Additional file 1. of Long-term outcomes and healthcare utilization following critical illness – a population-based study

Supplementary Figures and Tables. (DOC 204 kb

Additional file 1: of Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women

Statistical Analysis plan: KIR/HLA and viral control in seroconverters in CAPRISA 004 and CAPRISA050/051/HEPS. (DOCX 23 kb

Additional file 4: Figure S3. of Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women

Viral load measures according to HLA-types. . Each panel shows individual viral load or CD4+ T-cell count measures (dots) and LOWESS smoothed curve coloured according to HLA classification as protective, harmful or reference according to previous studies, with 95 % CI shown in grey shading. (PDF 1148 kb

Additional file 6: Figure S4. of Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women

Viral load (A-C) and CD4+ T-cell count (D-F) measures in KIR2DL2/KIR2DL2 (A, D), KIR2DL2/KIR2DL3 (B, E), KIR2DL3/KIR2DL3 (C, F) according to HLA-C1/HLA-C2 ligand grouping. Each panel shows individual viral load or CD4+ T-cell count measures (dots) and LOWESS smoothed curve coloured according to donor HLA C1/C2 allele groupings. (PDF 1822 kb

Additional file 3: Figure S2. of Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women

Cross-sectional viral load measures according to KIR haplotype. Boxes denote interquartile range (box margin) and median (solid line), and whiskers denote range. (PDF 1210 kb