EVALUATION OF PHYSICOCHEMICAL STANDARDIZATION PARAMETERS OF SOLENA AMPLEXICAULIS LEAF

Solena amplexicaulis, commonly called as the creeping cucumber, belongs to the family Cucurbitaceae. Traditional it is used as astringent, appetizer, carminative, cardiotonic, digestive, diuretic, expectorant, invigorating, purgative and stimulant. Plant also having antioxidant antidiabetic and antibacterial action. The leaves showed potent anti-inflammatory activity.The present study was carried out to establish physico-chemical parameters along with preliminary phytochemical screening of petroleum ether, chloroform, methanolic and aqueous extracts of Solena amplexicaulis leaf. Preliminary phytochemical screening of various extracts revealed the presence of carbohydrate, alkaloids, flavonoids, sterols, phenolic & tannins compounds. The physico-chemical parameters such as total, water soluble, acid insoluble and sulphated ash (2.2, 1.9, 1.17 and 1.3%w/w respectively) and loss on drying (10.0 %w/w), extractive values foaming and swelling index were studied.   These studies will be helpful in developing standards for quality, purity and sample identification of this plant. Keyword: Standardization, Solena amplexicaulis, physicochemical and phytochemical

Retrospective-Cost-Based Adaptive State Estimation and Input Reconstruction for the Global Ionosphere-Thermosphere Model

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97110/1/AIAA2012-4601.pd

Retrospective-Cost Subsystem Identification for the Global Ionosphere-Thermosphere Model

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97111/1/AIAA2012-4602.pd

IN VITRO ANTIOXIDANT ACTIVITY OF DIFFERENT EXTRACTS OF CALENDULA OFFICINALIS LEAVES

Antioxidant activity of different extracts (water, alcohol and hydroalcohol) of Calendula officinalis leaves was studied for its free radical scavenging property on in vitro models as 1,1-diphenyl-2-picryl hydrazyl (DPPH ). The extract showed good dose-dependent free radical scavenging property. Hydro-alcoholic extract of Calendula officinalis leaves exhibited 82.58% inhibition by scavenging free radicals. In-vitro anti-oxidant studies of Calendula officinalis demonstrated the suppression of both inflammation and arthritis. The results indicate that the antioxidant property of the extract may be due to the high content of phenolic compounds. These results clearly indicate that Calendula officinalis is effective against free radical mediated disease. Keywords: Antioxidant, Calendula officinalis, Free radicals, Phenolic compound, Reductive ability

IN VITRO ANTIINFLAMMATORY ACTIVITY OF JUGLANS REGIA BARK

To evaluate the anti-inflammatory property of the different extract of bark of Juglans regia, family Juglandaceae is a deciduous tree. Its fruits are consumed as food, which are rich in unsaturated fatty acids. Walnut leaf has been widely used in traditional medicine for the treatment of skin inflammations and ulcers and for its antidiarrheic, antihelmintic, antiseptic and astringent properties. The present study aimed at the evaluation of anti-inflammatory property of the aqueous, chloroform and alcoholic extracts of the bark by in vitro methods. In vitro method was estimated by human red blood cell membrane stabilization (HRBC) method. Results showed significant anti-inflammatory property of the different extracts tested. The aqueous extract at a concentration of 200 mg/ml. showed potent activity on comparing with the standard drug diclofenac sodium. Key words: Juglans regia, HRBC, Inflammation and dicloenac.Â