75 research outputs found
Continuous selections of multivalued mappings
This survey covers in our opinion the most important results in the theory of
continuous selections of multivalued mappings (approximately) from 2002 through
2012. It extends and continues our previous such survey which appeared in
Recent Progress in General Topology, II, which was published in 2002. In
comparison, our present survey considers more restricted and specific areas of
mathematics. Note that we do not consider the theory of selectors (i.e.
continuous choices of elements from subsets of topological spaces) since this
topics is covered by another survey in this volume
Consonance and Cantor set-selectors
It is shown that every metrizable consonant space is a Cantor set-selector. Some applications are derived from this fact, also the relationship is discussed in the framework of hyperspaces and Prohorov spaces.peer-reviewe
Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study
Purpose: The DIANA study aimed to evaluate how often antimicrobial de-escalation (ADE) of empirical treatment is performed in the intensive care unit (ICU) and to estimate the effect of ADE on clinical cure on day 7 following treatment initiation. Methods: Adult ICU patients receiving empirical antimicrobial therapy for bacterial infection were studied in a prospective observational study from October 2016 until May 2018. ADE was defined as (1) discontinuation of an antimicrobial in case of empirical combination therapy or (2) replacement of an antimicrobial with the intention to narrow the antimicrobial spectrum, within the first 3 days of therapy. Inverse probability (IP) weighting was used to account for time-varying confounding when estimating the effect of ADE on clinical cure. Results: Overall, 1495 patients from 152 ICUs in 28 countries were studied. Combination therapy was prescribed in 50%, and carbapenems were prescribed in 26% of patients. Empirical therapy underwent ADE, no change and change other than ADE within the first 3 days in 16%, 63% and 22%, respectively. Unadjusted mortality at day 28 was 15.8% in the ADE cohort and 19.4% in patients with no change [p = 0.27; RR 0.83 (95% CI 0.60\u20131.14)]. The IP-weighted relative risk estimate for clinical cure comparing ADE with no-ADE patients (no change or change other than ADE) was 1.37 (95% CI 1.14\u20131.64). Conclusion: ADE was infrequently applied in critically ill-infected patients. The observational effect estimate on clinical cure suggested no deleterious impact of ADE compared to no-ADE. However, residual confounding is likely
Науково-практичний коментар Закону України «Про запобігання корупції» [станом на 1 лип. 2018 р.]
Науково-практичний коментар Закону України «Про запобігання корупції»: станом на 1 лип. 2018 р. / [А. В. Андрєєв, І. Л. Антипова, С. В. Банах та ін.], за заг. ред. Журавльова Д. В. – Київ: Видав. дім «Професіонал», 2018. – 512 с.Коментар розрахований на осіб, уповноважених на виконання функцій
держави або місцевого самоврядування та прирівняних до них осіб, які є
суб’єктами, на яких поширюється дія Закону України «Про запобігання корупції», на уповноважених осіб, відповідальних за реалізацію антикорупційних
програм, суддів, прокурорів, слідчих, детективів, адвокатів, а також на студентів вищих учбових закладів, які готують фахівців в галузі права
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