Two-View Geometry Scoring Without Correspondences

Camera pose estimation for two-view geometry traditionally relies on RANSAC. Normally, a multitude of image correspondences leads to a pool of proposed hypotheses, which are then scored to find a winning model. The inlier count is generally regarded as a reliable indicator of "consensus". We examine this scoring heuristic, and find that it favors disappointing models under certain circumstances. As a remedy, we propose the Fundamental Scoring Network (FSNet), which infers a score for a pair of overlapping images and any proposed fundamental matrix. It does not rely on sparse correspondences, but rather embodies a two-view geometry model through an epipolar attention mechanism that predicts the pose error of the two images. FSNet can be incorporated into traditional RANSAC loops. We evaluate FSNet on fundamental and essential matrix estimation on indoor and outdoor datasets, and establish that FSNet can successfully identify good poses for pairs of images with few or unreliable correspondences. Besides, we show that naively combining FSNet with MAGSAC++ scoring approach achieves state of the art results

The LCLS-II Photoinjector Laser Infrastructure

This paper presents a comprehensive technical overview of the Linac Coherent Light Source II (LCLS-II) photoinjector laser system, its first and foremost component. The LCLS-II photoinjector laser system serves as an upgrade to the original LCLS at SLAC National Accelerator Laboratory. This advanced laser system generates high-quality laser beams to power the LCLS-II, contributing to the instrument's unprecedented brightness, precision, and flexibility. Our discussion extends to the various subsystems that comprise the photoinjector, including the photocathode laser, laser heater, and beam transport systems. Lastly, we draw attention to the ongoing research and development infrastructure underway to enhance the functionality and efficiency of the LCLS-II, and similar X-ray free-electron laser facilities around the world, thereby contributing to the future of laser technology and its applications.Comment: Submitted to High Power Laser Science and Engineerin

H3 Lysine 4 Is Acetylated at Active Gene Promoters and Is Regulated by H3 Lysine 4 Methylation

Methylation of histone H3 lysine 4 (H3K4me) is an evolutionarily conserved modification whose role in the regulation of gene expression has been extensively studied. In contrast, the function of H3K4 acetylation (H3K4ac) has received little attention because of a lack of tools to separate its function from that of H3K4me. Here we show that, in addition to being methylated, H3K4 is also acetylated in budding yeast. Genetic studies reveal that the histone acetyltransferases (HATs) Gcn5 and Rtt109 contribute to H3K4 acetylation in vivo. Whilst removal of H3K4ac from euchromatin mainly requires the histone deacetylase (HDAC) Hst1, Sir2 is needed for H3K4 deacetylation in heterochomatin. Using genome-wide chromatin immunoprecipitation (ChIP), we show that H3K4ac is enriched at promoters of actively transcribed genes and located just upstream of H3K4 tri-methylation (H3K4me3), a pattern that has been conserved in human cells. We find that the Set1-containing complex (COMPASS), which promotes H3K4me2 and -me3, also serves to limit the abundance of H3K4ac at gene promoters. In addition, we identify a group of genes that have high levels of H3K4ac in their promoters and are inadequately expressed in H3-K4R, but not in set1Δ mutant strains, suggesting that H3K4ac plays a positive role in transcription. Our results reveal a novel regulatory feature of promoter-proximal chromatin, involving mutually exclusive histone modifications of the same histone residue (H3K4ac and H3K4me)

Femtosecond Operation of the LCLS for User Experiments

In addition to its normal operation at 250pC, the LCLS has operated with 20pC bunches delivering X-ray beams to users with energies between 800eV and 2 keV and with bunch lengths below 10 fs FWHM. A bunch arrival time monitor and timing transmission system provide users with sub 50 fs synchronization between a laser and the X-rays for pump/probe experiments. We describe the performance and operational experience of the LCLS for short bunch experiments