High rate dose brachytherapy - HDR experience for localized and locally advanced prostate cancer in Sverdlovsk Regional Oncology Dispensary

Currently, the rate of morbidity and mortality from prostate cancer has been increasing. HDR brachytherapy (HDR-ВТ) is considered to be one of the modern methods in the treatment of prostate cancer. In Sverdlovsk Regional Oncology Centre (SROC) this method has been being applied since 2009. In our work we analyzed treatment outcomes in 204 patients with localized and locally advanced prostate cancer after HDR as a single method as well as a part of combined and complex treatment. Our results evidenced of HDR brachytherapy as an effective and safe method of treatment, which improves hospitalization.В настоящее время в России отмечается рост заболеваемости и смертности от рака предстательной железы. Одним из современных методов лечения данной патологии является внутритканевая высокодозная брахитерапия - HDR (High dose rate). В Свердловском областном онкологическом диспансере (СООД) этот метод лечения применяется с 2009 г. В данной работе приводится анализ результатов лечения 204 больных локальным и местно-распространенным раком простаты с применением HDR как в самостоятельном плане, так и в составе комбинированного и/или комплексного лечения. Полученные нами результаты свидетельствуют о том, что высокодозная брахитерапия - HDR является эффективным и безопасным методом лечения, не требующим длительных сроков госпитализации больных

Stereotactic body radiation therapy (SBRT) in the treatment of spine metastases at the linear accelerator in Sverdlovsk Regional Oncology Center

Modern technology of radiation therapy (IMRT, SBRT, etc) are used for patients receiving radical treatment program with an expected high oncological result. However, for patients with single metastases to the spine can be applied the strategy of conditionally radical treatment, including the achievement of full local control of metastatic lesion followed adequately chosen a specific treatment. In the last case, the survival rate can reach several years. In S00D we use the technique of stereotactic body radiotherapy with 2012 for patients with metastases in the vertebrae. Currently treated 32 people, the effectiveness of treatment was 90,6% in terms of relief of pain. The method is effective and relatively safe method of treatment allows to reduce treatment time.Современные технологии лучевой терапии (IMRT, SBRT и др) используются для пациентов, получающих радикальную программу лечения с ожидаемым высоким онкологическим результатом. Однако для пациентов с одиночными метастазами в позвоночник может быть применена стратегия условно-радикального лечения, включающая в себя достижение полного локального контроля метастатического очага с последующим адекватно подобранным специфическим лечением. В последнем случае выживаемость пациентов может достигать нескольких лет. В СООД мы используем методику стереотаксической лучевой терапии с 2012 года для пациентов метастазами в позвонки. В настоящее время пролечено 32 человека, эффективность лечения составила 90,6% в плане купирования болевого синдрома. Методика является эффективным и достаточно безопасным методом лечения, позволяет сократить сроки лечения

Segregation effects in surface layers of titanium-based amorphous alloys in deformation

Translated from Russian (Fiz. Khim. Obrab. Mater. 1995 (6) p. 97-101)Available from British Library Document Supply Centre-DSC:9023.170(VR-Trans--9209)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Temperature dependence of segregation of metalloids in Fe-S-P-C amorphous alloys

Translated from Russian (Fiz. Khim. Obrab. Mater. 1996 (2) p. 110-116)SIGLEAvailable from British Library Document Supply Centre-DSC:9023.190(VR-Trans--9020)T / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Changes of the composition of the surface and structural transformations in the process of corrosion of Fe-Cr-P-C amorphous alloys

Translated from Russian (Fiz. Khim. Obrab. Mater. 1996 (5) p. 135-141)Available from British Library Document Supply Centre-DSC:9023.190(9784)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Change of the composition of surface layers of Fe-Mo-P-C amorphous alloy under creep conditions

Translated from Russian (Fiz. Khim. Obrab. Mater. 1996 (1) p. 127-131)Available from British Library Document Supply Centre-DSC:9023.190(VR-Trans--9088)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Model of the formation of ion-implanted layers of the metal-metalloid system

Translated from Russian (Fiz. Khim. Obrab. Mater. 1998 (5) p. 16-18)Available from British Library Document Supply Centre-DSC:9023.190(10204)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Dose changes of the surface layers of steel in implantation of argon ions

In ion implantation, especially at high doses, interesting processes includes the condensation and implantation into the surface layers of the matrix of C in the gaseous state in the form of C-O and C-H in the vacuum chamber of ion-beam equipment and, in particular, in oil pumping. The implanted C influences the formation of the ion-implanted layer as a result of its high service of chemical activity. However, in addition to the C compounds, the chamber of the equipment for residual gas also contains oxygen, taking into account the fact that ion implantation is carried out using mean vacuum of the level of approximately 10"-"4 Pa. In implantation of the ions of active elements (phosphorus or boron) into 20Kh13 steel there was no significant effect of oxygen of the chemical composition of the surface less of the target at all examined doses. At the initial doses of 1x10"1"7 ion/cm"2, in implantation of the ions of active elements the surface layers are amorphised, and with increase of the implantation dose of the P"+ ions the structure undergoes recrystallisation, and at a dose of 5x10"1"7 ion/cm"2 the surface layers contained a texturised polycrystal; in the case of implantation of the B"+ ions, recrystallisation does not take place. In this case, in the implantation of the ions of chemical active elements the initial stages characterised by the formation of groups (complexes) of the atoms of the metal-metalloid with the covalent type of chemical bonding with further formation of precipitates with the structure of texturised polycrystals identical with the texturisation of thin films of the substrate. The different situation is observed in implantation of the ions of the inert gas -argonTranslated from Russian (Fiz. Khim. Obrab. Mater. 1996 (5) p. 158-162)TAvailable from British Library Document Supply Centre-DSC:9023.190(VR-Trans--9024)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Oxidation of coatings based on titanium nitride in air at moderate temperatures

20.00; Translated from Russian (Fiz. Khim. Obrab. Mater. 1989 v. 23(5) p. 118-121)Available from British Library Document Supply Centre- DSC:9023.19(VR-Trans--4714)T / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Otoliths as object of EPR dosimetric research

Otoliths are the organs which fish use for hearing and keeping balance. Otoliths are the most calcified tissues in the fish body. In contrast to bones, otoliths are not affected by remodeling and, therefore, they are expected to accumulate any dose from ionizing radiation during lifetime. Therefore, EPR dosimetry with fish otoliths could be an important tool for dose reconstruction in radiobiology and radioecology. It could also provide useful information remediation actions to de-contaminate waterbodies. Consequently, in the present study, otoliths of three contaminated fish species (roach (Rutilus rutilus), pike (Esox lucius) and perch (Perca Fluviatilis)) were examined with Electron Paramagnetic Resonance (EPR) spectroscopy. The fish were caught at storage reservoirs of liquid radioactive waste from Mayak PA and from the upper reach of the Techa River, which have been contaminated with different levels of radionuclide activity concentrations. It is shown that the radiationinduced EPR signal of otolith is stable and characterized by a linear dose response. However, the slope of the calibration curve (corresponding to the radiation sensitivity of the material) is not the same for different species; this may be caused by differences in mineralization. The reconstructed doses were found to be in the range from undetectable (in fish from the upper stream of the Techa River) up to 265 Gy (in roach from the most contaminated waterbody). In parallel, otoliths were measured with beta-counter to detect Sr-90/Y-90. Samples were also tested on the presence of alpha-emitters, but no alpha activity above background could be detected. However, a significant activity concentration of Sr-90 was detected (from 1 x 10(1) to 2 x 10(4) Bq/g). The EPR doses measured correlated with the Sr-90 activity concentration measured in the otolith samples