Colector solar de placa plana de paso doble con lecho poroso

The use of hot air in various processes, requires the development of research to make more efficient and economical methods of producing, where the first option to be evaluated are the solar collectors. As this work develops a modeling of a flat plate solar collector and porous bed using analytical equations solving in block diagrams to structure a software that can simulate the behavior in transient state manifold under various parameters (dimensional, known materials and environmental conditions). In the application to theoretically evaluate the behavior of the porous bed, efficiency, pressure drop, temperature distribution and material used for construction, allowing analysis of the thermal behavior, with an average error compared to experimental results 6%. The model is validated experimentally, with data from an actual collector, where they remain an airflow of 0.119 kg / s and radiation varies between 400-500 W/m2 and observe the temperature distribution, thermal efficiency and falls pressure. In the results reach temperatures of 360 and 375 K in the exhaust air and pressure drops of 10.27 and 14.27 Pa, recording efficiency values of 36.5 and 51.7% respectively for radiation level. This fact demonstrates the suitability of such collectors as an option to capture solar energy.La utilización de aire caliente en diversos procesos hace necesario el desarrollo de investigaciones que hagan más eficientes y económicos los métodos de producirlo, donde la primera opción por evaluar son los colectores solares. Este trabajo desarrolla una modelación de un colector solar de placa plana y lecho poroso, empleando la solución de ecuaciones analíticas en diagramas de bloques, para estructurar un software que permite simular el comportamiento del colector en estado transitorio, bajo diversos parámetros. En la aplicación se evalúa teóricamente el comportamiento del lecho poroso, la eficiencia, la caída de presión, la distribución de temperaturas y los materiales empleados para su construcción. Esto permite un análisis del comportamiento térmico, con un error promedio comparado con resultados experimentales de 6 %. El modelo se valida experimentalmente, con datos de un colector real, donde se mantiene un flujo de aire de 0,119 kg/s y se varía la radiación entre 400 y 500 W/m2; se observa la distribución de temperaturas, la eficiencia térmica y las caídas de presión. En los resultados obtenidos se alcanzan temperaturas de 360 y 375 K en el aire de salida y caídas de presión de 10,27 y 14,27 Pa, con valores de eficiencia de 36,5 y 51,7%, respectivamente, para nivel de radiación. Esto demuestra la idoneidad de este tipo de colectores como una opción para captar energía solar

FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted

Understanding the molecular mechanisms involved in cholangiocarcinoma (bile duct cancer) development and progression stands as a critical step for the development of novel therapies. Through an inter-species approach, this study provides evidence of the clinical and functional role of the transcription factor FOSL1 in cholangiocarcinoma. Moreover, we report that downstream effectors of FOSL1 are susceptible to pharmacological inhibition, thus providing new opportunities for therapeutic intervention

Physical Activity Patterns of the Spanish Population Are Mostly Determined by Sex and Age: Findings in the ANIBES Study

Background Representative data for the Spanish population regarding physical activity (PA) behaviors are scarce and seldom comparable due to methodological inconsistencies. Aim Our objectives were to describe the PA behavior by means of the standardized self-reported International Physical Activity Questionnaire (IPAQ) and to know the proportion of the Spanish population meeting and not meeting international PA recommendations. Material and Methods PA was assessed using the IPAQ in a representative sample of 2285 individuals (males, 50.4%) aged 9–75 years and living in municipalities of at least 2,000 inhabitants. Data were analyzed according to: age groups 9–12, 13–17, 18–64, and 65–75 years; sex; geographical distribution; locality size and educational levels. Results Mean total PA was 868.8±660.9 min/wk, mean vigorous PA 146.4±254.1 min/wk, and mean moderate PA 398.1±408.0 min/wk, showing significant differences between sexes (p<0.05). Children performed higher moderate-vigorous PA than adolescents and seniors (p<0.05), and adults than adolescents and seniors (p<0.05). Compared to recommendations, 36.2%of adults performed <150 min/week of moderate PA, 65.4% <75 min/week of vigorous PA and 27.0%did not perform any PA at all, presenting significant differences between sexes (p<0.05). A total of 55.4%of children and adolescents performed less than 420 min/week of MVPA, being higher in the later (62.6%) than in the former (48.4%). Highest non-compliance was observed in adolescent females (86.5%). Conclusion Sex and age are the main influencing factors on PA in the Spanish population. Males engage in more vigorous and light PA overall, whereas females perform more moderate PA. PA behavior differs between age groups and no clear lineal increase with age could be observed. Twenty-seven percent of adults and 55.4% of children and adolescents do not meet international PA recommendations. Identified target groups should be addressed to increase PA in the Spanish populationCoca-Cola Iberia through Spanish Nutrition Foundation (FEN)Coca-Cola Iberi

Key Factors Associated With Pulmonary Sequelae in the Follow-Up of Critically Ill COVID-19 Patients

