734 research outputs found

    Effects of dietary inclusion of various concentrations of Scutellaria baicalensis extract on growth, body composition, serum chemistry and challenge test of far eastern catfish (Silurus asotus)

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    Effects of various concentrations of Scutellaria baicalensis (SB) extract in the diets on growth, body composition, serum chemistry and challenge test of far eastern catfish (Silurus asotus) were determined and compared to commercially available immune enhancer. Eight experimental diets were prepared in triplicate: Con diet without supplementation of SB and SB-0.25, SB-0.5, SB-1, SB-2, SB-3 and SB-5 diets containing SB at the concentrations of 0.25, 0.5, 1, 2, 3 and 5%, respectively. In addition, 0.1% commercial product of immune enhancer was included into the diet (CP). At the end of the 8-week feeding trial, ten externally normal fish from each tank were infected by Vibrio anguillarum and Streptococcus iniae. No significant difference in weight gain of fish was found. Feed consumption, feed efficiency ratio and protein retention of fish was not affected by the experimental diets. Cumulative mortality of fish fed the Con diet was higher than that of fish fed the all other diets since 10 and 25 days after V. anguillarum and S. iniae infectionm 5. Results of this study indicated that dietary inclusion of SB extract was effective to improve survival of fish after V. anguillarum and S. iniae infection, but the various concentrations of SB did not affect fish performance.Contents = i List of Tables = ii List of Figures = iii Abstract (in Korean) = iv I. Experiment = 1 Abstract = 1 1. Introduction = 3 2. Materials and methods = 5 2.1. Experimental conditions = 5 2.2. Preparation of SB and the experimental diets = 5 2.3. Chemical analysis of the experimental diets and fish = 9 2.4. Chemical analysis of blood = 9 2.5. Challenge test = 10 2.6. Statistical analysis = 10 3. Results and discussion = 11 II. Conclusion = 26 III. Acknowledgements = 27 IV. References = 2

    Preparation of O-3 Polymer-based Piezoelectric Composites with (Pb_(1-x), Bi_x)(Ti_(1-y), Fe_y)O_(3) Powders

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    Piezoelectric materials are used extensively in many transducer applications. However they have limited utility in transducers used under hydrostatic conditions because of their low hydrostatic piezoelectric coefficient(d_h) have also limited utility in ultrasonic field due to small voltage coefficient(g₃₃) and large acoustic impedance. To improve the magnitude of hydrostatic piezoelectric coefficient and voltage coefficient, the composite of piezoelectric materials and polymer with different patterns have been prepared. In addition, these composites having lower acoustic impedance and smaller dielectric constant than those of solid piezoelectric materials, make it easier to obtain good impedance matching with water of the human body. Because of these advantages, piezoelectric composites would be used in many fields such as measuring instruments, diagnostic ultrasonic transducer, information processing instruments and acoustic devices. Especially, these composites have advantage of making a shape using ceramic powder that cannot produce by sintering. In this study, we produced the composites using (Pb_1-x, Bi_x)(Ti_1-y, Fe_y)O₃ powder which cannot produce by sintering because of its high tetragonality that create high inner stress. (Pb_1-x, Bi_x)(Ti_1-y, Fe_y)O₃/Epoxy 0-3 piezoelectric composites were prepared for investigating the effects of volume fraction of (Pb_1-x, Bi_x)(Ti_1-y, Fe_y)O₃ on the dielectric, piezoelectric properties of composites. (Pb_1-x Bi_x)(Ti_1-y Fe_y)O₃ powder, which has high tetragonality and voltage coefficient(g₃₃) was prepared from oxide mixture of PbO, Biβ‚‚O₃, TiOβ‚‚ and Feβ‚‚O₃. Then, (Pb_1-x, Bi_x)(Ti_1-y, Fe_y)O₃ particles were mixed with epoxy, piezoelectrically inactive species. After poling, dielectric, and piezoelectric properties were investigated.1. μ„œλ‘  = 1 2. 이둠적 λ°°κ²½ = 3 2.1 μ••μ „ 이둠 = 3 2.2 μ••μ „λ³΅ν•©μž¬λ£Œ = 5 2.2.1 세라믹-폴리머 λ³΅ν•©μ²΄μ˜ μ‘μš© = 5 2.2.2 λ³΅ν•©μ²΄μ˜ μ—°κ²°μ„± = 8 2.3 λ³΅ν•©μ†Œμž¬μ˜ μœ μ „νŠΉμ„±μ— λŒ€ν•œ 이둠 = 11 3. μ‹€ν—˜λ°©λ²• = 13 3.1 (Pb_1-x, Bi_x)(Ti_1-y, Fe_y)O₃ powder ν•©μ„± = 13 3.2 (Pb_1-x, Bi_x)(Ti_1-y, Fe_y)O₃/ polymer λ³΅ν•©μ²΄μ˜ 제쑰 = 17 3.3 μ „κ·ΉλΆ€μ°© 및 Hysteresis loop μΈ‘μ • = 20 4. κ²°λ‘  및 κ³ μ°° = 22 4.1 (Pb_1-x, Bi_x)(Ti_1-y, Fe_y)O₃ powder νŠΉμ„± = 22 4.2 (Pb_0.5, Bi_0.5)(Ti_0.5, Fe_0.5)O₃/ polymer λ³΅ν•©μ²΄μ˜ νŠΉμ„± = 27 5. κ²°λ‘  = 37 μ°Έκ³ λ¬Έν—Œ = 3

