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    Additional file 5: Figure S5. of Colitis susceptibility in p47 phox−/− mice is mediated by the microbiome

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    Heterozygous breeding decreases susceptibility to C. rodentium colitis in p47 phox−/− mice. Weight (A), histology score (colons isolated on day 12 post-infection) (B) and survival (C) plots of littermate p47phox−/− (n = 6) and B6Tac (n = 3) mice after infection with 5 × 109 CFU of C. rodentium. Bacterial load present in MLNs (D) and spleen (E) was determined on day 12 post-infection. Fecal loads of C. rodentium on day 12 post-infection are shown (F). Data are representative of two independent experiments. Significance was determined using the Mann-Whitney U test (*p < 0.05) and a log-rank test for survival (p = 0.16). (PPTX 199 kb
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