222 research outputs found
Assessing competency for concealed-weapons permits - The physician's role
Shortly after the shootings in Newtown, Connecticut, two of us received letters from our county sheriff in North Carolina asking whether one of our patients had medical or physical conditions that would preclude issuance of a permit to carry a concealed weapon. Uncomfortable with our limited knowledge about such permits and our expected role, and fearing that our participation could affect our relationships with patients, we began exploring the ethical, legal, and policy considerations regarding physician involvement in this process
A (Running) Bolt for New Reasons
We construct a four-parameter family of smooth, horizonless, stationary
solutions of ungauged five-dimensional supergravity by using the
four-dimensional Euclidean Schwarzschild metric as a base space and
"magnetizing" its bolt. We then generalize this to a five-parameter family
based upon the Euclidean Kerr-Taub-Bolt. These "running Bolt" solutions are
necessarily non-static. They also have the same charges and mass as a
non-extremal black hole with a classically-large horizon area. Moreover, in a
certain regime their mass can decrease as their charges increase. The existence
of these solutions supports the idea that the singularities of non-extremal
black holes are resolved by low-mass modes that correct the singularity of the
classical black hole solution on large (horizon-sized) scales.Comment: 25 pages, 3 figures, LaTeX; v2: minor changes, references adde
Physician attitudes and experience with permit applications for concealed weapons
To the Editor: Every U.S. state allows people to carry concealed weapons within certain limits and after varied approval processes. Although many states require physician participation to help determine competency, it is not known whether physicians are capable of assessing a patient’s competence to carry a concealed weapon
Solar Neutrino Constraints on the BBN Production of Li
Using the recent WMAP determination of the baryon-to-photon ratio, 10^{10}
\eta = 6.14 to within a few percent, big bang nucleosynthesis (BBN)
calculations can make relatively accurate predictions of the abundances of the
light element isotopes which can be tested against observational abundance
determinations. At this value of \eta, the Li7 abundance is predicted to be
significantly higher than that observed in low metallicity halo dwarf stars.
Among the possible resolutions to this discrepancy are 1) Li7 depletion in the
atmosphere of stars; 2) systematic errors originating from the choice of
stellar parameters - most notably the surface temperature; and 3) systematic
errors in the nuclear cross sections used in the nucleosynthesis calculations.
Here, we explore the last possibility, and focus on possible systematic errors
in the He3(\alpha,\gamma)Be7 reaction, which is the only important Li7
production channel in BBN. The absolute value of the cross section for this key
reaction is known relatively poorly both experimentally and theoretically. The
agreement between the standard solar model and solar neutrino data thus
provides additional constraints on variations in the cross section (S_{34}).
Using the standard solar model of Bahcall, and recent solar neutrino data, we
can exclude systematic S_{34} variations of the magnitude needed to resolve the
BBN Li7 problem at > 95% CL. Additional laboratory data on
He3(\alpha,\gamma)Be7 will sharpen our understanding of both BBN and solar
neutrinos, particularly if care is taken in determining the absolute cross
section and its uncertainties. Nevertheless, it already seems that this
``nuclear fix'' to the Li7 BBN problem is unlikely; other possible solutions
are briefly discussed.Comment: 21 pages, 3 ps figure
Instabilities in a Two-Component, Species Conserving Condensate
We consider a system of two species of bosons of equal mass, with
interactions and for bosons of the same and different
species respectively. We present a rigorous proof -- valid when the Hamiltonian
does not include a species switching term -- showing that, when
, the ground state is fully "polarized" (consists of
atoms of one kind only). In the unpolarized phase the low energy excitation
spectrum corresponds to two linearly dispersing modes that are even a nd odd
under species exchange. The polarization instability is signaled by the vani
shing of the velocity of the odd modes.Comment: To appear in Phys. Rev.