    Efficient Measurement System to Investigate Micro-Doppler Signature of Ballistic Missile

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    Micro-Doppler (MD) shift caused by the micro-motion of a ballistic missile (BM) can be very useful to identify it. In this paper, the MD signatures of three scale-model BMs are investigated using a portable measurement system. The measurement system consists of an X-band 2-by-2 phase comparison mono-pulse radar, and a mechanical device that can impart controlled spinning and coning motions simultaneously to a model to yield the MD signature that replicates the characteristic of each target and the corresponding micro-motion. The coning motion determined the overall period of MD, and the spinning motion increased its amplitude. MD was also dependent on aspect angle. The designed system is portable, and can implement many micro-motions; it will contribute to analysis of MD in various situations.110Ysciescopuskc

    A Study on the Improvement of Corrosion Resistance at Ship's Ballast Tank Steel Material by Effective Paintings and Hot-dip Coatings

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    졜근, μ „ μ„Έκ³„μ μœΌλ‘œ μ € νƒ„μ†Œ 녹색성μž₯ 산업이 뢀각 되고 μžˆλŠ” κΈ‰λ³€ν•˜λŠ” ν˜„μ‹€ μ†μ—μ„œ λŒ€λΆ€λΆ„μ˜ 선진ꡭ듀은 λ‹€μ–‘ν•œ λͺ¨λ“  μ‚°μ—…μœ‘μ„±μ„ μ§„ν–‰ν•˜κΈ°λ³΄λ‹€ 점점 자체적으둜 경쟁λ ₯ κ°•ν™”κ°€ μš°μ›”ν•œ 핡심 μ‚°μ—…λ§Œμ„ 쀑심 λ°œμ „μ‹œν‚€λ €λŠ” κ²½ν–₯으둜 μ§„ν™”λ˜κ³  μžˆλ‹€. 