1,411 research outputs found
Juegos catequísticos
Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2009-201
Optical constants of solid methane
Methane is the most abundant simple organic molecule in the outer solar system bodies. In addition to being a gaseous constituent of the atmospheres of the Jovian planets and Titan, it is present in the solid form as a constituent of icy surfaces such as those of Triton and Pluto, and as cloud condensate in the atmospheres of Titan, Uranus, and Neptune. It is expected in the liquid form as a constituent of the ocean of Titan. Cometary ices also contain solid methane. The optical constants for both solid and liquid phases of CH4 for a wide temperature range are needed for radiative transfer calculations, for studies of reflection from surfaces, and for modeling of emission in the far infrared and microwave regions. The astronomically important visual to near infrared measurements of solid methane optical constants are conspicuously absent from the literature. Preliminary results are presented on the optical constants of solid methane for the 0.4 to 2.6 micrometer region. Deposition onto a substrate at 10 K produces glassy (semi-amorphous) material. Annealing this material at approximately 33 K for approximately 1 hour results in a crystalline material as seen by sharper, more structured bands and negligible background extinction due to scattering. The constant k is reported for both the amorphous and the crystalline (annealed) states. Typical values (at absorption maxima) are in the .001 to .0001 range. Below lambda = 1.1 micrometers the bands are too weak to be detected by transmission through the films less than or equal to 215 micrometers in thickness, employed in the studies to date. Using previously measured values of the real part of the refractive index, n, of liquid methane at 110 K, n is computed for solid methane using the Lorentz-Lorenz relationship. Work is in progress to extend the measurements of optical constants n and k for liquid and solid to both shorter and longer wavelengths, eventually providing a complete optical constants database for condensed CH4
Is the black-widow pulsar PSR J1555-2908 in a hierarchical triple system?
The 559 Hz black-widow pulsar PSR J1555-2908, originally discovered in radio, is also a bright gamma-ray pulsar. Timing its pulsations using 12 yr of Fermi-LAT gamma-ray data reveals long-term variations in its spin frequency that are much larger than is observed from other millisecond pulsars. While this variability in the pulsar rotation rate could be intrinsic "timing noise", here we consider an alternative explanation: the variations arise from the presence of a very-low-mass third object in a wide multi-year orbit around the neutron star and its low-mass companion. With current data, this hierarchical-triple-system model describes the pulsar's rotation slightly more accurately than the best-fitting timing-noise model. Future observations will show if this alternative explanation is correct
Predictors of disease severity in children presenting from the community with febrile illnesses: a systematic review of prognostic studies.
Early identification of children at risk of severe febrile illness can optimise referral, admission and treatment decisions, particularly in resource-limited settings. We aimed to identify prognostic clinical and laboratory factors that predict progression to severe disease in febrile children presenting from the community.
We systematically reviewed publications retrieved from MEDLINE, Web of Science and Embase between 31 May 1999 and 30 April 2020, supplemented by hand search of reference lists and consultation with an expert Technical Advisory Panel. Studies evaluating prognostic factors or clinical prediction models in children presenting from the community with febrile illnesses were eligible. The primary outcome was any objective measure of disease severity ascertained within 30 days of enrolment. We calculated unadjusted likelihood ratios (LRs) for comparison of prognostic factors, and compared clinical prediction models using the area under the receiver operating characteristic curves (AUROCs). Risk of bias and applicability of studies were assessed using the Prediction Model Risk of Bias Assessment Tool and the Quality In Prognosis Studies tool.
Of 5949 articles identified, 18 studies evaluating 200 prognostic factors and 25 clinical prediction models in 24 530 children were included. Heterogeneity between studies precluded formal meta-analysis. Malnutrition (positive LR range 1.56-11.13), hypoxia (2.10-8.11), altered consciousness (1.24-14.02), and markers of acidosis (1.36-7.71) and poor peripheral perfusion (1.78-17.38) were the most common predictors of severe disease. Clinical prediction model performance varied widely (AUROC range 0.49-0.97). Concerns regarding applicability were identified and most studies were at high risk of bias.
Few studies address this important public health question. We identified prognostic factors from a wide range of geographic contexts that can help clinicians assess febrile children at risk of progressing to severe disease. Multicentre studies that include outpatients are required to explore generalisability and develop data-driven tools to support patient prioritisation and triage at the community level.
CRD42019140542
Should all acutely ill children in primary care be tested with point-of-care CRP: A cluster randomised trial
Background: Point-of-care blood C-reactive protein (CRP) testing has diagnostic value in helping clinicians rule out the possibility of serious infection. We investigated whether it should be offered to all acutely ill children in primary care or restricted to those identified as at risk on clinical assessment. Methods: Cluster randomised controlled trial involving acutely ill children presenting to 133 general practitioners (GPs) at 78 GP practices in Belgium. Practices were randomised to undertake point-of-care CRP testing in all children (1730 episodes) or restricted to children identified as at clinical risk (1417 episodes). Clinical risk was assessed by a validated clinical decision rule (presence of one of breathlessness, temperature ≥ 40 °C, diarrhoea and age 12-30 months, or clinician concern). The main trial outcome was hospital admission with serious infection within 5 days. No specific guidance was given to GPs on interpreting CRP levels but diagnostic performance is reported at 5, 20, 80 and 200 mg/L. Results: Restricting CRP testing to those identified as at clinical risk substantially reduced the number of children tested by 79.9 % (95 % CI, 77.8-82.0 %). There was no significant difference between arms in the number of children with serious infection who were referred to hospital immediately (0.16 % vs. 0.14 %, P = 0.88). Only one child with a CRP < 5 mg/L had an illness requiring admission (a child with viral gastroenteritis admitted for rehydration). However, of the 80 children referred to hospital to rule out serious infection, 24 (30.7 %, 95 % CI, 19.6-45.6 %) had a CRP < 5 mg/L. Conclusions: CRP testing should be restricted to children at higher risk after clinical assessment. A CRP < 5 mg/L rules out serious infection and could be used by GPs to avoid unnecessary hospital referrals
Report of the GDR working group on the R-parity violation
This report summarizes the work of the "R-parity violation group" of the
French Research Network (GDR) in Supersymmetry, concerning the physics of
supersymmetric models without conservation of R-parity at HERA, LEP, Tevatron
and LHC and limits on R-parity violating couplings from various processes. The
report includes a discussion of the recent searches at the HERA experiment,
prospects for new experiments, a review of the existing limits, and also
theoretically motivated alternatives to R-parity and a brief discussion on the
implications of R-parity violation on the neutrino masses.Comment: 60 pages, LaTeX, 22 figures, 2 table
Mrk 421, Mrk 501, and 1ES 1426+428 at 100 GeV with the CELESTE Cherenkov Telescope
We have measured the gamma-ray fluxes of the blazars Mrk 421 and Mrk 501 in
the energy range between 50 and 350 GeV (1.2 to 8.3 x 10^25 Hz). The detector,
called CELESTE, used first 40, then 53 heliostats of the former solar facility
"Themis" in the French Pyrenees to collect Cherenkov light generated in
atmospheric particle cascades. The signal from Mrk 421 is often strong. We
compare its flux with previously published multi-wavelength studies and infer
that we are straddling the high energy peak of the spectral energy
distribution. The signal from Mrk 501 in 2000 was weak (3.4 sigma). We obtain
an upper limit on the flux from 1ES 1426+428 of less than half that of the Crab
flux near 100 GeV. The data analysis and understanding of systematic biases
have improved compared to previous work, increasing the detector's sensitivity.Comment: 15 pages, 14 figures, accepted to A&A (July 2006) August 19 --
corrected error in author lis
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