Evaluation of Oxidant and Antioxidant Systems in Drought Response of Cowpea Varieties

Plant in their natural environment are exposed to several stresses such as the drought that affect their growth and productivity. Exposure of plant to drought leads to oxidative stresses as a result of increase in ROS, however plant counteract this effect by its antioxidant system. H2O2, malondialdehyde, membrane stability index, catalase and ascorbate peroxidase activities where evaluated in leaves of two cowpea varieties drought tolerant (Dan’ila) and drought susceptible (TVU 7778) during 2 weeks water deficit and 5days recovery. The result indicates significant increase in the H2O2, MDA, CAT and APX activities in both varieties during the stress period and significant decrease during recovery in drought tolerant variety compared to the drought susceptible variety. The membrane stability index decreases significantly during stress period in both varieties. Drought tolerant variety has the higher ability to counteract oxidant activity during the drought stress and recover faster than the drought susceptible variety. Keywords: Drought, antioxidant, cowpea DOI: 10.7176/JNSR/12-8-03 Publication date: April 30th 202

Low dose bitter leaf improves sperm quality disrupted in immunosuppressed Wistar rats: An experimental study

Background: Synthetic prednisolone (PRED) is a widely used over-the-counter glucocorticoid. Glucocorticoids have inhibitory effects on the immune system and are often used as immunosuppressive agents. Suppressed immunity may impact fertility via the hypothalamic-pituitary-adrenal axis. Bitter leaf (BL) has been shown to improve sperm parameters, but its effects on immunosuppression-associated infertility have not yet been documented. Objective: To determine the fertility effects of bitter leaf on immunosuppressed Wistar rats. Materials and Methods: A total of 30 male adult Wistar rats were randomly assigned to 6 groups (n = 5/each). Group A served as a control and were given distilled water in addition to normal feeds, group B received 2 mg/kg PRED for 14 days and served as the standard immunosuppressed group, and groups C-F were immunosuppressed as in B but in addition received 50 mg/kg levamisole, low-dose (250 mg/kg) BL, highdose (375 mg/kg) BL, and low-dose BL + levamisole, respectively. The CD4 counts, hematological parameters, and sperm parameters were analyzed and compared. Results: There were significant decreases in sperm motility, progressive motility, morphology, and life/death ratio in the animals given PRED only compared to the controls (p = 0.002, 0.001, 0.001, and 0.01, respectively). These were significantly increased in the treated groups, and animals given levamisole and 250 mg/kg BL showed significantly increased sperm counts compared to the controls (p = 0.04 and p = 0.04, respectively). Conclusion: Low-dose BL (250 mg/kg) restored the sperm parameters altered by prednisolone administration. Key words: Bitter leaf, Immunosuppression, Infertility, Prednisolone, Rats

HERDPhobia: A Dataset for Hate Speech against Fulani in Nigeria

Social media platforms allow users to freely share their opinions about issues or anything they feel like. However, they also make it easier to spread hate and abusive content. The Fulani ethnic group has been the victim of this unfortunate phenomenon. This paper introduces the HERDPhobia - the first annotated hate speech dataset on Fulani herders in Nigeria - in three languages: English, Nigerian-Pidgin, and Hausa. We present a benchmark experiment using pre-trained languages models to classify the tweets as either hateful or non-hateful. Our experiment shows that the XML-T model provides better performance with 99.83% weighted F1. We released the dataset at https://github.com/hausanlp/HERDPhobia for further research.Comment: To appear in the Proceedings of the Sixth Workshop on Widening Natural Language Processing at EMNLP202

An Analysis of Relationship between Working Height and Productivity of Masonry Workers on Site

The analysed the relationship between working height and productivity of masonry worker on construction site by investigating two project sites. Data were also gathered by observing work activity on site. Time study form was design to record the various elements of the task performed and the time taken to complete each element over a period of observation at both floor levels for a period of six working days. A total of thirty structured questionnaires were administered on the factors affecting workers productivity on construction site. T-test was used to determine the difference between productivity at different level. The research concluded that the factors affecting\workers productivity are: Availability of materials, Weather, Gang size, Enabling environment, Height of work have strongly significant effect on the productivity of workers output on construction sites. A none statistically significant difference existed between the output of block laying at both floor levels but a statistically significant difference existed between the output of concrete work at first suspended floor slab and second suspended floor slab. It was also concluded that the output determined for Block laying was 12m2/day, Concrete work 19m2 /day and16m2 /day at 1st suspended and 2nd suspended floors respectively. It was recommended that the result of this research should be used to provide information upon which planning, scheduling and cost control of block laying, plastering and concrete works can be carried out.              Keywords: Construction Productivity, Work study, working height & Masonry productivit

