the west changed to NW-dextral shear between the Pacific and North American plates, which drove continued dextral slip along the same faults within the GVGR because they were fortuitously aligned subparallel to plate boundary motion

Paleomagnetic Results from the Snake River Plain: Contribution to the Time-Averaged Field Global Database

This study presents paleomagnetic results from the Snake River Plain (SRP) in southern Idaho as a contribution to the time-averaged field global database. Paleomagnetic samples were measured from 26 sites, 23 of which ( 13 normal, 10 reverse) yielded site mean directions meeting our criteria for acceptable paleomagnetic data. Flow ages (on 21 sites) range from 5 ka to 5.6 Ma on the basis of Ar-40/Ar-39 dating methods. The age and polarity for the 21 dated sites are consistent with the Geomagnetic Reversal Time Scale except for a single reversely magnetized site dated at 0.39 Ma. This is apparently the first documented excursion associated with a period of low paleointensity detected in both sedimentary and igneous records. Combining the new data from the SRP with data published from the northwest United States between the latitudes of 40degrees and 50degreesN, there are 183 sites in all that meet minimum acceptability criteria for legacy and new data. The overall mean direction of 173 normally magnetized sites has a declination of 2.3degrees, inclination of 61.4degrees, a Fisher concentration parameter (kappa) of 58, and a radius of 95% confidence (alpha(95)) of 1.4degrees. Reverse sites have a mean direction of 182.4degrees declination, -58.6degrees inclination, kappa of 50, and alpha(95) of 6.9degrees. Normal and reversed mean directions are antipodal and indistinguishable from a geocentric axial dipole field at the 95% confidence level. Virtual geomagnetic pole dispersion was found to be circularly symmetric, while the directional data were elongate north-south. An updated and corrected database for the northwestern U. S. region has been contributed to the Magnetics Information Consortium (MagIC) database at http://earthref.org