Autological fibrin matrixs: Prospect surgery use

The article presents a technique for obtaining autologous carriers of tissue micrografts, or scaffolds, based on the interaction of fibrin and cells of the implanted material, as well as a method for the controlled production of autologous tissue matrices of the required volume, which are easily modeled. The processes of formation of a fibrin clot, its main physical characteristics have been investigated. The process of matrix gel compaction is considered, which significantly stimulates the attachment of tissue micrografts to the scaffold surface, which promotes metabolic processes. © 2021, Human Stem Cell Institute. All rights reserved

Results Of Orthotopic Bladder Creation After Radical Cystectomy In Patients With Bladder Cancer

This article presents the results of 116 radical cystectomies of patients with bladder cancer. In all the cases various generated modifications of orthotopic bladder including the authors' methodology have been carried out. The structure of complications during the post-operative period has been analyzed. Various complications occurred in 16,4 % of patients. In 3,4 % of cases they caused death. In 74% of cases direct dependence of postoperative complications on advanced tumorous process and severity of accomponied pathology has been identified. Direct dependence on the selection of method of urine derivation has not been found. Five-year cancer survival rate accounted 70 %. The study of patients' quality of life has been performed using EORTC-QLQ-C-30. High indices have been worked out. Dependence on the method of orthotopic bladder creation has been negligibl