Klinische und rechtliche Aspekte einer Abstinenzkontrolle unter besonderer Berücksichtigung kontinuierlicher transdermaler Alkoholmessung

Gerichte können einem Täter, der wegen Straftaten verurteilt wurde, die auf seinen Suchtmittelkonsum zurückgehen, die Weisung erteilen, jeglichen Alkoholkonsum zu unterlassen und sich entsprechenden Kontrollen zu unterziehen. Die Kontrolle der Weisungen stößt jedoch bislang an enge Grenzen. Bisher kann deren Einhaltung nur stichprobenartig überprüft werden. Einen neuen Ansatz bietet eine kontinuierliche (transdermale) Alkoholüberwachung mittels eines am Fußgelenk getragenen Messgerätes. Ein Blick in die USA zeigt, dass die elektronische Überwachung des Alkoholkonsums erprobt wurde und sich durchgesetzt hat. Der Beitrag untersucht die Bedeutung einer kontinuierlichen transdermalen Alkoholüberwachung für die Abstinenzkontrolle und inwieweit diese Methode im deutschen System verankert werden kann

Innovation and Foreign Investment Behavior of the U.S. Pharmaceutical Industry

This paper deals with the links between the development of new drugs, and particularly of innovative new drugs, and the international activities of U.S. drug companies. While U.S. drug companies have developed new production processes - the most notable being the fermentation process for making penicillin - we concentrate in this paper on new products. Since production costs comprise less than 40 percent of the selling price of drugs and since the person choosing the drug rarely pays for it, growth in company sales and profits comes more from introducing new products than from cutting costs and prices of old products. The main novelty of our study is our examination of "innovative" as contrasted with "imitative" new drugs. Previous studies have generally focused on the total number of new drugs produced each year, but since our interest is in the causes and consequences of innovation, we have concentrated on the products we have rated as innovative. Section I explains our criteria for this distinction and presents our enumeration of the innovative new drugs for each of the 22 companies in our sample. In Section II we discuss trends in the rate of drug innovation and the factors influencing those trends. Section III describes our sample of drug companies and characterizes them with respect to their size, research investment, and innovativeness. Section IV examines the relation of innovativeness to the foreign activities of individual firms. In Section V we analyze, for a sample of 7 new drugs introduced by two companies, the rate at which use of the drugs was diffused among various countries arid the impact of the presence of manufacturing plants on the rate of diffusion.