An alternative technique for investigating fluid flow around the hand during front crawl

This paper presents the novel application of a technique for measuring flow around the hand during a simulated swim stroke with a view to enable a better understanding of propulsion generation in swimming. The technique relies on the instantaneous, non-intrusive, volumetric measurement of 3D velocity fields using a commercially available optical measurement system. A hand and forearm model was towed through a water tank to replicate the pull phase with fluid flow data being captured at regular intervals in a fixed volume through which the model moved. The measurement system included a single body, three-sensor probe for capturing pairs of images which were then processed to determine particle velocities and to characterise the flow. The results were used to investigate changes in mean velocity for six experimental cases based on three different angles of attack and two towing speeds. The results showed that the V3V system could be used to capture velocity data around the hand and for a 45° increase in angle of attack, the velocity magnitude of the flow reduced by half, indicating the presence of lift forces. © 2013 The Authors

The Development of a Methodology to Determine the Relationship in Grip Size and Pressure to Racket Head Speed in a Tennis Forehand Stroke

© 2016 The Authors. Published by Elsevier Ltd. This study developed a methodology to examine the effects of grip size and grip firmness on the kinematic contribution of angular velocity (KCAV) to the generation of racket head speed during a topspin tennis forehand. The KCAV is subdivided into kinematic contribution of joint angular velocity and kinematic contribution of the body segments in the upper trunk translational and angular velocities. Two Babolat Pure Storm GT rackets, with grip sizes 2 and 4 respectively, were used with Tekscan 9811E pressure sensors applied to the handles to examine pressure distribution during the stroke. Upper body kinematic data taken from the racket arm and trunk were obtained by means of a Vicon motion capture system. One elite male tennis player was recruited. Fifty topspin forehand strokes per grip at two nominal grip pressures were performed in a laboratory environment with balls being tossed towards the player and struck on the bounce towards a target on a net in as consistent a way as practically achievable. Processing of the results showed that the firm grip condition led to a significant (p<0.001) increase in average racket head speed compared to a normal grip condition. The normal gripping condition resulted in a significant (p<0.001) increase in average racket head speed for grip size 2 compared to grip size 4. A trend in negative linear relationships was found between upper trunk and shoulder joint in KCAV across conditions. Using the smaller grip also led to a trend in negative linear relationship between shoulder joint and wrist joint in KCAV across grip conditions. Grip pressure for grip size 2 showed the same pattern across gripping conditions. From 50-75% of completion in forward swing, the pressure difference due to grip firmness decreased. This feasibility study managed to quantify the KCAV while performing a topspin forehand, with respect to changing of grip size and grip pressure in an elite male tennis player for the first time

Development of a test methodology for the assessment of human impacts in sport

The study described in this paper aims to develop a suitable method for the measurement of contact forces, pressures and velocities of simulated human-on-human impacts typical of those experienced within American Football. A thin-film pressure sensor system was chosen to enable the impacts to be quantified, however, initial testing suggested that the measured impact forces were underestimated by circa 30% with the system calibrated in the standard, static pressure manner. A two-stage, dynamic calibration was therefore developed, in which the sensors were subsequently dynamically loaded in a manner more representative of the impacts, allowing an appropriate dynamic calibration factor to be derived. To determine the typical impact force levels experienced in a shoulder-on-thigh impact event, eight subjects were required to perform three "good" tackles at two different velocities. The processed results identified a peak, transmitted force of 1.1 (0.4) and 1.7 (0.5) kN for "low" and "medium" velocities respectively, with corresponding effective areas of application of 70 (22) cm2 and 85 (25) cm2 and contact times of 0.257 (0.098) s and 0.245 (0.112) s respectively. © 2012 Published by Elsevier Ltd

CD19+CD24hiCD38hi B Cells Are Expanded in Juvenile Dermatomyositis and Exhibit a Pro-Inflammatory Phenotype After Activation Through Toll-Like Receptor 7 and Interferon-α

Juvenile dermatomyositis (JDM) is a rare form of childhood autoimmune myositis that presents with proximal muscle weakness and skin rash. B cells are strongly implicated in the pathogenesis of the disease, but the underlying mechanisms are unknown. Therefore, the main objective of our study was to investigate mechanisms driving B cell lymphocytosis and define pathological features of B cells in JDM patients. Patients were recruited through the UK JDM Cohort and Biomarker study. Peripheral blood B cell subpopulations were immunophenotyped by flow cytometry. The results identified that immature transitional B cells were significantly expanded in active JDM, actively dividing, and correlated positively with disease activity. Protein and RNAseq analysis revealed high interferon alpha (IFNa) and TLR7-pathway signatures pre-treatment. Stimulation of B cells through TLR7/8 promoted both IL-10 and IL-6 production in controls but failed to induce IL-10 in JDM patient cells. Interrogation of the CD40-CD40L pathway (known to induce B cell IL-10 and IL-6) revealed similar expression of IL-10 and IL-6 in B cells cultured with CD40L from both JDM patients and controls. In conclusion, JDM patients with active disease have a significantly expanded immature transitional B cell population which correlated with the type I IFN signature. Activation through TLR7 and IFNa may drive the expansion of immature transitional B cells in JDM and skew the cells toward a pro-inflammatory phenotype