CONTENT OF INVESTMENT ATTRACTIVENESS OF A REGION ECONOMY AS AN ECONOMIC CATEGORY

The article describes the concept of investment attractiveness. The main approaches to its determination are identified; the features of evaluation of investment attractiveness of a region economy are analysed

Inflammatory pain and corticosterone response in infant rats: effect of 5-HT1A agonist buspirone prior to gestational stress

Our researches have shown that gestational stress causes exacerbation of inflammatory pain in the offspring; the maternal 5-HT1A agonist buspirone before the stress prevents the adverse effect. The serotonergic system and hypothalamo-pituitary-adrenal (HPA) axis are closely interrelated. However, interrelations between inflammatory pain and the HPA axis during the hyporeactive period of the latter have not been studied. The present research demonstrates that formalin-induced pain causes a gradual and prolonged increase in plasma corticosterone level in 7-day-old male rats; twenty-four hours after injection of formalin, the basal corticosterone level still exceeds the initial basal corticosterone value. Chronic treatments of rat dams with buspirone before restraint stress during gestation normalize in the offspring pain-like behavior and induce during the acute phase in the formalin test the stronger corticosterone increase as compared to the stress hormonal elevation in animals with other prenatal treatments. Negative correlation between plasma corticosterone level and the number of flexes+shakes is revealed in buspirone+stress rats. The new data enhance the idea about relativity of the HPA axis hyporeactive period and suggest that maternal buspirone prior to stress during gestation may enhance an adaptive mechanism of the inflammatory nociceptive system in the infant male offspring through activation of the HPA axis peripheral link

The Formation of Indicator Framework for Effective Assessment of Investment Attractiveness of the Region

Despite the in-depth study of many theoretical aspects of investment activities and assessment of investment attractiveness, today the impact of the investment policy on the development of an effective strategy and the formation of favorable investment climate is not properly reflected in the contemporary research. At the same time unstable situation in socio-economic development of Russia requires new approaches to the problem of investment activity. In this regard, the article provides indicator framework to assess properly the investment attractiveness of the region's economy relating to foreign direct investment in the current context. At that, the proposed indicator framework is based on a number of principles, which allow achieving the objective assessment of investment attractiveness of regions and feasibility of the concerned indicators. Keywords: foreign direct investment, investment activity, investment climate, assessment of investment attractiveness, region's economy. JEL Classifications: F21; F51; H77; O2

СОДЕРЖАНИЕ ИНВЕСТИЦИОННОЙ ПРИВЛЕКАТЕЛЬНОСТИ ЭКОНОМИКИ РЕГИОНА КАК ЭКОНОМИЧЕСКОЙ КАТЕГОРИИ

The article describes the concept of investment attractiveness. The main approaches to its determination are identified; the features of evaluation of investment attractiveness of a region economy are analysed.В статье рассмотрен понятийный аппарат инвестиционной привлекательности, обосновываются основные подходы к определению инвестиционной привлекательности, анализируются особенности оценки инвестиционной привлекательности экономики региона

О СОДЕРЖАНИИ ЭКОНОМИЧЕСКОЙ КАТЕГОРИИ И ИЗМЕРЕНИИ РЫНОЧНОГО СПРОСА

The aim of the article is to study the economic and statistical categories and levels of consumer demand. There is no uniformity in the interpretation of the content of an economic category and demand level in the literature on the economic theory and applied research of the market. We want to conduct the verification of the demand category, a consolidation of the wording of measuring the level of demand, the classification of demand. Theoretical basis of the conducted research is the methodology of the economic theory and the general theory of statistics.Целью статьи является исследование экономико-статистической сущности категории и уровня потребительского спроса. В литературе по экономической теории и прикладным исследованиям рынка отсутствует единообразие в трактовке содержания экономической категории и уровня спроса. Требуется провести уточнение категории спроса, обобщение формулировок в части измерения уровня спроса, классификацию спроса. Теоретическую базу проведенного исследования составляет методология экономической теории и общей теории статистики

Long-term effects of chronic buspirone during adolescence reduce the adverse influences of neonatal inflammatory pain and stress on adaptive behavior in adult male rats

Neonatal pain and stress induce long-term changes in pain sensitivity and behavior. Previously we found alterations in pain sensitivity in adolescent rats exposed to early-life adverse events. We tested whether these alterations have long-lasting effects and if those effects can be improved by the 5-hydroxytryptamine 1A (5-HT1A) receptor agonist buspirone injected chronically during the adolescent period. This study investigates: (1) effects of inflammatory pain (the injection of formalin into the pad of a hind paw) or stress (short maternal deprivation-isolation, MI), or their combination in 1â\u80\u932-day-old rats on the adult basal pain, formalin-induced pain, anxiety and depression; (2) effects of adolescent buspirone in adult rats that experienced similar early-life insults. Changes in nociceptive thresholds were evaluated using the hot plate (HP) and formalin tests; levels of anxiety and depression were assessed with the elevated plus maze and forced swim tests respectively. Both neonatal painful and stressful treatments induced long-term alterations in the forced swim test. Other changes in adult behavioral responses were dependent on the type of neonatal treatment. There was a notable lack of long-term effects of the combination of early inflammatory pain and stress of MI on the pain responses, anxiety levels or on the effects of adolescent buspirone. This study provides the first evidence that chronic injection of buspirone in adolescent rats alters antinociceptive and anxiolytic effects limited to adult rats that showed behavioral alterations induced by early-life adverse treatments. These data highlight the role of 5-HT1A receptors in long-term effects of neonatal inflammatory pain and stress of short MI on adaptive behavior and possibility of correction of the pain and psychoemotional behavior that were altered by adverse pain/stress intervention using buspirone during critical adolescent period

ОЦЕНКА ЭФФЕКТИВНОСТИ УПРАВЛЕНИЯ ПОРТФЕЛЕМ ПАЕВОГО ИНВЕСТИЦИОННОГО ФОНДА

The article deals with the problem ofevaluating the effectiveness of portfolio of mutual fund management.В статье рассмотрен вопрос об оценке эффективностиуправленияпортфелем паевого инвестиционного фонда

ПРИНЦИПЫ ФОРМИРОВАНИЯ ИННОВАЦИОННОЙ МОДЕЛИ КОНТРОЛЯ НАД ЭФФЕКТИВНОСТЬЮ ИСПОЛЬЗОВАНИЯ БЮДЖЕТНЫХ СРЕДСТВ

The article describes the innovative approach to use of performance indicators to improve the quality of efficiency control of budget funds use, it is offered to create the inner budgetary administrative system of control on the effectiveness and appropriateness of the budgetary funds use.В статье рассмотрен инновационный подход по применению оценочных показателей для повышения качества контроля над эффективностью использования бюджетных средств, предлагается создать внутри бюджетную административную систему контроля по эффективности и целесообразности использования бюджетных средств

THE CONTENT OF AN ECONOMIC CATEGORY AND THE MEASUREMENT OF THE MARKET DEMAND

The aim of the article is to study the economic and statistical categories and levels of consumer demand. There is no uniformity in the interpretation of the content of an economic category and demand level in the literature on the economic theory and applied research of the market. We want to conduct the verification of the demand category, a consolidation of the wording of measuring the level of demand, the classification of demand. Theoretical basis of the conducted research is the methodology of the economic theory and the general theory of statistics