123 research outputs found

    Normal spontaneous vaginal delivery

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    This issue of eMedRef provides information to clinicians on the indications of and procedures for a normal spontaneous vaginal delivery

    Secondary Causes of Obesity

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    Secondary causes of obesity can be detected by obtaining a patient history and performing a physical examination. Laboratory testing is recommended when additional findings are present, such as dysmorphic features, short stature, slow growth velocity, delayed puberty, or clinical signs and symptoms of endocrine abnormalities (e.g., hirsutism, truncal obesity, violaceous striae). (Strength of recommendation [SOR]: C, based on expert opinion.) Underlying metabolic and genetic causes of obesity are uncommon. The small number of children with a secondary cause of obesity typically also have short stature. (SOR: C, based on a prospective cohort study.

    Do nasal decongestants relieve symptoms?

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    Oral and topical nasal decongestants result in a statistically significant improvement in subjective symptoms of nasal congestion and objective nasal airway resistance in adults' common colds (strength of recommendation [SOR]: A, based on randomized controlled trials). Evidence is lacking to support the use of decongestants in acute sinusitis

    Complexity and diversity in c-type cytochrome biogenesis systems

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    Abstract c-type cytochromes contain haem covalently attached to protein by thioether bonds formed posttranslationally and requiring a dedicated biogenesis apparatus. Three biogenesis systems, found in different cell types, are well known. Here we discuss emerging evidence for at least one additional system, for unanticipated diversity in the location of the systems and for the co-existence of multiple systems in some cells

    Dyadic Interaction: Greater than the Sum of its Parts?

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    The study of dyadic interaction plays a major role in infancy research. To advance conceptually-informed measurement of dyadic interaction and integration across studies, we examined factor structure of individual parents’ and infants’ measures and dyadic measures from face-to-face interactions in two samples of 6-mo-old infants and their parents: mothers from a demographically heterogeneous sample (N = 164) and mothers and fathers (N = 156) from a Caucasian middle-class sample. Results suggested: a) individual and dyadic measures, and parents’ and infants’ behaviors contribute independent information, b) measures of both valence and process are needed, c) there are context-general and context-specific qualities, and d) structure of dyadic interaction is more similar among mother-infant dyads from independent samples than between mother- and father-infant dyads within the same sample. Future research should use multiple measures incorporating valence, temporal processes, contextual influences, and behaviors of individual partners along with dyadic measures to adequately assess the quality of dyadic interaction

    DNA-Coated AFM Cantilevers for the Investigation of Cell Adhesion and the Patterning of Live Cells

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    Measurement of receptor adhesion strength requires the precise manipulation of single cells on a contact surface. To attach live cells to a moveable probe, DNA sequences complementary to strands displayed on the plasma membrane are introduced onto AFM cantilevers (see picture, bp=base pairs). The strength of the resulting linkages can be tuned by varying the length of DNA strands, allowing for controlled transport of the cells

    The Gothic in Victorian Poetry

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    From Romantic Gothic to Victorian Medievalism: 1817 and 1877

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    "The Cambridge History of the Gothic was conceived in 2015, when Linda Bree, then Editorial Director at Cambridge University Press, first suggested the idea to us
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