9 research outputs found
Akut cardiovascularis kórképek vizsgálata különböző légköri paraméterek tükrében
Introduction: Research on the effects of meteorological parameters on cardiovascular diseases may allow the development of novel prevention strategies.
Aim: The aim of the authors was to examine the correlation between meteorological parameters and the occurrence of acute cardiovascular diseases.
Method: A retrospective analysis was performed in 343 patients diagnosed with acute cardiovascular disease and treated at the Department of Vascular Surgery, Semmelweis University in 2010.
Results: Acute cardiovascular diseases showed a seasonal variation with the highest occurrence in winter months (p = 0.0001). The daily increase of the events (n ≥ 3) were associated with front movements days (in 62.5% of cases). A significant correlation was found between the intraday temperature difference (p<0.0001), the intraday atmospheric pressure difference (p = 0.0034), the lowest maximum daily temperature (p<0.0001) and the occurrence of acute cardiovascular diseases. During the days with front movements 64% of the patients were older than 66 years of age. Among risk factors, hypertension showed front sensitivity.
Conclusions: Meteorological parameters are minor risk factors in the occurrence of acute cardiovascular diseases
Az orvosmeteorolĂłgia törtĂ©neti áttekintĂ©se – Ăşj horizont a preventĂv medicina terĂĽletĂ©n
Abstract: The aim of this article is to draw attention to the medical meteorology from the perspective of the history of science. Unfortunately medical meteorology is not part of the daily medical practice. The climate change is a new challenge for health care worldwide. It concerns millions of people a higher morbidity and mortality rate. Knowing the effects of the meteorological parameters as risk factors can allow us to create new prevention strategies. These new strategies could help to decrease the negative health effects of the meteorological parameters. Nowadays on the field of the medical prevention the medical meteorology is a new horizon and in the future it could play an important role. Health care professionals have the most important role to fight against the negative effects of the global climate change. Orv. Hetil., 2017, 158(5), 187?191
Complex effects of atmospheric parameters on acute cardiovascular diseases and major cardiovascular risk factors: data from the CardiometeorologySM study
Abstract Several studies have examined the cardiovascular effects of atmospheric parameters as separate factors; however, few have investigated atmospheric parameters’ joint effects. We aim to explore the joint effects of atmospheric parameters on acute cardiovascular diseases (ACVDs) and on major cardiovascular risk factors (CRFs). We correlated all ACVD admissions with major CRFs and local atmospheric conditions during a 5-year study period. A seasonal variation was detected in a higher incidence rate during cold atmospheric conditions. There were significant incidence relative ratios, including: 1.140 (95% CI [1.020, 1.283]) for daily temperature change (≥5 °C); 0.991 (95% CI [0.988, 0.994]) for average daily temperature; and 1.290 (95% CI [1.090, 1.599]) for the interaction of daily temperature change (≥5 °C) with humidity change (≥40%). We observed a significant association between the atmospheric parameters’ joint effects and hyperlipidaemia, diabetes, and previous ACVDs. Patients with diabetes had the highest significant incidence relative ratio at 2.429 (95% CI [1.088, 5.424]) for humidity-temperature interactions. Thus, the atmospheric parameters’ joint effects play an important role as minor CRFs. These unfavourable atmospheric situations are predicted to increase the number of ACVDs mainly. Our study may help to organize prevention strategies more effectively and to reduce cardiovascular risks
