Fouilles archéologiques de la mosquée d’Agadīr Amghār à Aḳḳa (province de Tata)

Les fouilles archéologiques de la mosquée d’Agadīr Amghār à Aḳḳa (province de Tata)5 avaient pour objectif de lever le voile sur un site énigmatique du sud-est marocain, qui a été longtemps consi­déré comme almohade, du fait des simples similitudes existant entre l’allure de son minaret et ceux des célèbres mosquées de Marrakech et Rabat. Les investigations menées sur le terrain durant deux campagnes de fouilles, ont prouvé que cet édifice religieux date de l’époque sa‘adienne au moment où la Zaouïa d’Aḳḳa jouissait d’une grande aura sous l’impulsion de son fondateur Sīdī Muḥammad ibn Mbārk, et jouait un rôle décisif dans l’incubation du mouvement politique et religieux naissant dans le Sud au début du 16e siècle. L’agglomération hérita aussi du rôle précurseur de sa voisine en déclin, la célèbre métropole commerciale et minière de Tamdūlt

Tingitana Frontier Project. Rapport préliminaire de recherche de la mission polono-marocaine dans la région de Volubilis au Maroc pendant la saison 2018

The report presents the preliminary results of the work of the Polish-Moroccan expedition in the region of the ancient city Volubilis in 2018. The research carried out in Morocco aims to answer the question of the appearance and functioning of the border defence system of the province Mauritania Tingitana. The topic is not sufficiently developed in existing publications. Field research has provided new data and interesting field observations. Recognition of the human activity from the Roman period in the region has allowed us to collect interesting ceramic material for preliminary dating of the sites

Preventive impact of traditional medicine against covid-19

Globally, SARS-Cov-2 continues to spread, causing widespread panic. Finding a cure to stop its spread has become a top priority. The use of chloroquine has been the subject of much debate in the scientific community around the world. The Scientific Committee of Morocco decided to use it to treat cases infected with covide 19. However, treatment depends on the health of each patient’s immune system. It is necessary to strengthen the immune system to protect itself or prevent possible infections, such as colds, fever, pain, shortness of breath and sore throat, symptoms similar to those of SARS-Cov-2 virus. An infusion, prepared in a traditional way from certain plants such as thyme, lemon, ginger, with a supplement of honey, is used by the Moroccan population to strengthen the immune system during the winter period to fight against colds, fever, pain, shortness of breath and sore throat symptoms similar to those of SARS-Cov-2. Thus, this infusion can be used to naturally strengthen the body’s immunity because it contains a significant amount of vitamin C, zinc, quercetin, bioactive substances called essential for the proper functioning of cellular metabolism against pathogens and possibly the famous SARS-Cov-2

Phytochemical, Antioxidant Activity, and Toxicity of Wild Medicinal Plant of Melitotus albus Extracts, <i>In Vitro</i> and <i>In Silico</i> Approaches

Morocco is known for its high plant biodiversity, but many plants are poorly valorized. For this reason, this study aims to valorize the methanolic and aqueous extracts of Melitotus albus leaves by studying their antioxidant activity and toxicity. The extracts’ antioxidant activity is assessed using the FRAP, DPPH, CAT, and ABTS methods. The chemical composition was determined using LC–MS analysis and evaluated using in silico studies. The results revealed that the total polyphenol content of the aqueous extract, 259.26 ± 7.79 (mg GAE/g), is higher than that of the methanolic extract, 131.41 ± 12.64 (mg GAE/g). The antioxidant activity by the methods of DPPH, ABTS, and phosphor molybdenum of aqueous extracts (0.087 ± 0.015, 0.014 ± 0.001 and 6.157 ± 1.050 mg eq vit C/g, respectively) is greater than that of methanolic extracts (0.107 ± 0.02, 0.167 ± 0.03, and 0.453 ± 0.014 mg eq vit C/g, respectively). The reducing power of iron (FRAP) shows that the methanolic extract has a greater reducing power than that of the aqueous extract with a low IC50 (0.011 ± 0.003 and 0.199 ± 0.016 mg/mL, respectively). The study of acute and subacute toxicity shows that the administration of the aqueous extract of M. albus at different doses increases the body weight of rats without modifying their general behavior. The M. albus extract had a 99.99% total phenolic content, as determined by LC–MS, consisting of 12 different components. The primary constituents of the extract are chlorogenic acid (43.68%), catechin/epicatechin (24.82%), quercetin-3-O-glucuronic acid (9.91%), naringin (7.64%), and p-hydroxybenzoic/salicylic acid (2.95%). The in-silico study showed that these compounds can passively permeate through the blood and have a beneficial effect on various organs of the body. Based on these results, M. albus can be used as a medicinal plant in phytotherapy, cosmetics, or as a dietary supplement. The bioactive compounds of these plants will require a lot of further effort in terms of isolation and characterization