이에 따라 각 λ‚˜λΌμ˜ ν•„μš”λ‚˜ μˆ˜μš”μ— μ˜κ±°ν•˜μ—¬ κ΅­κ°€ μƒν˜Έκ°„μ˜ μˆ˜μž… λ˜λŠ” 수좜둜 μΈν•œ κ΅μ—­λŸ‰μ€ λ”μš± 더 μ¦λŒ€λ˜κ³  μžˆλŠ” 싀정이닀. 이와 같은 ꡐ역에 ν•„μš”ν•œ λ¬Όλ₯˜ μš΄μ†‘μ€ μ—¬λŸ¬ 가지 μš΄μ†‘ μˆ˜λ‹¨ 쀑 μ—­μ‹œ 경제적으둜 λ§Žμ€ ν™”λ¬Όμ˜ μš΄μ†‘μ„ κ°€λŠ₯ν•˜κ²Œ ν•˜λŠ” λŒ€ν˜•μ˜ 선박이 μ§€κΈˆκΉŒμ§€λŠ” λ¬Όλ‘  μ•žμœΌλ‘œλ„ 쀑좔적인 역할을 지속할 κ²ƒμœΌλ‘œ μ „λ§ν•˜κ³  μžˆλ‹€. λ”κ΅¬λ‚˜ 졜근 μ„ λ°•μ˜ μ΄ˆλŒ€ν˜•ν™”, κ³ μ†μš΄ν•­ν™”μ˜ μ‹€ν˜„κ³Ό λ”λΆˆμ–΄ λ¬Όλ₯˜μ‚°μ—…은 ν–₯후에도 λ”μš±λ” μ•ˆμ •μ μ΄κ³  ν˜Έν™©μ μΈ λΆ„μœ„κΈ°λ₯Ό μ „κ°œν•΄ λ‚˜κ°ˆ 수 μžˆμ„ κ²ƒμœΌλ‘œ μ˜ˆμƒλ˜κ³  μžˆλ‹€. ν•œνŽΈ, 이와 같은 λΆ„μœ„κΈ°μ™€ 달리 항상 κ°€ν˜Ήν•œ 뢀식 ν™˜κ²½μ— 놓여 μžˆλŠ” ν•΄μƒμ˜ μ„ λ°•μ—μ„œλŠ” μ’…μ’… λ‹€μ–‘ν•œ ν˜•νƒœμ˜ 손상사고 λ°œμƒμœΌλ‘œ κ·€μ€‘ν•œ 인λͺ…은 λ¬Όλ‘  λ§‰λŒ€ν•œ μž¬μ‚°μ˜ ν™”λ¬Ό 및 μ„ λ°•μ˜ μ•ˆμ „μ— μœ„ν—˜μ„ μ΄ˆλž˜ν•˜λŠ” κ³€λž€μ„ κ²ͺ기도 ν•œλ‹€. 이듀 쀑 특히 μ£Όλͺ©μ„ λ„λŠ” μ‚¬κ³ λ³΄κ³ λŠ” μš΄ν•­μ€‘μΈ μ„ λ°•μ˜ 밸러슀트 탱크 및 이쀑선츑 곡간 내뢀에 ν•΄μˆ˜κ΄€λ ¨ 뢀식에 κΈ°μΈν•œ λ¬Έμ œλ“€μ΄ 많이 λ°œμƒν•˜κ³  μžˆλ‹€λŠ” 것이닀(1). 일반적으둜 μ„ λ°•μ˜ 건쑰과정에 μžˆμ–΄μ„œ ν˜„μž¬κΉŒμ§€μ˜ κ°€μž₯ μœ νš¨ν•œ λ°©μ‹μˆ˜λ‹¨μ€ 도μž₯에 μ˜ν•΄ 피방식체인 선체λ₯Ό ν”Όλ³΅ν•˜λŠ” 방법이닀. ν•œνŽΈ μ΄λŸ¬ν•œ 도μž₯ν”Όλ³΅μ˜ κ²½μš°λŠ” λ‚΄κ΅¬μˆ˜λͺ…이 ν•œμ •λ˜μ–΄ μžˆμ–΄μ„œ 도μž₯ν‘œλ©΄μ΄ μ—¬λŸ¬ 가지 원인에 μ˜ν•΄ μ—΄ν™” λ˜λŠ” μ†μƒλ˜λŠ” κ²½μš°μ—λŠ” 뢀식이 κ°€μ†ν™”λ¨μœΌλ‘œ 인해 선체에 ꡬ쑰적인 λ¬Έμ œλ‚˜ νŒŒκ³΅λ˜λŠ” 사고 등이 λ°œμƒν•  수 μžˆλ‹€. κ·ΈλŸ¬λ‚˜ μ΄λŸ¬ν•œ 도μž₯ 방식법은 ν˜„μž¬κΉŒμ§€ ꡬ체적인 κ·œμ •μ΄ μ—†μŒμœΌλ‘œ μΈν•˜μ—¬ μ„ μ£Ό, μ‘°μ„ μ†Œ 및 λ„λ£ŒνšŒμ‚¬μ˜ ν˜‘μ˜μ— μ˜ν•œ κ²°μ •λ§ŒμœΌλ‘œ μž‘μ—… 및 검사가 μˆ˜ν–‰λ˜μ–΄ μ™”λ‹€. 