A cardiogen thromboembolia kockázati tényezője: légköri paraméterek hatása korunk "cardiovascularis járványára", a pitvarfibrillációra
BevezetĂ©s: A pitvarfibrilláciĂł korunk "cardiovascularis járványa", a leggyakoribb tartĂłs arrythmia, mely a cardiogen thromboembolia kialakulásának kockázatát ötszörösĂ©re emeli. Napjainkban, az egyre inkább öregedĹ‘ társadalom következmĂ©nyekĂ©nt, a pitvarfibrilláciĂł incidenciája Ă©s prevalenciája nĹ‘, Ă©s további emelkedĂ©s várhatĂł. EbbĹ‘l következik, hogy a pitvarfibrilláciĂłs kutatások egyre nagyobb nĂ©pegĂ©szsĂ©gĂĽgyi jelentĹ‘sĂ©ggel bĂrnak. CĂ©lkitűzĂ©s: Jelen kutatás a frontok Ă©s kĂĽlönbözĹ‘ meteorolĂłgiai paramĂ©terek pitvarfibrilláciĂłt kiváltĂł hatását vizsgálja. MĂłdszer: A Semmelweis Egyetem Városmajori SzĂv- Ă©s ÉrgyĂłgyászati Klinikán, 2007-2013 közötti idĹ‘tartamában, akut pitvarfibrilláciĂłval kezelt betegek esetszám gyakoriságának Ă©s klinikopatholĂłgiai jellemzĹ‘inek retrospektĂv vizsgálata, valamint meteorolĂłgiai paramĂ©terekkel valĂł összefĂĽggĂ©sĂ©nek elemzĂ©se törtĂ©nt. EredmĂ©nyek: Az akut pitvarfibrilláciĂł incidenciája szĂ©lsĹ‘sĂ©ges meteorolĂłgiai tĂ©nyezĹ‘k fennállása során emelkedĹ‘ tendenciát mutat. A napi hĹ‘mĂ©rsĂ©klet ingadozása, illetve a napi lĂ©gköri nyomás alakulása nem befolyásolja az akut pitvarfibrilláciĂłs esetszámot, viszont magas relatĂv páratartalom esetĂ©n a kĂłrkĂ©p fellĂ©pĂ©se figyelhetĹ‘ meg. A fronthatások Ă©s az akut pitvarfibrilláciĂł incidenciája között erĹ‘sen szignifikáns korreláciĂł mutathatĂł ki. Nemek szerinti front-szenzitivitási vizsgálatban a fĂ©rfiak meteoropata tulajdonságokat mutattak. Az akut esetek 56%-a hidegfronthatás alatt alakult ki. A vizsgált major cardiovascularis rizikĂłtĂ©nyezĹ‘k (hypertonia, diabetes, hyperlipidaemia, elĹ‘zĹ‘ cardiovascularis megbetegedĂ©s) jelentĹ‘sen frontĂ©rzĂ©kenyek. Az akut pitvarfibrilláciĂłk incidenciája erĹ‘sen szignifikáns összefĂĽggĂ©st mutat a napi szĂ©lmaximum Beaufort-fokozatával. A koreloszlást tekintve a vizsgált betegek 56%-a 66 Ă©v feletti. KövetkeztetĂ©sek: A kĂĽlönbözĹ‘ meteorolĂłgiai paramĂ©terek trigger faktorkĂ©nt fokozzák az akut pitvarfibrilláciĂł kialakulását. A kĂĽlönbözĹ‘ lĂ©gköri paramĂ©terek minor cardialis rizikĂłtĂ©nyezĹ‘nek tekinthetĹ‘k
Akut cardiovascularis kórképek vizsgálata különböző légköri paraméterek tükrében | Occurrence of acute cardiovascular diseases under different atmospheric parameters
BevezetĂ©s: A meteorolĂłgiai paramĂ©terek cardiovascularis betegsĂ©gekre gyakorolt hatásának kutatása Ăşj prevenciĂłs stratĂ©giák kialakulását teszi lehetĹ‘vĂ©. CĂ©lkitűzĂ©s: A szerzĹ‘k a meteorolĂłgiai paramĂ©terek Ă©s az akut cardiovascularis betegsĂ©gek elĹ‘fordulási kapcsolatának elemzĂ©sĂ©t tűztĂ©k ki cĂ©lul. MĂłdszer: RetrospektĂv vizsgálatban a Semmelweis Egyetem, ÉrsebĂ©szeti Klinikán 2010-ben kezelt betegek (n = 343) klinikopatolĂłgiai jellemzĹ‘it Ă©s esetszám-elĹ‘fordulási arányát elemeztĂ©k lĂ©gköri paramĂ©terhatásokkal valĂł összefĂĽggĂ©sben. EredmĂ©nyek: A kĂłrkĂ©pek elĹ‘fordulásában szezonális variabilitást Ă©szleltek (p = 0,0001), tĂ©li esetszám-emelkedĂ©ssel. Napi esetszám-emelkedĂ©s (n≥3) 62,5%-ban fronthatással bĂrĂł napokon fordult elĹ‘. Szignifikáns korreláciĂł volt kimutathatĂł a napi hĹ‘mĂ©rsĂ©klet-ingadozás (p<0,0001), a napi lĂ©gköri nyomásingadozás (p = 0,0034), illetve az alacsony napi maximum-hĹ‘mĂ©rsĂ©klet (p<0,0001) Ă©s az akut cardiovascularis betegsĂ©gek elĹ‘fordulási aránya között. Fronthatással bĂrĂł napokon a 66 Ă©ves Ă©letkor feletti betegarány nagyobb volt (64%). A kockázati tĂ©nyezĹ‘k közĂĽl a hypertonia mutatott frontĂ©rzĂ©kenysĂ©get. KövetkeztetĂ©sek: A meteorolĂłgiai paramĂ©terek minor kockázati tĂ©nyezĹ‘nek tekinthetĹ‘k az akut cardiovascularis megbetegedĂ©sek kialakulásában. Orv. Hetil., 2014, 155(27), 1078–1082.