Introduction: Critical COVID-19 survivors have a high risk of respiratory sequelae. Therefore, we aimed to identify key factors associated with altered lung function and CT scan abnormalities at a follow-up visit in a cohort of critical COVID-19 survivors. Methods: Multicenter ambispective observational study in 52 Spanish intensive care units. Up to 1327 PCR-confirmed critical COVID-19 patients had sociodemographic, anthropometric, comorbidity and lifestyle characteristics collected at hospital admission; clinical and biological parameters throughout hospital stay; and, lung function and CT scan at a follow-up visit. Results: The median [p25–p75] time from discharge to follow-up was 3.57 [2.77–4.92] months. Median age was 60 [53–67] years, 27.8% women. The mean (SD) percentage of predicted diffusing lung capacity for carbon monoxide (DLCO) at follow-up was 72.02 (18.33)% predicted, with 66% of patients having DLCO < 80% and 24% having DLCO < 60%. CT scan showed persistent pulmonary infiltrates, fibrotic lesions, and emphysema in 33%, 25% and 6% of patients, respectively. Key variables associated with DLCO < 60% were chronic lung disease (CLD) (OR: 1.86 (1.18–2.92)), duration of invasive mechanical ventilation (IMV) (OR: 1.56 (1.37–1.77)), age (OR [per-1-SD] (95%CI): 1.39 (1.18–1.63)), urea (OR: 1.16 (0.97–1.39)) and estimated glomerular filtration rate at ICU admission (OR: 0.88 (0.73–1.06)). Bacterial pneumonia (1.62 (1.11–2.35)) and duration of ventilation (NIMV (1.23 (1.06–1.42), IMV (1.21 (1.01–1.45)) and prone positioning (1.17 (0.98–1.39)) were associated with fibrotic lesions. Conclusion: Age and CLD, reflecting patients’ baseline vulnerability, and markers of COVID-19 severity, such as duration of IMV and renal failure, were key factors associated with impaired DLCO and CT abnormalities

Vocabulario de la sociedad civil, la ruralidad y los movimientos sociales en América Latina

El Vocabulario de la Sociedad Civil, la Ruralidad y los Movimientos Sociales en América Latina tiene como objetivo desarrollar vocablos relacionados con temas de gran trascendencia para la vida colectiva de la población Latinoamericana; pretende introducir a estudiantes, personas del ámbito académico y activistas en la comprensión de estas categorías de análisis. A través de la mirada de 70 especialistas que participaron en este vocabulario, es posible comprender muchos de los términos que se utilizan dentro de la investigación social y áreas relacionadas con las ciencias políticas, ambientales y rurales, a partir de una mayor explicación y detalle. Es por ello que se inserta este trabajo desde una mirada colectiva y amplia de los conceptos que se exponen. En este libro podrá encontrar las ideas de varios autores y autoras de distintas universidades, con una visión multi, inter y transdisciplinaria. El esfuerzo que se realizó para conjuntar varios términos y analizar su compleja red de interpretaciones, permitirá que este manuscrito pueda ser consultado por estudiantes, personas del ámbito científico-académico, y ciudadanía; porque contiene el estado del arte, la historia del paulatino avance de múltiples conceptos y su vigencia en el contexto actual

Colector solar de placa plana de paso doble con lecho poroso

The use of hot air in various processes, requires the development of research to make more efficient and economical methods of producing, where the first option to be evaluated are the solar collectors. As this work develops a modeling of a flat plate solar collector and porous bed using analytical equations solving in block diagrams to structure a software that can simulate the behavior in transient state manifold under various parameters (dimensional, known materials and environmental conditions). In the application to theoretically evaluate the behavior of the porous bed, efficiency, pressure drop, temperature distribution and material used for construction, allowing analysis of the thermal behavior, with an average error compared to experimental results 6%. The model is validated experimentally, with data from an actual collector, where they remain an airflow of 0.119 kg / s and radiation varies between 400-500 W/m2 and observe the temperature distribution, thermal efficiency and falls pressure. In the results reach temperatures of 360 and 375 K in the exhaust air and pressure drops of 10.27 and 14.27 Pa, recording efficiency values of 36.5 and 51.7% respectively for radiation level. This fact demonstrates the suitability of such collectors as an option to capture solar energy.La utilización de aire caliente en diversos procesos hace necesario el desarrollo de investigaciones que hagan más eficientes y económicos los métodos de producirlo, donde la primera opción por evaluar son los colectores solares. Este trabajo desarrolla una modelación de un colector solar de placa plana y lecho poroso, empleando la solución de ecuaciones analíticas en diagramas de bloques, para estructurar un software que permite simular el comportamiento del colector en estado transitorio, bajo diversos parámetros. En la aplicación se evalúa teóricamente el comportamiento del lecho poroso, la eficiencia, la caída de presión, la distribución de temperaturas y los materiales empleados para su construcción. Esto permite un análisis del comportamiento térmico, con un error promedio comparado con resultados experimentales de 6 %. El modelo se valida experimentalmente, con datos de un colector real, donde se mantiene un flujo de aire de 0,119 kg/s y se varía la radiación entre 400 y 500 W/m2; se observa la distribución de temperaturas, la eficiencia térmica y las caídas de presión. En los resultados obtenidos se alcanzan temperaturas de 360 y 375 K en el aire de salida y caídas de presión de 10,27 y 14,27 Pa, con valores de eficiencia de 36,5 y 51,7%, respectivamente, para nivel de radiación. Esto demuestra la idoneidad de este tipo de colectores como una opción para captar energía solar