1,500 research outputs found
Wind tunnel investigation of the effect of high relative velocities on the structural integrity of birds
An experimental investigation was conducted in a supersonic wind tunnel to determine the effect a sudden high velocity headwind had on the physical deformation and structural breakup characteristics of birds. Several sizes of recently killed birds were dropped into the test section at free-stream Mach numbers ranging from 0.2 to 0.8 and photographed with high-speed motion-picture cameras. These conditions simulated flow conditions encountered when birds are ingested into the inlets of high speed aircraft, thereby constituting a safety hazard to the aircraft and its occupants. The investigation shows that, over the range of headwind conditions tested, the birds remained structurally intact and did not suffer any appreciable deformation or structural breakup
Refan program. Phase 1: Summary report
The Refan Program is aimed at a large reduction in aircraft approach and takeoff noise in the vicinity of airports caused by the JT3D-powered 707's and DC-8's and the JT8D-powered 727's, 737's and DC-9's. These aircraft represent a major part of the existing commercial fleet. The noise reductions can be achieved by engine and nacelle modifications in the form of aircraft retrofit kits. Engine turbomachinery noise is reduced by replacing the current two-stage fan with a larger single-stage fan and by nacelle acoustic treatment. Jet noise is reduced by the reduction on jet velocity caused by additional turbine work extraction to drive the larger bypass fan. The predicted net effect of these modifications on installed performance is large noise reductions on both approach and takeoff, increased takeoff thrust, decreased takeoff field length, and maintained or improved aircraft range depending on the amount of acoustic treatment included. The Refan Program is being conducted in two phases under contracts with one engine and two airframe companies. Results of the Phase I work are summarized in this report which describes the refan nacelle configurations studied, the airplane modifications required to install the nacelles, and the resulting airplane performance and noise reductions predicted for all five aircraft
NASA Quiet Clean General Aviation Turbofan (QCGAT) program status
The suitability of large engine technology to reduce noise, emissions, and fuel consumption of small turbine engines and develop new technology where required is determined. The design, fabrication, assembly, test, and delivery of the experimental engines to NASA are discussed
Vertical Integration and Market Structure
Contractual theories of vertical integration derive firm boundaries as an efficient response to market transaction costs. These theories predict a relationship between underlying features of transactions and observed integration decisions. There has been some progress in testing these predictions, but less progress in quantifying their importance. One difficulty is that empirical applications often must consider firm structure together with industry structure. Research in industrial organization frequently has adopted this perspective, emphasizing how scale and scope economies, and strategic considerations, influence patterns of industry integration. But this research has paid less attention to contractual or organizational details, so that these two major lines of research on vertical integration have proceeded in parallel with only rare intersection. We discuss the value of combining different viewpoints from organizational economics and industrial organization.
Performance of an aerodynamically positioned auxiliary inlet ejector nozzle at Mach numbers from 0 to 2.0
Performance of aerodynamically positioned auxiliary inlet ejector nozzle at Mach numbers from 0 to 2.
Wheat productivity estimates using LANDSAT data
The author has identified the following significant results. Large area LANDSAT yield estimates were generated. These results were compared with estimates computed using a meteorological yield model (CCEA). Both of these estimates were compared with Kansas Crop and Livestock Reporting Service (KCLRS) estimates of yield, in an attempt to assess the relative and absolute accuracy of the LANDSAT and CCEA estimates. Results were inconclusive. A large area direct wheat prediction procedure was implemented. Initial results have produced a wheat production estimate comparable with the KCLRS estimate
Aerobic Exercise Attenuates Risk of Coronary Artery Disease and Improves Mobility in SCI
Please see the pdf version of the abstract
AMPA Receptor Phosphorylation and Synaptic Colocalization on Motor Neurons Drive Maladaptive Plasticity below Complete Spinal Cord Injury.
Clinical spinal cord injury (SCI) is accompanied by comorbid peripheral injury in 47% of patients. Human and animal modeling data have shown that painful peripheral injuries undermine long-term recovery of locomotion through unknown mechanisms. Peripheral nociceptive stimuli induce maladaptive synaptic plasticity in dorsal horn sensory systems through AMPA receptor (AMPAR) phosphorylation and trafficking to synapses. Here we test whether ventral horn motor neurons in rats demonstrate similar experience-dependent maladaptive plasticity below a complete SCI in vivo. Quantitative biochemistry demonstrated that intermittent nociceptive stimulation (INS) rapidly and selectively increases AMPAR subunit GluA1 serine 831 phosphorylation and localization to synapses in the injured spinal cord, while reducing synaptic GluA2. These changes predict motor dysfunction in the absence of cell death signaling, suggesting an opportunity for therapeutic reversal. Automated confocal time-course analysis of lumbar ventral horn motor neurons confirmed a time-dependent increase in synaptic GluA1 with concurrent decrease in synaptic GluA2. Optical fractionation of neuronal plasma membranes revealed GluA2 removal from extrasynaptic sites on motor neurons early after INS followed by removal from synapses 2 h later. As GluA2-lacking AMPARs are canonical calcium-permeable AMPARs (CP-AMPARs), their stimulus- and time-dependent insertion provides a therapeutic target for limiting calcium-dependent dynamic maladaptive plasticity after SCI. Confirming this, a selective CP-AMPAR antagonist protected against INS-induced maladaptive spinal plasticity, restoring adaptive motor responses on a sensorimotor spinal training task. These findings highlight the critical involvement of AMPARs in experience-dependent spinal cord plasticity after injury and provide a pharmacologically targetable synaptic mechanism by which early postinjury experience shapes motor plasticity
Restenosis after directional coronary atherectomy: Differences between primary atheromatoes and restenosls lesions and influence of subintimal tissue resection
AbstractRates of restenosis were evaluated in 70 patients (74 lesions) after successful directional coronary atherectomy. The extent of vascular tissue resection was correlated with restenosis rates for coronary (n = 59) and vein bypass graft (n = 15) lesions.After 6 months, the overall restenosis rate was 50% (37 of 74 lesions); it was 42% (15 of 36 lesions) when intima alone was resected, 50% (7 of 14 lesions) when media was resected and 63% (15 of 24 lesions) when adventitia was resected. Subintimal tissue resection increased the restenosis rate for vein grafts (43% with intimal resection versus 100% with subintimal resection, p = 0.01) but not for coronary arteries (50% versus 48%). There was no overall difference in restenosis rates after atherectomy between primary lesions and restenosis lesions that occurred after balloon angioplasty (46% versus 54%). Among postballoon angioplasty restenosis lesions, a higher rate of restenosis after atherectomy was found with subintimal than with intimal resection (78% versus 32%, p = 0.01).Tissues from patients undergoing a second atherectomy for restenosis after initial atherectomy (n = 8) demonstrated neointimal hyperplasia that appeared histotogically identical to restenotic tissue developing after balloon angioplasty (n = 37).These data suggest that the cellular response to directional coronary atherectomy is characterized by neointimal proliferation similar to that which may develop after balloon angioplasty. The extent of fibrous hyperplasia appears to be related to the depth of tissue resection in vein graft lesions and coronary artery restenosis lesions that occur after balloon angioplasty but not in primary atheromatous coronary artery lesions
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