Constraints on present-day Basin and Range deformation from space geodesy

We use new space geodetic data from very long baseline interferometry and satellite laser ranging combined with other geodetic and geologic data to study contemporary deformation in the Basin and Range province of the western United States. Northwest motion of the central Sierra Nevada block relative to stable North America, a measure of integrated Basin and Range deformation, is 12.1±1.2 mm/yr oriented N38°W±5° (one standard error), in agreement with previous geological estimates within uncertainties. This velocity reflects both east-west extension concentrated in the eastern Basin and Range and north-northwest directed right lateral shear concentrated in the western Basin and Range. Ely, Nevada is moving west at 4.9±1.3 mm/yr relative to stable North America, consistent with dip-slip motion on the north striking Wasatch fault and other north striking normal faults. Comparison with ground-based geodetic data suggests that most of this motion is accommodated within ∼50 km of the Wasatch fault zone. Paleoseismic data for the Wasatch fault zone and slip rates based on seismic energy release in the region both suggest much lower slip rates. The discrepancy may be explained by some combination of additional deformation away from the Wasatch fault itself, aseismic slip, or a seismic rate that is anomalously low with respect to longer time averages. Deformation in the western Basin and Range province is also largely confined to a relatively narrow boundary zone and in our study area is partitioned into the eastern California shear zone, accommodating 10.7±1.6 mm/yr of north-northwest directed right-lateral shear, and a small component (∼1 mm/yr) of west-southwest - east-northeast extension. A slip rate budget for major strike-slip faults in our study area based on a combination of local geodetic or late Quaternary geologic data and the regional space geodetic data suggests the following rates of right-lateral slip: Owens Valley fault zone, 3.9±1.1 mm/yr; Death Valley-Furnace Creek fault zone, 3.3±2.2 mm/yr; White Mountains fault zone in northern Owens Valley, 3.4±1.2 mm/yr; Fish Lake Valley fault zone, 6.2±2.3 mm/yr. In the last few million years the locus of right-lateral shear in the region has shifted west and become more north trending as slip on the northwest striking Death Valley-Furnace Creek fault zone has decreased and is increasingly accommodated on the north-northwest striking Owens Valley fault zone

The present-day number of tectonic plates

The number of tectonic plates on Earth described in the literature has expanded greatly since the start of the plate tectonic era, when only about a dozen plates were considered in global models of present-day plate motions. With new techniques of more accurate earthquake epicenter locations, modern ways of measuring ocean bathymetry using swath mapping, and the use of space based geodetic techniques, there has been a huge growth in the number of plates thought to exist. The study by Bird (2003) proposed 52 plates, many of which were delineated on the basis of earthquake locations. Because of the pattern of areas of these plates, he suggested that there should be more small plates than he could identify. In this paper, I gather together publications that have proposed a total of 107 new plates, giving 159 plates in all. The largest plate (Pacific) is about 20 % of the Earth's area or 104 Mm (super 2) , and the smallest of which (Plate number 5 from Hammond et al. 2011) is only 273 km (super 2) in area. Sorting the plates by size allows us to investigate how size varies as a function of order. There are several changes of slope in the plots of plate number organized by size against plate size order which are discussed. The sizes of the largest seven plates is constrained by the area of the Earth. A middle set of 73 plates down to an area of 97,563 km (super 2) (the Danakil plate at number 80, is the plate of median size) follows a fairly regular pattern of plate size as a function of plate number. For smaller plates, there is a break in the slope of the plate size/plate number plot and the next 32 plates follow a pattern of plate size proposed by the models of Koehn et al. (2008) down to an area of 11,638 km (super 2) (West Mojave plate # 112). Smaller plates do not follow any regular pattern of area as a function of plate number, probably because we have not sampled enough of these very small plates to reveal any clear pattern. Copyright 2016 The Author(s) and Harrison

Renal metabolism of C-peptide in patients with early insulin-dependent diabetes mellitus

Renal metabolism of C-peptide was studied in 6 patients with early insulin-dependent diabetes mellitus (IDDM) with residual beta cell activity and in 11 nondiabetic subjects by the arterial-venous difference technique both in the postabsorptive state and for 80 min after ingestion of an amino acid mixture (0.8 g/kg). Urinary C-peptide (Cp) excretion, glomerular filtration rate and renal plasma flow were also measured. In the postabsorptive state in IDDM, renal uptake of Cp is reduced, while its urinary excretion and clearance are significantly increased. As a result, net renal extraction is markedly reduced. In contrast to controls, renal uptake and net extraction of C-peptide after amino acid ingestion do not increase in patients; the peritubular uptake evident in normal subjects is not detectable. Urinary excretion and clearance of Cp remain significantly higher in IDDM patients. In both groups, renal uptake of C-peptide is directly related to its renal load: however, in IDDM, the increase in Cp uptake for each increment in renal load is 35% lower than in controls (p < 0.001). Furthermore, as opposed to controls, urinary Cp excretion is not correlated with its arterial levels. Therefore IDDM patients have marked defects in renal handling of endogenous Cp, regarding both the amount metabolized by renal tissue and that reabsorbed by tubular cells. These data indicate an early alteration in the diabetic kidney that also impairs the reliability of urinary Cp evaluation as an index of residual beta cell activity in IDDM patient

Renal metabolism of C-peptide in patients with early insulin-dependent diabetes mellitus

Renal metabolism of C-peptide was studied in 6 patients with early insulin-dependent diabetes mellitus (IDDM) with residual beta cell activity and in 11 nondiabetic subjects by the arterial-venous difference technique both in the postabsorptive state and for 80 min after ingestion of an amino acid mixture (0.8 g/kg). Urinary C-peptide (Cp) excretion, glomerular filtration rate and renal plasma flow were also measured. In the postabsorptive state in IDDM, renal uptake of Cp is reduced, while its urinary excretion and clearance are significantly increased. As a result, net renal extraction is markedly reduced. In contrast to controls, renal uptake and net extraction of C-peptide after amino acid ingestion do not increase in patients; the peritubular uptake evident in normal subjects is not detectable. Urinary excretion and clearance of Cp remain significantly higher in IDDM patients. In both groups, renal uptake of C-peptide is directly related to its renal load: however, in IDDM, the increase in Cp uptake for each increment in renal load is 35% lower than in controls (p < 0.001). Furthermore, as opposed to controls, urinary Cp excretion is not correlated with its arterial levels. Therefore IDDM patients have marked defects in renal handling of endogenous Cp, regarding both the amount metabolized by renal tissue and that reabsorbed by tubular cells. These data indicate an early alteration in the diabetic kidney that also impairs the reliability of urinary Cp evaluation as an index of residual beta cell activity in IDDM patients