Simplified modelling of chiral lattice materials with local resonators

A simplified model of periodic chiral beam-lattices containing local resonators has been formulated to obtain a better understanding of the influence of the chirality and of the dynamic characteristics of the local resonators on the acoustic behavior. The simplified beam-lattices is made up of a periodic array of rigid heavy rings, each one connected to the others through elastic slender massless ligaments and containing an internal resonator made of a rigid disk in a soft elastic annulus. The band structure and the occurrence of low frequency band-gaps are analysed through a discrete Lagrangian model. For both the hexa- and the tetrachiral lattice, two acoustic modes and four optical modes are identified and the influence of the dynamic characteristics of the resonator on those branches is analyzed together with some properties of the band structure. By approximating the generalized displacements of the rings of the discrete Lagrangian model as a continuum field and through an application of the generalized macro-homogeneity condition, a generalized micropolar equivalent continuum has been derived, together with the overall equation of motion and the constitutive equation given in closed form. The validity limits of the micropolar model with respect to the dispersion functions are assessed by comparing the dispersion curves of this model in the irreducible Brillouin domain with those obtained by the discrete model, which are exact within the assumptions of the proposed simplified model

Second-order homogenization of periodic materials based on asymptotic approximation of the strain energy: formulation and validity limits

In this paper a second-order homogenization approach for periodic material is derived from an appropriate representation of the down-scaling that correlates the microdisplacement field to the macro-displacement field and the macro-strain tensors involving unknown perturbation functions. These functions take into account of the effects of the heterogeneities and are obtained by the solution of properly defined recursive cell problems. Moreover, the perturbation functions and therefore the micro-displacement fields result to be sufficiently regular to guarantee the anti-periodicity of the traction on the periodic unit cell. A generalization of the macro-homogeneity condition is obtained through an asymptotic expansion of the mean strain energy at the micro-scale in terms of the microstructural characteristic size e; the obtained overall elastic moduli result to be not affected by the choice of periodic cell. The coupling between the macro- and microstress tensor in the periodic cell is deduced from an application of the generalised macrohomogeneity condition applied to a representative portion of the heterogeneous material (cluster of periodic cell). The correlation between the proposed asymptotic homogenization approach and the computational second-order homogenization methods is obtained through an approximation of the macrodisplacement field based on a second-order Taylor expansion. The form of the overall elastic moduli obtained through the two homogenization approaches, here proposed, is analyzed and the differences are highlighted

Aplastic Anemia: Pathogenesis and Treatment

Abstract This review highlights some of the contributions that have appeared in the literature in the past decade on the pathogenesis and treatment of aplastic anemia (AA). This summary is brief because the field is vast, spaning from stem cell biology to stem cell disorders, from autoimmunity to transplantation, from graft-versus-host disease to late effects. The immune pathogenesis of AA is now based on several lines of evidence and will be discussed. Immunosuppressive therapy (IST) remains an important option for AA patients who are not candidates for transplantation. Favorable prognostic indicators for IST are young age and a short interval from diagnosis; the neutrophil count seems to have lost its predictive value with current antithymocyte globulin–cyclsoporin combination therapy. The outcome of allogeneic bone marrow transplantations has significantly improved in the past decade, particularly in the unrelated donor setting, to such an extent that treatment strategies may be affected. A short interval between diagnosis and treatment will also improve results for bone marrow transplantation; these rare patients should be referred to an experienced center immediately

Back to the OR?

n/

Wave propagation in non-centrosymmetric beam-lattices with lumped masses: discrete and micropolar modelling

The in-plane acoustic behavior of non-centrosymmetric lattices having nodes endowed with mass and rotational inertia and connected by massless ligaments with asymmetric elastic properties has been analyzed through a discrete model and a continuum micropolar model. In the first case the propagation of harmonic waves and the dispersion functions have been obtained by the discrete Floquet–Bloch approach. It is shown that the optical branch departs from a critical point with vanishing group velocity and is decreasing for increasing the norm of the wave vector. A micropolar continuum model has been derived through a continualization method based on a down-scaling law from a second-order Taylor expansion of the generalized macro-displacement field. It is worth noting that the second order elasticity tensor coupling curvatures and micro-couples turns out to be negative-definite also in the general case of non-centrosymmetric lattice. The eigenvalue problem governing the harmonic propagation in the micropolar non-centrosymmetric continuum results in general characterized by a hermitian full matrix that is exact up to the second order in the wave vector. Examples concerning square and equilateral triangular lattices have been analyzed and their acoustic properties have been derived with the discrete and continuum models. The dependence of the Floquet–Bloch spectra on the lattice non-centrosymmetry is shown together with validity limits of the micropolar model. Finally, in consideration of the negative definiteness of the second order elastic tensor of the micropolar model, the loss of strong hyperbolicity of the equation of motion has been investigated

