Regulatory Proteolysis by N-Terminal Acetylation and the N-End Rule Pathway

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N-Terminal acetylation and formylation trigger protein degradation

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Synthetic lethal screen of NAA20, a catalytic subunit gene of NatB N-terminal acetylase in Saccharomyces cerevisiae

The Saccharomyces cerevisiae NatB N-terminal acetylase contains a catalytic subunit Nan20 and an auxiliary subunit Naa25. To elucidate the cellular functions of the NatB, we utilized the Synthetic Genetic Array to screen for genes that are essential for cell growth in the absence of NAA20. The genome-wide synthetic lethal screen of NAA20 identified genes encoding for serine/threonine protein kinase Vps15, 1,3-beta-glucanosyltransferase Gas5, and a catabolic repression regulator Mig3. The present study suggests that the catalytic activity of the NatB N-terminal aceytase is involved in vacuolar protein sorting and cell wall maintenance.

The Acetylation/N-End Rule and Arginine/N-End Rule Pathway

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Chlorobium limicola f. thiosulfatophilum 6430에서 순수분리한 SOD의 특성

학위논문(석사)--서울大學校 大學院 :微生物學科,1996.Maste

Functions and Mechanism of N-Terminal Acetylation and the N-End Rule proteolytic system

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The N-end rule pathway of the ubiquitin-mediated proteolysis

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The beginning mark the End: The N-End rule proteolytic pathway

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Control of G-protein signaling by the N-terminal Acetylation and the N-end Rule proteolytic system

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The beginning determines the End: The N-End rule proteolytic system

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