이에 κ΅­μ œν•΄μ‚¬κΈ°κ΅¬(International Maritime Organization, IMO)μ—μ„œλŠ” μ΄λŸ¬ν•œ 도μž₯ λ°©μ‹λ²•μ˜ λ¬Έμ œμ μ„ ν•΄κ²°ν•˜κΈ° μœ„ν•˜μ—¬ κ΅­μ œν•΄μ‚¬κΈ°κ΅¬μ˜ μ‚°ν•˜μ‘°μ§μΈ ν•΄μƒμ•ˆμ „μœ„μ›νšŒλ₯Ό ν†΅ν•˜μ—¬ μ„ λ°•μ˜ 밸러슀트 탱크 및 이쀑 μ„ μΈ‘ 곡간에 λŒ€ν•œ λ³΄ν˜Έλ„μž₯ μ„±λŠ₯ κ·œμ • (PSPC : performance standard for protective coatings)을 2005년도에 μ œμ •ν•˜μ˜€κ³  2008년도뢀터 κ°•ν™”-μ‹œν–‰ν•˜κ³  μžˆλ‹€(2). 즉, κ΅­μ œν•΄μ‚¬κΈ°κ΅¬κ°€ μ œμ •ν•œ λ³΄ν˜Έλ„μž₯ μ„±λŠ₯κ·œμ •μ— μ˜ν•˜λ©΄, μ„ λ°•μ˜ 밸러슀트 νƒ±ν¬λ‚˜ 이쀑 μ„ μΈ‘ 곡간 등에 μ μš©ν•˜λŠ” 도μž₯의 수λͺ…을 15λ…„κ°„ μœ μ§€ 보μž₯ν•˜λ„λ‘ μš”κ΅¬ν•˜κ³  μžˆλ‹€. 이에 따라 μ„ μ£Όλ‚˜ μ‘°μ„ μ†Œλ“±μ˜ κ΄€λ ¨ κΈ°μ—…μ²΄μ—μ„œλŠ” κ·Έ μš”κ΅¬κ·œμ •μ„ λ‹¬μ„±ν•˜κΈ° μœ„ν•œ μ—¬λŸ¬ 가지 λ°©μ•ˆλ“€μ„ λ‹€κ°λ„λ‘œ κ²€ν† ν•˜κ³  μžˆλ‹€. 이에 λ³Έ μ—°κ΅¬μ—μ„œλŠ” μ„ λ°• λ°ΈλŸ¬μŠ€νŠΈνƒ±ν¬ κ΄€λ ¨ κ°•μž¬μ˜ 내식성을 λΆ€μ—¬ν•  λͺ©μ μœΌλ‘œ κ°•νŒμœ„μ— ν΄λ¦¬μ—ν‹Έλ Œ(PE : poly ethylene), ν΄λ¦¬μ•„λ―Έλ“œ (PA : poly amide), 순 μ—ν­μ‹œ(pure epoxy), μš©μœ΅μ•„μ—°λ„κΈˆ(hot-dip galvanized coating), μš©μœ΅μ•Œλ£¨λ―ΈλŠ„λ„κΈˆ (hot-dip aluminized coating)을 λ‹€μ–‘ν•œ λ°©λ²•μœΌλ‘œ μ‹€μ‹œν•˜μ—¬ μ—¬λŸ¬ 가지 μ’…λ₯˜μ˜ 막을 μ œμž‘ν•˜μ˜€λ‹€. 이와 같이 μ œμž‘ν•œ 막듀에 λŒ€ν•΄μ„œλŠ” ν•΄μˆ˜κ΄€λ ¨ ν™˜κ²½ 쀑 μ—¬λŸ¬ 가지 내식성 μ‹œν—˜-뢄석을 ν•˜μ—¬ κ·Έ 내식 νŠΉμ„±μ„ 비ꡐ 평가해 λ³΄μ•˜λ‹€. 