The comparison of rCBF between control and depression groups (Mean ±SEM, ml·min-1·100 g-1, n = 8).

<p>Note: Compared with control group * P&lt;0.05, ** P&lt;0.01.</p><p>rCBF: regional cerebral blood flow, ACA: anterior.</p><p>cerebral artery, MCA: middle cerebral artery.</p><p>PCA: posterior cerebral artery, L: Left, R: Right.</p><p>GM: gray matter, WM: white matter.</p><p>The comparison of rCBF between control and depression groups (Mean ±SEM, ml·min-1·100 g-1, n = 8).</p

The comparison of parameters of rCBFV between control and depression groups (Mean ± SEM, cm/s).

<p>Note: compared to the control group, *<i>P</i>&lt;0.05, **<i>P</i>&lt;0.01.</p><p>rCBFV: regional cerebral blood flow velocity.</p><p>MCA: middle cerebral artery, ACA: anterior cerebral artery.</p><p>PCA: posterior cerebral artery, TICA: the tip of internal carotid artery.</p><p>VA: vertebral artery, BA: basilar artery, L: Left, R: Right,</p><p>Vs: systolic peak velocity, Vm: mean flow velocity, Vd: diastolic velocity.</p><p>The comparison of parameters of rCBFV between control and depression groups (Mean ± SEM, cm/s).</p

The correlation coefficients between rCBF and rCBFV in depression group (n = 8).

<p>Note: The correlation coefficient t test * P&lt;0.05. ** P&lt;0.01.</p><p>rCBFV: regional cerebral blood flow velocity, rCBF: region cerebral blood flow.</p><p>ACA: anterior cerebral artery, MCA: middle cerebral artery, L: Left, R: Right.</p><p>Vs: systolic peak velocity, Vm: mean flow velocity, Vd: diastolic velocity.</p><p>The correlation coefficients between rCBF and rCBFV in depression group (n = 8).</p

The comparison of the values of PI between control and depression groups (Mean±SEM).

<p>Note: Compared with control group *P&lt;0.05, ** P&lt;0.01.</p><p>PI: Pulsatility index, ACA: anterior cerebral artery,</p><p>TICA: the tip of internal carotid artery, MCA: middle cerebral artery,</p><p>VA: vertebral artery, BA: basilar artery, L: Left, R: Right.</p><p>The comparison of the values of PI between control and depression groups (Mean±SEM).</p

The comparison of demographic data between control and depression groups (Mean ± SEM).

<p>Note: no significant differences in the demographic variables (age, sex, blood pressure, smoking) between two groups, SBP: systolic blood pressure, DBP: diastolic blood pressure.</p><p>The comparison of demographic data between control and depression groups (Mean ± SEM).</p

Regression equation between rCBFV and rCBF in depression group (n = 8).

<p>rCBFV: regional cerebral blood flow velocity, rCBF: region cerebral blood flow.</p><p>ACA: anterior cerebral artery, MCA: middle cerebral artery, L: Left, R: Right.</p><p>GM: gray matter, WM: white matter, Vs: systolic peak velocity, Vm: mean flow velocity.</p><p>Regression equation between rCBFV and rCBF in depression group (n = 8).</p

Case example: Coronal slices from dynamic CT angiography taken from a 44-year-old woman with depression.

<p>Circles represent regions of interest, with the mean ± SEM from 19 volume data presented. In MCA (middle cerebral artery) regions, the values of rCBF (regional cerebral blood flow) in left gray matter were lower than in the right [Left: 46.9 and 40.2 ml/(min·100 g),Right: 55.5 and 47.1 ml/(min·100 g)]. In PCA (posterior cerebral artery) regions, the values of rCBF in left gray matter were lower than in the right [Left: 30.2 ml/(min·100 g), Right: 47.8 ml/(min·100 g)].</p

The comparison of hemorheological parameters between depression and control groups (Mean ±SEM).

<p>Note: Compared with control group *<i>P</i>&lt;0.05, **<i>P</i>&lt;0.01.</p><p>The comparison of hemorheological parameters between depression and control groups (Mean ±SEM).</p

The comparison of demographic data between control and depression groups using the 320 slice CT (Mean ±SEM).

<p>Note: no significant differences in the demographic variables (age, sex, blood pressure, smoking) between two groups, SBP: systolic blood pressure, DBP: diastolic blood pressure.</p><p>The comparison of demographic data between control and depression groups using the 320 slice CT (Mean ±SEM).</p

Additional file 1: of The Post-Anaesthesia N-acetylcysteine Cognitive Evaluation (PANACEA) trial: study protocol for a randomised controlled trial

SPIRIT Checklist – PANACEA. (PDF 106 kb