Additional file 6: Figure S6. of The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical

Showing association between age of onset and onset of symptoms within RA patients of the Leiden EAC. (a) Results of logistic regression analyses of age at RA onset in relation to the onset of symptoms. OR of 1.01 indicates that per 1-year increase in the age of onset, the odds of having (sub)acute onset increase 1%. This reflects 12% (1.0110) per 10-year increase in age of onset and 25% (1.0120) per 20-year increase in age of onset. (b) Proportion of RA patients with (sub)acute onset of symptoms in three age groups (p = 0.003). Number of patients per age group: <40, n = 181; 40–60, n = 466; >60, n = 537. (TIF 2476 kb