42 research outputs found
Overview of LHCb electronics installation aspects
The infrastructure for the electronics, such as cabling, mains power distribution, low and high voltage power supplies, detector safety system, grounding and its installation in the LHCb experimental cavern is presented. In addition, racks, cable ducts installation and optical fiber link tests are described
The VocADom Project: Speech Interaction for Well-being and Reliance Improvement
International audienceThe additional fee must be paid to ACM. This text field is large enough to hold the appropriate release statement assuming it is single spaced. Every submission will be assigned their own unique DOI string to be included here. Abstract The VocADom project aims to provide audio-based interaction technology that lets the users have full control over their home environment and at eases the social inclusion of the elderly and frail population. This paper presents an overview of the project focusing on multimodal corpus acquisition and labelling and on investigated techniques for speech enhancement and understanding
The c.429_452 duplication of the ARX gene: a unique developmental-model of limb kinetic apraxia:
BACKGROUND: The c.429_452dup24 of the ARX gene is a rare genetic anomaly, leading to X-Linked Intellectual Disability without brain malformation. While in certain cases c.429_452dup24 has been associated with specific clinical patterns such as Partington syndrome, the consequence of this mutation has been also often classified as "non-specific Intellectual Disability". The present work aims at a more precise description of the clinical features linked to the c.429_452dup24 mutation. METHODS: We clinically reviewed all affected patients identified in France over a five-year period, i.e. 27 patients from 12 different families. Detailed cognitive, behavioural, and motor evaluation, as well as standardized videotaped assessments of oro-lingual and gestural praxis, were performed. In a sub-group of 13 ARX patients, kinematic and MRI studies were further accomplished to better characterize the motor impairment prevalent in the ARX patients group. To ensure that data were specific to the ARX gene mutation and did not result from low-cognitive functioning per se, a group of 27 age- and IQ-matched Down syndrome patients served as control. RESULTS: Neuropsychological and motor assessment indicated that the c.429_452dup24 mutation constitutes a recognizable clinical syndrome: ARX patients exhibiting Intellectual Disability, without primary motor impairment, but with a very specific upper limb distal motor apraxia associated with a pathognomonic hand-grip. Patients affected with the so-called Partington syndrome, which involves major hand dystonia and orolingual apraxia, exhibit the most severe symptoms of the disorder. The particular "reach and grip" impairment which was observed in all ARX patients, but not in Down syndrome patients, was further characterized by the kinematic data: (i) loss of preference for the index finger when gripping an object, (ii) major impairment of fourth finger deftness, and (iii) a lack of pronation movements. This lack of distal movement coordination exhibited by ARX patients is associated with the loss of independent digital dexterity and is similar to the distortion of individual finger movements and posture observed in Limb Kinetic Apraxia. CONCLUSION: These findings suggest that the ARX c.429_452dup24 mutation may be a developmental model for Limb Kinetic Apraxia
Les Traitements non médicamenteux de la maladie d'alzheimer (évaluation de deux thérapies dans le cadre de l'étude ETNA 3)
NICE-BU MĂ©decine Odontologie (060882102) / SudocSudocFranceF
Renouveler les pratiques de mise en débat des pratiques numériques de travail. La méthodologie de l’Éducation Populaire à l’écoute des tensions
International audienc
Renouveler les pratiques de mise en débat des pratiques numériques de travail. La méthodologie de l’Éducation Populaire à l’écoute des tensions
International audienc
Enjeux et impacts de la connexion au travail ; régulations individuelles et collective
International audienc
Quels espaces d’échanges dans l’entreprise ? Un exemple de théâtre-forum pour les problèmes d’hyper-connexion.
International audienc