Testicular morphology and seminal fluid parameters of adult Wistar rats following honey administration

Purpose: Honey has a long history of use in the traditional medical systems This objective of this study was to find out the effects of honey on quality and quantity of sperm and testicular microstructure when compared to fertility boosting drug and controls.Methods: A total number of thirty (30) matured male Wistar rats that were sexually active weighing 200 - 280g were used for this study. The animals were grouped into five as A - E. Group A was the control; Group B (standard group) was the standard group that received 0.3ml of follicle stimulating hormone (FSH) drug for 6 days; groups C, D and E received 1ml, 2ml, and 2.5ml of honey daily for 21days respectively. After 21 days of administration, the testes were removed for analysis of the sperm parameters and the histology.Results: Honey significantly improved the sperm quality and spermatogenesis rate (denser seminiferous tubule lumen) of exposed animals compared to control animals, but most improvement was seen in the standard group that received 0.3ml FSH. Also no sign of degeneration or cellular loss was observable in the testicular histo-architecture of experimental animals.Conclusion: This research showed that honey possesses some fertility boosting properties in exposed animals compared to controls and honey is not associated with increased sperm abnormalities.Keywords: Honey, Fertility booster, Spermatozoa, Ologospermi

Towards Universal Health Coverage in Africa: Relevance of Telemedicine and Mobile Clinics

Access to essential healthcare services is limited in Africa, resulting in preventable mortalities. Telemedicine, which can be defined as the use of information and communication technologies in the delivery of healthcare services, is applied in various fields of medicine and at multiple times. Some telemedicine projects have been implemented in different African countries. Some successes were recorded, as well as failures. Despite challenges, such as high cost, that inhibit telemedicine coverage, telemedicine still presents excellent opportunities in increasing access to basic healthcare and expert services. Mobile clinics provide the opportunity to expand access to health services across a region. They can be implemented as an extension of fixed1hospitals that are often situated away from remote villages, serve in the heart of communities, and aid in preventive screenings and epidemiological monitoring. Africa has limited resources but leveraging these existing resources most cost-effectively is key to achieving universal health coverage in the region. Source of funding: None Conflicting Interest: The authors declare no conflict of interest. Authors' Contributions: Oluwakorede Joshua Adedeji conceptualized the study. Oluwakorede Joshua Adedeji, Yusuf Olalekan Babatunde and Abdulmumin Damilola Ibrahim acquired, analysed and interpreted the data for the work. Yusuff Adebayo Adebisi and Don Eliseo Lucero-Prisno III revised it critically for important intellectual content. All authors agree to be accountable for all aspects of the work in ensuring that all questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved. &nbsp

Influence of Periodic Administration of Garlic Extract on Blood Parameters of Grazing Lambs

The study was carried out to investigate the effects of periodic  administration of garlic extract drench on haematology and serum biochemistry of grazing lambs. Twelve West African dwarf sheep with an average weight of 12.00 ±0.77 kg were allotted to 3 treatment groups with 4 animals per group in a completely randomized design which lasted for 10 weeks. Treatment 1 (T1) served as control with no garlic extract, Treatment (T2) were given 5ml garlic extract weekly and Treatment T3 received 5ml garlic extract every 2 weeks. Results of haematological analysis showed that PCV significantly (P<0.05) differs among treatment groups while RBC, MCV, WBC, LYM and GRA all show no significant (P>0.05) difference. The lowest PCV of 19.68% was observed in T1 while T2 recorded the highest PCV of 29.68%. The results from serum biochemical indices shows that cholesterol and ALT differ significantly (P<0.05) among treatment groups while total protein, albumin, globulin, glucose, urea and AST all show no significant (P>0.05) difference among treatment means. The lowest serum cholesterol value of 0.78 was observed in T2 while the control group  recorded the highest value of 1.30. The study suggests that garlic extract could be used to reduce the level of serum cholesterol in grazing lamb thereby improving meat quality.Keywords: Garlic Extract, West African Dwarf Sheep, Haematology, Biochemistry

