サンカ ストレス ニヨリ ユウドウ サレル ナイブンピツ キノウ ヘンカ ニ タイスル ショウジュセン ノ エイキョウ

活性酸素種は老化を始めとして,糖尿病,発癌,アテローム硬化症などの生活習慣病の発症と深くかかわっていると考えられている.さらに,活性酸素種により内分泌障害も生じる可能性がある.一方,抗酸化物質は活性酸素種により引き起こされる様々な障害を予防することが知られている.我々は一般医薬品である松寿仙が強力な抗酸化活性を持つことをすでに示している.今回は,生体内でヒドロキシルラジカルを産生するferric nitrilotriacetate (FeNTA)により誘導される内分泌系の変化を松寿仙が保護するかどうかを調べることを目的にしてこの実験を行った.7週齢のWistar系雄ラットに飲料水に12.5%に含まれる松寿仙を12日間投与し, FeNTA (Fe, 7.5mg/kg)を腹腔内注射し, 12時間後に実験を行った.血中テストステロンはFeNTA投与により急速に低下したが,松寿仙前投与によりその低下が抑えられた.血中チロキシン値はFeNTAで低下したが,松寿仙はそれを正常化した.血中トリヨードチロニン値はFeNTAによっても松寿仙によっても何ら影響を受けなかった.血中コルチコステロンはFeNTAにより著しく増加したが,松寿仙はそれを正常化した.副腎のアスコルビン酸はFeNTAにより減少し,松寿仙により正常に復した.アスパラギン酸アミノ基転移酵素とアラニンアミノ基転移酵素および血清クレアチニンと尿素窒素はFeNTAにより上昇したが,松寿仙によりこれらの上昇はいずれにも正常とほぼ同じレベルまで戻った.以上の結果は,松寿仙はその中に含まれる生薬成分の抗酸化作用によりFeNTAで引き起こされた内分泌機能変化を保護することを示すものと考えられる.Reactive oxygen species (ROS) are involved in pathogenesis of various diseases, including senescence, diabetes mellitus, carcinoma and atherosclerosis. Endocrine disorders may also be induced by ROS. Antioxidants such as vitamin E and ascorbic acid have been shown to delay or prevent a variety of injuries caused by ROS. Our previous studies have shown that Shojusen acts as potent antioxidant in ROS-mediated disorders. The aim of our present study is to examine if Shojusen protects endocrine disturbances induced by ferric nitrilotriacetate (FeNTA) that generates hydroxyl radicals in vivo. Wistar rats of 7-week old were treated with or without 12.5 % Shojusen in drinking water for 12 d and FeNTA (7.5 mg/kg) was injected intraperitoneally 12 h before experiments. Serum testosterone decreased rapidly after FeNTA treatment, while Shojusen pretreatment prevented this fall in testosterone levels. Serum T_4 levels were decreased by FeNTA, while Shojusen restored the decreased levels to normal. Serum T_3 levels remained unchanged either by FeNTA or Shojusen. Serum corticosterone levels increased significantly following FeNTA treatment, while Shojusen reduced the increase levels to normal. Adrenal ascorbic acid was decreased by FeNTA and restored to normal by Shojusen. Serum levels of aminotransferases, creatinine and urea nitrogen were increased by FeNTA, while these parameters was normalized in Shojusen-pretreated rats. These results show that Shojusen prevents hydroxyl radical-mediated endocrine disorders induced by FeNTA by acting as an antioxidant

一种脉宽可调节的固体激光器

 本发明公开了一种脉宽可调节的固体激光器,该固体激光器包括依次按顺序共光轴地设置在一条直线上的泵浦源(1)、光束耦合系统(2)、激光晶体(3)、调Q晶体(4)和输出腔片(5)；其中,激光晶体(3)、调Q晶体(4)和输出腔片(5)构成谐振腔,激光晶体(4)是非各向同性晶体,调Q晶体(5)对激光具有偏振吸收的特性,通过转动该调Q晶体(5)的方向实现脉宽可调特性。本发明提供的脉宽可调节的固体激光器,结构简单可靠,体积小,操作方便,成本低廉,实用性强,有利于做出实际的产品

