The electromagnetic dipole operator effect on B -> Xs gamma at O(alpha_s^2)

The flavor-changing electromagnetic dipole operator O_7 gives the dominant contribution to the B -> Xs gamma decay rate. We calculate two-loop QCD corrections to its matrix element together with the corresponding bremsstrahlung contributions. The optical theorem is applied, and the relevant imaginary parts of three-loop diagrams are computed following the lines of our recent t -> Xb W calculation. The complete result allows us to test the validity of the naive non-abelianization (NNA) approximation that has been previously applied to estimate the NNLO QCD correction to Gamma(B -> Xs gamma)/Gamma(B -> Xu e nu). When both decay widths are normalized to m^5_{b,R} in the same renormalization scheme R, the calculated O(alpha_s^2) correction is sizeable (~ 6%), and the NNA estimate is about 1/3 too large. On the other hand, when the ratio of the decay widths is written as S*(m_b(m_b)/m_{b,pole})^2, the calculated O(alpha_s^2) correction to S is at the level of 1% for both the complete and the NNA results.Comment: Corrected pi^2 terms in the description of intermediate steps in Section II. Final results unchange

Discovery of extended radio emission in the young cluster Wd1

We present 10 micron, ISO-SWS and Australia Telescope Compact Array observations of the region in the cluster Wd1 in Ara centred on the B[e] star Ara C. An ISO-SWS spectrum reveals emission from highly ionised species in the vicinity of the star, suggesting a secondary source of excitation in the region. We find strong radio emission at both 3.5cm and 6.3cm, with a total spatial extent of over 20 arcsec. The emission is found to be concentrated in two discrete structures, separated by 14''. The westerly source is resolved, with a spectral index indicative of thermal emission. The easterly source is clearly extended and nonthermal (synchrotron) in nature. Positionally, the B[e] star is found to coincide with the more compact radio source, while the southerly lobe of the extended source is coincident with Ara A, an M2 I star. Observation of the region at 10micron reveals strong emission with an almost identical spatial distribution to the radio emission. Ara C is found to have an extreme radio luminosity in comparison to prior radio observations of hot stars such as O and B supergiants and Wolf-Rayet stars, given the estimated distance to the cluster. An origin in a detatched shell of material around the central star is therefore suggested; however given the spatial extent of the emission, such a shell must be relatively young (10^3 yrs). The extended non thermal emission associated with the M star Ara A is unexpected; to the best of our knowledge this is a unique phenomenon. SAX (2-10keV) observations show no evidence of X-ray emission, which might be expected if a compact companion were present.Comment: 5 pages including encapsulated figures, figure 3 separate. Accepted for MNRAS pink page

Early warning signals for predicting cryptomarket vendor success using dark net forum networks

In this work we focus on identifying key players in dark net cryptomarkets. Law enforcement aims to disrupt criminal activity conducted through these markets by targeting key players vital to the market's existence and success. We particularly focus on detecting successful vendors responsible for the majority of illegal trade. Our methodology aims to uncover whether the task of key player identification should center around plainly measuring user and forum activity, or that it requires leveraging specific patterns of user communication. We focus on a large-scale dataset from the Evolution cryptomarket, which we model as an evolving communication network. While user and forum activity measures are useful for identifying the most successful vendors, we find that betweenness centrality additionally identifies those with lesser activity. But more importantly, analyzing the forum data over time, we find evidence that attaining a high betweenness score comes before vendor success. This suggests that the proposed network-driven approach of modelling user communication might prove useful as an early warning signal for key player identification

Possible overlapping time frames of acquisition and consolidation phases in object memory processes: a pharmacological approach

In previous studies, we have shown that acetylcholinesterase inhibitors and phosphodiesterase inhibitors (PDE-Is) are able to improve object memory by enhancing acquisition processes. On the other hand, only PDE-Is improve consolidation processes. Here we show that the cholinesterase inhibitor donepezil also improves memory performance when administered within 2 min after the acquisition trial. Likewise, both PDE5-I and PDE4-I reversed the scopolamine deficit model when administered within 2 min after the learning trial. PDE5-I was effective up to 45 min after the acquisition trial and PDE4-I was effective when administered between 3 and 5.5 h after the acquisition trial. Taken together, our study suggests that acetylcholine, cGMP, and cAMP are all involved in acquisition processes and that cGMP and cAMP are also involved in early and late consolidation processes, respectively. Most important, these pharmacological studies suggest that acquisition processes continue for some time after the learning trial where they share a short common time frame with early consolidation processes. Additional brain concentration measurements of the drugs suggest that these acquisition processes can continue up to 4–6 min after learning

HIF-1 alpha-independent hypoxia-induced rapid PTK6 stabilization is associated with increased motility and invasion

© 2014 Landes Bioscience. PTK6/Brk is a non-receptor tyrosine kinase overexpressed in cancer. Here we demonstrate that cytosolic PTK6 is rapidly and robustly induced in response to hypoxic conditions in a HIF-1-independent manner. Furthermore, a proportion of hypoxic PTK6 subsequently re-localized to the cell membrane. We observed that the rapid stabilization of PTK6 is associated with a decrease in PTK6 ubiquitylation and we have identified c-Cbl as a putative PTK6 E3 ligase in normoxia. The consequences of hypoxia-induced PTK6 stabilization and subcellular re-localization to the plasma membrane include increased cell motility and invasion, suggesting PTK6 targeting as a therapeutic approach to reduce hypoxia-regulated metastatic potential. This could have particular significance for breast cancer patients with triple negative disease

Pion pole contribution to hadronic light-by-light scattering and muon anomalous magnetic moment

We derive an analytic result for the pion pole contribution to the light-by-light scattering correction to the anomalous magnetic moment of the muon, $a_\mu = (g_\mu-2)/2$. Using the vector meson dominance model (VMD) for the pion transition form factor, we obtain $a_\mu^{{\rm LBL},\pi^0} = +56 \times 10^{-11}$.Comment: 4 pages, revte

Hadronic Light-by-Light Contribution to Muon g-2 in Chiral Perturbation Theory

We compute the hadronic light-by-light scattering contributions to the muon anomalous magnetic moment, \amulbl, in chiral perturbation theory that are enhanced by large logarithms and a factor of $N_C$. They depend on a low-energy constant entering pseudoscalar meson decay into a charged lepton pair. The uncertainty introduced by this constant is $\pm 60\times 10^{-11}$, which is comparable in magnitude to the present uncertainty entering the leading-order vacuum polarization contributions to the anomalous moment. It may be reduced to some extent through an improved measurement of the $\pi^0\to e^+ e^-$ branching ratio. However, the dependence of \amulbl on non-logarithmically enhanced effects cannot be constrained except through the measurement of the anomalous moment itself. The extraction of information on new physics would require a future experimental value for the anomalous moment differing significantly from the 2001 result reported by the E821 collaboration.Comment: 7 pages, 2 figure