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Introduction: Research on the effects of meteorological parameters on cardiovascular diseases may allow the development of novel prevention strategies. Aim: The aim of the authors was to examine the correlation between meteorological parameters and the occurrence of acute cardiovascular diseases. Method: A retrospective analysis was performed in 343 patients diagnosed with acute cardiovascular disease and treated at the Department of Vascular Surgery, Semmelweis University in 2010. Results: Acute cardiovascular diseases showed a seasonal variation with the highest occurrence in winter months (p = 0.0001). The daily increase of the events (n≥3) were associated with front movements days (in 62.5% of cases). A significant correlation was found between the intraday temperature difference (p<0.0001), the intraday atmospheric pressure difference (p = 0.0034), the lowest maximum daily temperature (p<0.0001) and the occurrence of acute cardiovascular diseases. During the days with front movements 64% of the patients were older than 66 years of age. Among risk factors, hypertension showed front sensitivity. Conclusions: Meteorological parameters are minor risk factors in the occurrence of acute cardiovascular diseases. Orv. Hetil., 2014, 155(27), 1078–1082
Ateroszklerotikus és egyéb artériás szövődmények daganatos megbetegedésekben
A 21. századot antropogenikus korként lehet meghatározni, amelyben az ipari forradalom gazdasági fellendülést okozó
hatása mellett a sĂşlyos krĂłnikus betegsĂ©gek elĹ‘fordulási aránya is növekedett (környezeti Ă©s egĂ©szsĂ©gĂĽgyi károsĂtĂł
tényezők miatt). Korunk legelterjedtebb népegészségügyi terhei közé tartozó, világszerte vezető mortalitási ténye-
zĹ‘nek számĂtĂł krĂłnikus betegsĂ©gcsoportba tartoznak a daganatos elváltozások, az ateroszklerĂłzis, Ă©s az artĂ©riás
megbetegedések. Az egyre hatékonyabb kezelési lehetőségeknek köszönhetően a daganatos betegségek túlélési
rátája mindinkább javul, jelenleg megközelĂtĹ‘en 12 milliĂł daganatos betegsĂ©get tĂşlĂ©lĹ‘ egyĂ©n Ă©l EurĂłpában. Minde-
mellett Ă©vente, világszerte közel 17,9 milliĂł a szĂv- Ă©s Ă©rrendszeri betegsĂ©gek mortalitási rátája. A jövĹ‘ben egyre több
olyan betegre számĂthatunk, akiket mind a kĂ©t betegsĂ©gtĂpus Ă©rint. Tekintettel arra, hogy mindkĂ©t betegsĂ©g kialakulása
multifaktoriális okokra vezethető vissza, számos megegyező molekuláris kialakulási útvonal, patomechanikus ténye-
ző, illetve etiológiai faktor játszik szerepet a kórképek előfordulásában. A daganatos betegségek direkt úton, illetve a
radio és/vagy kemoterápián keresztül indirekt úton is rendelkeznek ateroszklerózis és artériás megbetegedést okozó
hatásokkal. Összefoglaló cikkünkben a daganatos megbetegedések ateroszklerotikus és artériás elváltozásokkal való
összefüggését mutatjuk be. | The 21st century can be defined as an anthropogenic age, in which, in addition to the rapid economic growth by the
industrial revolution, many environmental and health damages were also created, including the increased incidence of
serious chronic diseases. Nowadays atherosclerotical, arterial and oncological diseases are one of the biggest public
health challenges all over the world with high mortality rate. Survival rates of cancers are improving thanks to increa-
singly effective treatment options. There are currently approximately 12 million cancer survivors in Europe. Cardiovas-
cular diseases are the leading cause of death globally, taking an estimated 17.9 million lives each year. In the future
patients affected by both these illnesses are become more common. Due to both diseases have multifactorial etiology
there are numerous identical molecular pathways, etiological factor and pathomechanism behind their development.
Cancerous diseases can cause atherosclerosis and arterial disease directly, or indirectly via chemo and/or radiothera-
py. Our aim is to present the correlation between cancer, atherosclerotic and arterial changes
CT or Invasive Coronary Angiography in Stable Chest Pain.
Background: In the diagnosis of obstructive coronary artery disease (CAD), computed tomography (CT) is an accurate, noninvasive alternative to invasive coronary angiography (ICA). However, the comparative effectiveness of CT and ICA in the management of CAD to reduce the frequency of major adverse cardiovascular events is uncertain.
Methods: We conducted a pragmatic, randomized trial comparing CT with ICA as initial diagnostic imaging strategies for guiding the treatment of patients with stable chest pain who had an intermediate pretest probability of obstructive CAD and were referred for ICA at one of 26 European centers. The primary outcome was major adverse cardiovascular events (cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke) over 3.5 years. Key secondary outcomes were procedure-related complications and angina pectoris.
Results: Among 3561 patients (56.2% of whom were women), follow-up was complete for 3523 (98.9%). Major adverse cardiovascular events occurred in 38 of 1808 patients (2.1%) in the CT group and in 52 of 1753 (3.0%) in the ICA group (hazard ratio, 0.70; 95% confidence interval [CI], 0.46 to 1.07; P = 0.10). Major procedure-related complications occurred in 9 patients (0.5%) in the CT group and in 33 (1.9%) in the ICA group (hazard ratio, 0.26; 95% CI, 0.13 to 0.55). Angina during the final 4 weeks of follow-up was reported in 8.8% of the patients in the CT group and in 7.5% of those in the ICA group (odds ratio, 1.17; 95% CI, 0.92 to 1.48).
Conclusions: Among patients referred for ICA because of stable chest pain and intermediate pretest probability of CAD, the risk of major adverse cardiovascular events was similar in the CT group and the ICA group. The frequency of major procedure-related complications was lower with an initial CT strategy. (Funded by the European Union Seventh Framework Program and others; DISCHARGE ClinicalTrials.gov number, NCT02400229.)