在具有Cu衬底层的Si（111）面上自组装Co团簇的研究

Nanodots as low dimensional surface structures exhibit interesting physical properties which can be exploited in numerous applications such as a single electron transistor, optoelectronic- and magnetic storage-devices etc. Since the top-down techniques used currently are reaching their limits, the bottom-up self-assembly is probably the most promising technique for the growth of nanoscale systems due to the striving of a system toward a minimal energy and the formation of nanosized structures down to the atomic level. Nevertheless, controlling and tailoring the size and distribution of these nanodotes for possible devices is a challenge and requires a thorough knowledge of the complex interaction between atoms and surface. Since cobalt is regarded as one of the most important elements used in magnetic materials for magnetic or magneto-optical devices and silicon is the key element used in the semiconductor industry, the combination of these two materials will promote the development of materials and devices for next-century magnetoelectronics. However, it is known that Co reacts easily with Si even at room temperature [1]. Nevertheless, recent works have shown that a buffer layer still strongly affects the surface diffusion of deposited atoms and the subsequent island nucleation [2-5]. Annealing of monolayer (ML) amounts of Cu on Si(111) leads to an (5.55×5.55) periodic reconstruction with excellent thermal stability. Although the Cu/Si(111) layer does not exhibit a true long range periodicity, its good stability, together with the significant removal of the Si dangling bonds, indicates that it is a good template for the fabrication of self-assembled Co nanoclusters. As far as we know, there are few studies of Co/Cu/Si(111) system. The present study provides the structural property of self-assembled Co nanoclusters on Cu/Si(111) surface using scanning tunneling microscopy (STM). STM and LEED results show that the Co nanolusters changes not only in the island size but also in the island shape and structures on the top of the islands with increasing substrate temperature from room temperature to 830K during deposition. It was confirmed that the ultrathin buffer layer on Si (111) surface has a significant influence on the surface morphology after subsequent depostiong of Co. On one hand it can partly prevent Co to form Co silicide. On the other hand the diffusion of Co atoms on the surface can be greatly enhanced. [1] J. M. Phillips, J. L. Batstone, J. C. Hensel, I. Wu. M. Cerullo, J. Mater. Res. 5, 1032 (1990). [2] X. Liu, T. Iimori, K. Nakatsuji, and F. Komori, Appl. Phys. Lett. 88, 133102 (2006). [3] T. Schmidt, J. I. Flege, S. Gangopadhyay, T. Clausen, A. Locatelli, S. Heun, and J. Falta, Phys. Rev. Lett. 98, 066104 (2007) [4] P. Aivaliotis, L. R. Wilson, E. A. Zibik, J. W. Cockburn, M. J. Steer, and H. Y. Liu, Appl. Phys. Lett. 91, 013503 (2007). [5] Y. Takagi, A. Nishimura, A. Nagashima, and J. Yoshino, Surf. Sci. 514, 167 (2002). Keywords: STM, Si surface, Co silicide, nanoclusters

伊犁河流域农牧交错带防护林营建技术研究及生态建设示范

1、项目的主要技术内容： ①选择流域重点区,进行林业生态示范工程建设。 ②开展优良树种选择和林农草优化组合配置试验,构建适宜当地的防护林建设技术集成模式。 ③进行人为干扰下的半荒漠草地恢复建设试验, 提出草地恢复措施。 ④进行伊犁河流域林业生态建设规划。 2、项目主要技术指标： ①流域重点防护林和林业生态建设试验示范技术指标： a、重点防护林和林业生态建设造林25000亩,其中核心示范区1500亩,林木成活率达到85﹪以上; b、选择适宜当地的优良树种; c、选择适宜当地水土保持型防护林结构配置技术; d、选择适宜当地草地恢复..

温性荒漠草地蒿类半灌木合理需水量探讨/Discussion on the rational water content for restoring semi - shrub Artemisia in desert grassland[J]

文中对新疆伊犁河流域温性荒漠草地蒿类半灌木生物量随水分条件的变化规律进行了研究。结果显不：随着灌溉水量的增加，单位面积蒿类生物量明显表现出先增加然后下降的变化规律。据灵敏度（Sk）计算，灌溉水量在433kg／（m^2·a）时，Sk存在最大值，表明此时地表生物量对灌溉水量变化的响应最为灵敏。根据灵敏度变化曲线将不同灌溉水量下地表生物量变化分为3个区间。灌溉水量在（226kg／（m^2·a）-778kg／（m^2·a））区间，蒿类生物量增加的幅度超过灌溉水量变化的幅度，实施此灌溉水量可得到最优恢复效果。因此恢复当地草地的合理水量范围确定在（226k/（m^2·a）-778kg／（m^2·a））。从水资源利用的效

不同胸径胡杨径向生长的合理生态水位研究[J]

借助树木年轮水文学的方法,分析不同胸径胡杨在不同地下水埋深条件下其径向生长量的变化特点和规律。研究结果表明:随着地下水埋深的增加,不同胸径胡杨径向生长量均呈现明显降低趋势,其对地下水埋深变化响应的灵敏度降低幅度呈现先增加,后减少的趋势。3个胸径等级的胡杨径向生长灵敏度最大值对应的地下水埋深为分别是3.3、7.4、7.9 m。说明,不同生长阶段的胡杨径向生长量变化对地下水埋深变化响应的敏感性存在差异。可以认为这3个地下水埋深是不同胸径等级胡杨径向生长水分胁迫的合理生态水位