Phytochemical Analysis and Acute Toxicity (LD50) Studies of Aqueous Seed Extract of Irvingia gabonensis (African mango)

African mango (Irvingia gabonensis) belongs to the Irvingiaceae family of plants, it has a long history both as a food and medicine. This study was carried out to analyze the phytochemicals of seed extract as well as to evaluate its acute oral toxicity (LD50). A total of thirteen rats were used for the acute toxicity study and was done in two phases; in phase I, nine rats were divided into three groups of three rats each and were orally administered with 10, 100 and 1000mg/kg body weight of the extract. The rats were observed for mortality and general behavior for 24hrs. In phase II, four rats were administered with the extract at higher doses of 1500, 2500, 3500 and 5000mg/kg respectively and were observed for mortality and other signs of toxicity for 24hrs. The results of the qualitative phytochemical analysis revealed the presence of alkaloids, flavonoids, glycoside, saponin, tannins, resins and reducing sugar with the absence of coumarin, while quantitative analysis shows that the extract is rich in glycosides, followed by flavonoids, followed by alkaloids, followed by saponin, and lastly tannin A and tannin B. Acute toxicity revealed that the extract was practically nontoxic with oral LD50 greater than 5000mg/kg body weight. In conclusion, these results showed that the extract is rich in phytochemicals and was found to be relatively safe at administered doses. Keywords: acute toxicity; Irvingia gabonensis; phytochemical analysis and seed extract. DOI: 10.7176/JBAH/9-24-07 Publication date: December 31st 201

Exploring the acceptability of Option B plus among HIV-positive Nigerian women engaged and not engaged in the prevention of mother-to-child transmission of HIV cascade: a qualitative study

The acceptability of lifelong antiretroviral therapy (ART) among HIV-positive women in highburden Nigeria, is not well-known. We explored readiness of users and providers of prevention of mother-to-child transmission of HIV (PMTCT) services to accept lifelong ART -before Option B plus was implemented in Nigeria. We conducted 142 key informant interviews among 100 PMTCT users (25 pregnant-newly-diagnosed, 26 pregnant-in-care, 28 lost-to-follow-up (LTFU) and 21 postpartum women living with HIV) and 42 PMTCT providers in rural North-Central Nigeria. Qualitative data were manually analyzed via Grounded Theory. PMTCT users had mixed views about lifelong ART, strongly influenced by motivation to prevent infant HIV and by presence or absence of maternal illness. Newly-diagnosed women were most enthusiastic about lifelong ART, however postpartum and LTFU women expressed conditionalities for acceptance and adherence, including minimal ART side effects and potentially serious maternal illness. Providers corroborated user findings, identifying the postpartum period as problematic for lifelong ART acceptability/adherence. Option B plus scale-up in Nigeria will require proactively addressing PMTCT user fears about ART side effects, and continuous education on long-term maternal and infant benefits. Structural barriers such as the availability of trained providers, long clinic wait times and patient access to ART should also be addressed.Keywords: Nigeria; HIV; adherence; Option B plus; PMTCT; rura

Analyzing COVID-19 Vaccination Sentiments in Nigerian Cyberspace: Insights from a Manually Annotated Twitter Dataset

Numerous successes have been achieved in combating the COVID-19 pandemic, initially using various precautionary measures like lockdowns, social distancing, and the use of face masks. More recently, various vaccinations have been developed to aid in the prevention or reduction of the severity of the COVID-19 infection. Despite the effectiveness of the precautionary measures and the vaccines, there are several controversies that are massively shared on social media platforms like Twitter. In this paper, we explore the use of state-of-the-art transformer-based language models to study people's acceptance of vaccines in Nigeria. We developed a novel dataset by crawling multi-lingual tweets using relevant hashtags and keywords. Our analysis and visualizations revealed that most tweets expressed neutral sentiments about COVID-19 vaccines, with some individuals expressing positive views, and there was no strong preference for specific vaccine types, although Moderna received slightly more positive sentiment. We also found out that fine-tuning a pre-trained LLM with an appropriate dataset can yield competitive results, even if the LLM was not initially pre-trained on the specific language of that dataset