11 research outputs found
La formación docente en momentos de cambios: ¿Qué nos dicen los profesores principiantes universiatrios?
Este estudio cualitativo con una metodología de estudios de casos múltiple examina la opinión de los profesores principiantes de la Universidad de Barcelona sobre las consecuencias del proceso de implementación del Espacio Europeo de Educación Superior (EEES). Indaga sobre la valoración que realiza el profesorado sobre la formación recibida en el postgrado de 'Iniciación a la docencia universitaria' y sobre los aprendizajes que les generó la experiencia formativa. La muestra de la investigación ha estado constituida por diez profesores principiantes de diferentes ámbitos de conocimiento de la Universidad de Barcelona y los datos proceden de la realización de entrevistas en profundidad. Entre los hallazgos más importantes, cabe destacar su percepción sobre la implementación del EEES y las propuestas que dan sobre los cambios que debería realizar la Universidad para una verdadera reforma de la formación de los docente
Findings in the human CSF samples.
<p>SRM ion chromatograms of A: standards (0.5 nM 5-HT and 5-HT-S, 10 nM DA-4- and 3-O-S and 100 nM HVA, 5-HIAA and 5-HIAA-S); B: a blank sample (Ringer’s solution); C-F: ventricular cerebrospinal fluid samples from patients 3–6; G: lumbar cerebrospinal fluid sample pooled from several patients.</p
Findings in the human brain microdialysis and the human cerebrospinal fluid samples.
<p>Findings in the human brain microdialysis and the human cerebrospinal fluid samples.</p
Validation results for all the compounds analyzed<b>.</b>
<p>Validation results for all the compounds analyzed<b>.</b></p
Main metabolic routes of serotonin and dopamine to their phase I metabolites.
<p>Main metabolic routes of serotonin and dopamine to their phase I metabolites.</p
Findings in the human brain microdialysis samples.
<p>SRM ion chromatograms of A: standards (1 nM 5-HT and 5-HT-G, 5 nM DA-3-O-S and HVA-O-G, 100 nM HVA, 5-HIAA and 5-HIAA-S); B: a blank sample (Ringer’s solution); C: a human brain microdialysis sample from patient 1; D: a human brain microdialysis sample from patient 2.</p
Five loci with a genome-wide significant association to saccular intracranial aneurysm (sIA) disease in the Finnish and Dutch samples.
*<p>For each variant minor allele/major allele, locus and base pair position are given.</p>**<p>The variant's distance (kb) to the nearest gene is given.</p>***<p>Located in the intron of the given gene.</p>†<p>The previously reported 9p21.3 locus <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004134#pgen.1004134-Yasuno2" target="_blank">[12]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004134#pgen.1004134-Helgadottir1" target="_blank">[39]</a>.</p>‡<p>The previously studied 2q33.3 locus with inconclusive evidence (see <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004134#s4" target="_blank">Materials and Methods</a>).</p>§<p>Some heterogeneity in effect sizes exists between cohorts. See <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004134#pgen.1004134.s015" target="_blank">Table S9</a> for heterogeneity statistics.</p
The Finnish and Dutch study samples used in the association analysis of saccular intracranial aneurysm (sIA) disease.
*<p>Unknown familial sIA status for 35 patients.</p>**<p>Number of sIAs not known for 16 patients.</p><p>SD = Standard deviation.</p
The locus with a genome-wide significant association to the number of saccular intracranial aneurysms (sIA) per individual in the Finnish samples.
*<p>For each variant major allele/minor allele, locus and base pair position are given.</p>**<p>Located in the intron of the given gene.</p>§<p>See <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1004134#pgen.1004134.s015" target="_blank">Table S9</a> for heterogeneity statistics.</p
Regional association plots of the five identified saccular intracranial aneurysm (sIA) loci in the combined Finnish samples and the Dutch sample.
<p>Association p-values (−log10 scale, y-axis) of variants are shown according to their chromosomal positions (x-axis). Blue lines indicate the genetic recombination rate (cM/Mb). Figures A–C present the loci identified in the case vs. control analysis at 2q23.3, 5q31.3, and 6q24.2, respectively. Figure D presents the 7p22.1 locus associated to the sIA count per patient. Figure E presents the 2q33.1 locus with inconclusive previous evidence. Purple rectangles indicate the most significant variant in a) the Finnish discovery sample and, along the dashed line, its p-values in b) the combined Finnish samples (META FIN) and in c) all samples (META ALL). Adjacent variants in linkage disequilibrium (r<sup>2</sup>; EUR populations, 1000 Genomes March 2012) to the index variant are shown in colours indicating their r<sup>2</sup> levels (r<sup>2</sup> box in each figure).</p