Barrier effects on the collective excitations of split Bose-Einstein condensates
We investigate the collective excitations of a single-species Bose gas at T=0
in a harmonic trap where the confinement undergoes some splitting along one
spatial direction. We mostly consider onedimensional potentials consisting of
two harmonic wells separated a distance 2 z_0, since they essentially contain
all the barrier effects that one may visualize in the 3D situation. We find,
within a hydrodynamic approximation, that regardless the dimensionality of the
system, pairs of levels in the excitation spectrum, corresponding to
neighbouring even and odd excitations, merge together as one increases the
barrier height up to the current value of the chemical potential. The
excitation spectra computed in the hydrodynamical or Thomas-Fermi limit are
compared with the results of exactly solving the time-dependent
Gross-Pitaevskii equation. We analyze as well the characteristics of the
spatial pattern of excitations of threedimensional boson systems according to
the amount of splitting of the condensate.Comment: RevTeX, 12 pages, 13 ps figure
Roles of Fast-Cyclotron and Alfven-Cyclotron Waves for the Multi-Ion Solar Wind
Using linear Vlasov theory of plasma waves and quasi-linear theory of
resonant wave-particle interaction, the dispersion relations and the
electromagnetic field fluctuations of fast and Alfven waves are studied for a
low-beta multi-ion plasma in the inner corona. Their probable roles in heating
and accelerating the solar wind via Landau and cyclotron resonances are
quantified. We assume that (1) low-frequency Alfven and fast waves have the
same spectral shape and the same amplitude of power spectral density; (2) these
waves eventually reach ion cyclotron frequencies due to a turbulence cascade;
(3) kinetic wave-particle interaction powers the solar wind. The existence of
alpha particles in a dominant proton/electron plasma can trigger linear mode
conversion between oblique fast-whistler and hybrid alpha-proton cyclotron
waves. The fast-cyclotron waves undergo both alpha and proton cyclotron
resonances. The alpha cyclotron resonance in fast-cyclotron waves is much
stronger than that in Alfven-cyclotron waves. For alpha cyclotron resonance, an
oblique fast-cyclotron wave has a larger left-handed electric field
fluctuation, a smaller wave number, a larger local wave amplitude, and a
greater energization capability than a corresponding Alfven-cyclotron wave at
the same wave propagation angle \theta, particularly at < \theta <
. When Alfven-cyclotron or fast-cyclotron waves are present, alpha
particles are the chief energy recipient. The transition of preferential
energization from alpha particles to protons may be self-modulated by
differential speed and temperature anisotropy of alpha particles via the
self-consistently evolving wave-particle interaction. Therefore, fast-cyclotron
waves as a result of linear mode coupling is a potentially important mechanism
for preferential energization of minor ions in the main acceleration region of
the solar wind.Comment: 29 pages, 10 figures, 3 tables. Accepted for publication in Solar
Physic
Spinor condensates and light scattering from Bose-Einstein condensates
These notes discuss two aspects of the physics of atomic Bose-Einstein
condensates: optical properties and spinor condensates. The first topic
includes light scattering experiments which probe the excitations of a
condensate in both the free-particle and phonon regime. At higher light
intensity, a new form of superradiance and phase-coherent matter wave
amplification were observed. We also discuss properties of spinor condensates
and describe studies of ground--state spin domain structures and dynamical
studies which revealed metastable excited states and quantum tunneling.Comment: 58 pages, 33 figures, to appear in Proceedings of Les Houches 1999
Summer School, Session LXXI
Emerging role of insulin with incretin therapies for management of type 2 diabetes
Type 2 diabetes mellitus (T2DM) is a progressive disease warranting intensification of treatment, as beta-cell function declines over time. Current treatment algorithms recommend metformin as the first-line agent, while advocating the addition of either basal-bolus or premixed insulin as the final level of intervention. Incretin therapy, including incretin mimetics or enhancers, are the latest group of drugs available for treatment of T2DM. These agents act through the incretin axis, are currently recommended as add-on agents either as second-or third-line treatment, without concurrent use of insulin. Given the novel role of incretin therapy in terms of reducing postprandial hyperglycemia, and favorable effects on weight with reduced incidence of hypoglycemia, we explore alternative options for incretin therapy in T2DM management. Furthermore, as some evidence alludes to incretins potentially increasing betacell mass and altering disease progression, we propose introducing these agents earlier in the treatment algorithm. In addition, we suggest the concurrent use of incretins with insulin, given the favorable effects especially in relation to weight gain
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