23 research outputs found
Information from CTC measurements for metastatic breast cancer prognosis—we should do more than selecting an “optimal cut point”
Minimal residual disease and circulating tumor cells in breast cancer
Tumor cell dissemination in bone marrow or other organs is thought to represent an important step in the metastatic process. The detection of bone marrow disseminated tumor cells is associated with worse outcome in early breast cancer. Moreover, the detection of peripheral blood circulating tumor cells is an adverse prognostic factor in metastatic breast cancer, and emerging data suggest that this is also true for early disease. Beyond enumeration, the characterization of these cells has the potential to improve risk assessment, treatment selection and monitoring, and the development of novel therapeutic agents, and to advance our understanding of the biology of metastasis
Modeling the relationship between circulating tumour cells number and prognosis of metastatic breast cancer
No evidence for shedding of circulating tumor cells to the peripheral venous blood as a result of mammographic breast compression
International study on inter-reader variability for circulating tumor cells in breast cancer
External quality assurance of circulating tumor cell enumeration using the CellSearch(®) system: a feasibility study.
Circulating tumor cells (CTCs) are cells that have detached from solid tumors and entered the blood. CTCs can be detected, among others, by semi-automated immunomagnetic enrichment and image cytometry using CellSearch® (Veridex, Raritan, NJ). We studied the feasibility of external quality assurance (EQA) of the entire CellSearch procedure from blood draw to interpretation of results in multiple laboratories.info:eu-repo/semantics/publishe