즉, μ‚¬μš© ν™˜κ²½μ„ κ³ λ €ν•˜μ—¬ λ™μΌν•œ ν™˜κ²½μ‘°κ±΄ 쀑 각쒅 λ§‰μž¬λ£Œμ— λŒ€ν•œ 뢀식 κ²½ν–₯ 및 속도λ₯Ό 뢄석 μΆ”μ •ν•¨μœΌλ‘œμ¨ μ„ λ°• λ°ΈλŸ¬μŠ€νŠΈνƒ±ν¬ κ΄€λ ¨ κ°•μž¬μ˜ 내식성을 μœ„ν•œ μ œμž‘λ§‰μ˜ μ‚¬μš©μ€ λ¬Όλ‘  μ‘μš©μ„€κ³„μ— 기초적인 지침을 μ œμ‹œν•˜κ³ μž ν•˜μ˜€λ‹€.제 1 μž₯ μ„œλ‘  1 제 2 μž₯ 이둠적 λ°°κ²½ 3 2.1 κΈˆμ†μ˜ 뢀식 방식 κ°œμš” 3 2.1.1 κΈˆμ†μ˜ 뢀식 원리 3 2.1.2 κΈˆμ†λΆ€μ‹μ˜ μ’…λ₯˜ 10 2.1.3 κΈˆμ†μ˜ 방식법 13 2.1.4 λΆ€μ‹μ‹€ν—˜μ˜ μ’…λ₯˜ 및 평가 15 2.2 μ„ λ°• 도μž₯ 및 κ΅­μ œν•΄μ‚¬κΈ°κ΅¬ λ³΄ν˜Έλ„μž₯ μ„±λŠ₯κ·œμ • 20 2.2.1 μ„ λ°• 도μž₯의 λͺ©μ  20 2.2.2 μ„ λ°• 도μž₯의 방법 20 2.2.3 κ΅­μ œν•΄μ‚¬κΈ°κ΅¬ λ³΄ν˜Έλ„μž₯μ„±λŠ₯κ·œμ • ν˜‘μ•½ λ‚΄μš© 22 2.3 λ³Έ μ—°κ΅¬μš© μ„ μ • λ‚΄μ‹μ½”νŒ…μ˜ κ°œμš” 25 2.3.1 P.E 및 P.A μ½”νŒ…μ˜ κ°œμš” 25 2.3.2 μ—ν­μ‹œκ³„ 도μž₯의 κ°œμš” 30 2.3.3 용육 λ„κΈˆμ˜ κ°œμš” 32 제 3 μž₯ μ‹€ν—˜ 방법 44 3.1 P.E, P.A, 순 μ—ν­μ‹œ μ½”νŒ… 및 μš©μœ΅λ„κΈˆμ˜ μ œμž‘μ‘°κ±΄ 44 3.2 P.E, P.A, 순 μ—ν­μ‹œ μ½”νŒ… 및 용육 λ„κΈˆ λ§‰μ˜ 내식성 평가 49 3.2.1 μ „κΈ° 화학적 μ–‘κ·Ή λΆ„κ·Ή 및 μ •μ „μœ„ μ‹€ν—˜ 49 3.2.2 μ „κΈ° 화학적 μž„ν”Όλ˜μŠ€ 51 3.2.3 μžμ—° μ „μœ„ μΈ‘μ • 51 3.2.4 μ—Όμˆ˜ 뢄무 μ‹œν—˜ 52 제 4 μž₯ μ‹€ν—˜κ²°κ³Ό 및 κ³ μ°° 55 4.1 μ„ λ°•μ˜ 뢀식 ν˜„ν™©μ‘°μ‚¬ 55 4.2 P.E, P.A, 순 μ—ν­μ‹œ μ½”νŒ… 및 μš©μœ΅λ„κΈˆ λ§‰μ˜ μ œμž‘ κ²°κ³Ό 60 4.3 μ œμž‘ λ§‰μ˜ 전기화학적 λΆ„κ·Ή νŠΉμ„± 66 4.4 μ œμž‘ λ§‰μ˜ 전기화학적 μž„ν”Όλ˜μŠ€ νŠΉμ„± 72 4.5 μ œμž‘ λ§‰μ˜ μžμ—°μ „μœ„ μΈ‘μ • κ²°κ³Ό 77 4.6 μ œμž‘ λ§‰μ˜ μ—Όμˆ˜λΆ„λ¬΄ μ‹€ν—˜ κ²°κ³Ό 82 제 5 μž₯ κ²°λ‘  94 μ°Έκ³  λ¬Έν—Œ 96 κ°μ‚¬μ˜ κΈ€ 9