A micropolar model for the analysis of dispersive waves in chiral mass-in-mass lattices

The possibility of obtaining band gap structures in chiral auxetic lattices is here considered and applied to the case of inertial locally resonant structures. These periodic materials are modelled as beam-lattices made up of a periodic array of rigid rings, each one connected to the others through elastic slender ligaments. To obtain low-frequency stop bands, elastic circular resonating inclusions made up of masses located inside the rings and connected to them through an elastic surrounding interface are considered and modeled. The equations of motion are obtained for an equivalent homogenized micropolar continuum and the overall elastic moduli and the inertia terms are given for both the hexachiral and the tetrachiral lattice. The constitutive equation of the beam lattice given by the Authors [15] are then applied and a system of six equations of motion is obtained. The propagation of plane waves travelling along the direction of the lines connecting the ring centres of the lattice is analysed and the secular equation is derived, from which the dispersive functions may be obtained

Multi-parametric sensitivity analysis of the band structure for tetrachiral inertial metamaterials

Tetrachiral materials are characterized by a cellular microstructure made by a periodic pattern of stiff rings and flexible ligaments. Their mechanical behaviour can be described by a planar lattice of rigid massive bodies and elastic massless beams. The periodic cell dynamics is governed by a monoatomic structural model, conveniently reduced to the only active degrees-of-freedom. The paper presents an explicit parametric description of the band structure governing the free propagation of elastic waves. By virtue of multiparametric perturbation techniques, sensitivity analyses are performed to achieve analytical asymptotic approximation of the dispersion functions. The parametric conditions for the existence of full band gaps in the low-frequency range are established. Furthermore, the band gap amplitude is analytically assessed in the admissible parameter range. In inertial tetrachiral metamaterials, stop bands can be opened by the introduction of intra-ring resonators. Perturbation methods can efficiently deal with the consequent enlargement of the mechanical parameter space. Indeed high-accuracy parametric approximations are achieved for the band structure, enriched by the new optical branches related to the resonator frequencies. In particular, target stop bands in the metamaterial spectrum are analytically designed through the asymptotic solution of inverse spectral problems. Subjects: Materials Science (cond-mat.mtrl-sci) Cite as: arXiv:1706.08754 [cond-mat.mtrl-sci] (or arXiv:1706.08754v1 [cond-mat.mtrl-sci] for this version

Damped Bloch Waves in Lattices Metamaterials with Inertial Resonators

The present paper is focused on the acoustic behaviour of periodic beam-lattices metamaterials containing inertial viscoelastic resonators connected with elastic slender ligaments. A simplified model is considered where the ligaments are considered as massless and the viscoelastic resonators are contained inside rigid rings located at the lattice nodes. Firstly, a Lagrangian model is formulated in order to assess the influence of the dynamic and viscoelastic properties of the resonators on the acoustic behaviour. An equivalent generalized micropolar model is obtained through a continualization of the discrete model and the constitutive tensors and the equation of motion are formulated. The propagation of harmonic waves is assumed and the Christoffel equation for both the discrete and the continuum model are obtained. It is shown that the hermitian matrix governing the Christoffel equation of the Lagrangian model is approximated by the corresponding one from the micropolar model with an error O (|k|3

Identifying the Best Haploidentical Donor: Are We There?

n/

Overall thermomechanical properties of layered materials for energy devices applications

This paper is concerned with the analysis of effective thermomechanical properties of multi- layered materials of interest for solid oxide fuel cells (SOFC) and lithium ions batteries fabrication. The recently developed asymptotic homogenization procedure is applied in order to express the overall thermoelastic constants of the first order equivalent continuum in terms of microfluctuations functions, and these functions are obtained by the solution of the corresponding recursive cell problems. The effects of thermal stresses on periodic multi-layered thermoelastic composite reproducing the characteristics of solid oxide fuel cells (SOFC-like) are studied assuming periodic body forces and heat sources, and the solution derived by means of the asymptotic homogenization approach is compared with the results obtained by finite elements analysis of the associate heterogeneous material