    Synthesis of fluorescent naphthalimide functionalized Fe3O4 nanoparticles and their application for the selective detection of Zn2+ present in contaminated soil

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    ν•™μœ„λ…Όλ¬Έ (석사)-- μ„œμšΈλŒ€ν•™κ΅ λŒ€ν•™μ› : κ±΄μ„€ν™˜κ²½κ³΅ν•™λΆ€, 2017. 2. λ°•μ€€λ²”.A fluorescent dopamine–naphthalimide–dipicolylamine (DPA) was synthesized as a sensing receptor for Zn2+. Naphthalimide-DPA (2) was immobilized onto the surface of iron oxide nanoparticle to prepare a hybrid nanomagnet 1-Fe3O4 for the purpose of selective detection of Zn2+ in soil. Naphthalimide–DPA (2) and 1-Fe3O4 were observed to bind with Zn2+, leading to significant increase in fluorescence intensity at 527 nm. The fluorescence increases of 2 (10 ΞΌM) and 1-Fe3O4 (0.33 wt%) by addition of Zn2+ were linear over the [Zn2+] range of 0–7 ΞΌM and 0–20 ΞΌM, respectively. These fluorescence changes were highly selective for Zn2+, which were readily monitored even in the presence of other competitive cations. In particular, 1-Fe3O4 exhibited an excellent limit of detection determined to be 0.0345 ppb. Furthermore, this system was found to be suitable for detecting Zn2+ in a wide pH range of 3–11 and could be reused with the addition of ethylenediaminetetraacetic acid (EDTA). Moreover, nanomagnet 1-Fe3O4 was employed for the selective detection and removal of Zn2+ from a soil sample. These results confirm that the use of 1-Fe3O4 is a novel and simple method for detecting Zn2+ in environmental samples.Chapter 1 Introduction 1 1.1 General 1 1.2 Outline 4 Chapter 2 Background 5 2.1 Background of the Fluorescence Chemosensor 5 2.1.1 Fluorecence 5 2.1.2 Photo-induced Electron Transfer 6 2.1.3 Chelation Enhanced Fluorescence 8 Chapter 3 Experimental Program 9 3.1 Materials and instruments 9 3.2 Spectroscopic methods 9 3.3 Detemination of limit of detection for 1-Fe3O4 10 3.4 Synthesis 11 3.4.1 Synthesis of iron-oleate complex 11 3.4.2 Synthesis of iron oxide nanocrystals 11 3.4.3 Synthesis of 1-Fe3O4 11 3.4.4 Synthesis of 1–5 13 3.4.5 Synthesis of 1 13 3.4.6 Synthesis of 2 16 3.4.7 Synthesis of 3 18 3.4.8 Synthesis of 4 21 3.5 Soil sampling, spiking, and extraction 24 Chapter 4 Experimental Results and Analysis 25 4.1 Synthesis and characterization of nanomagnet 1-Fe3O4 25 4.2 Spectroscopic analysis of the response of 2 to Zn2+ 29 4.2.1 Selectivity of 2 to Zn2+ 29 4.2.2 Zn2+ titration test of 2 34 4.2.3 pH titration test of 2 37 4.2.4 Reversibility test of 2 38 4.3 Spectroscopic analysis of the response of 1-Fe3O4 to Zn2+ 39 4.3.1 Selectivity of 1-Fe3O4 to Zn2+ 39 4.3.2 Response time of 1-Fe3O4 to Zn2+ 42 4.3.3 Zn2+ titration test of 1-Fe3O4 43 4.3.4 Reversibility test of 2 45 4.4 Detection of Zn2+ in soil samples 46 Chapter 5 Conclusions 48 Bibliography 49 초둝 54Maste

    VRK3-mediated inhibition of ERK signaling

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