4,295 research outputs found

    Higgs-differential cross section at NNLO in dimensional regularisation

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    We present an analytic computation of the Higgs production cross section in the gluon fusion channel, which is differential in the components of the Higgs momentum and inclusive in the associated partonic radiation through NNLO in perturbative QCD. Our computation includes the necessary higher order terms in the dimensional regulator beyond the finite part that are required for renormalisation and collinear factorisation at N3^3LO. We outline in detail the computational methods which we employ. We present numerical predictions for realistic final state observables, specifically distributions for the decay products of the Higgs boson in the γγ\gamma\gamma decay channel.Comment: 27 pages, 6 awesome figure

    Academic medicine in Pavia

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    OVASI (Observatorio de Valores en la Sociedad Internacional.

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    Ante la necesidad de impulsar estudios científicos sociales que contengan una mirada ética crítica sobre los valores imperantes en la sociedad internacional, reconocemos como un problema global la existencia de una agenda selectiva (solamente aparecen a la luz aquellos ítems funcionales al poder) de temas internacionales, y teniendo en cuenta el trabajo que nos hemos dado estos últimos cinco años en proyectos sucesivos con idéntico carácter(tres de ellos con proyectos acreditados por el área de RSU del VRMU-UCC), se propone crear un programa denominado OVASI - Observatorio de Valores en la Sociedad Internacional, como la consecuencia lógica del trabajo desarrollado, y como la consolidación de un centro de atención de la dinámica mundial, instalado en la Facultad de Ciencia Política y Relaciones Internacionales de la Universidad Católica de Córdoba, que realice focos de atención en aquellos valores existentes (pero ocultos) en las relaciones políticas mundiales, desde la opción valórica de los más desfavorecidos. Desde nuestra concepción, la carencia de información y exclusión de inmensos sectores sociales desfavorecidos, son el espacio internacional en el cual encontramos una misión social como politólogos. La escasez de un respaldo intelectual, en el marco de la información y transmisión de conocimiento, es donde creemos que ayudaremos a las comunidades que carecen de estas herramientas de legitimación frente a los centros de poder

    One-loop QCD contributions to differential cross-sections for Higgs production at N3^3LO

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    We present one-loop contributions to the fully differential Higgs boson gluon-fusion cross-section for Higgs production via gluon fusion. Our results constitute a necessary ingredient of a complete N3^3LO determination of the cross-section. We perform our computation using a subtraction method for the treatment of soft and collinear singularities. We identify the infrared divergent parts in terms of universal splitting and eikonal functions, and demonstrate how phase-space integrations yield poles (up to 1/ϵ61/\epsilon^6 ) in the dimensional regulator ϵ=(4d)/2\epsilon=(4-d)/2. We compute the coefficients of the ϵ\epsilon expansion, including the finite part numerically. As a demonstration of our numerical implementation, we present the corrections at N3^3LO due to one-loop amplitudes in the rapidity and transverse momentum of the Higgs boson.Comment: 25 pages, 2 figure

    Extramedullary Disease in Acute Promyelocytic Leukemia: Two-In-One Disease

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    In acute promyelocytic leukemia (APL), extramedullary disease (EMD) is particularly rare and shows special clinical and biological features. It is estimated that about 3–5% of APL patients will suffer extramedullary relapse. The most common site of EMD in APL is the central nervous system (CNS). At present, there are still many issues of EMD in APL needing further clarification, including pathogenesis, risk factors, prognosis and treatment. A better understanding of the biological mechanisms underlying EMD is important to be able to devise more effective CNS prophylaxis and induction-consolidation therapeutic strategies

    Disinvestment in healthcare: An overview of HTA agencies and organizations activities at European level

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    Background: In an era of a growing economic pressure for all health systems, the interest for "disinvestment" in healthcare increased. In this context, evidence based approaches such as Health Technology Assessment (HTA) are needed both to invest and to disinvest in health technologies. In order to investigate the extent of application of HTA in this field, methodological projects/frameworks, case studies, dissemination initiatives on disinvestment released by HTA agencies and organizations located in Europe were searched. Methods: In July 2015, the websites of HTA agencies and organizations belonging to the European network for HTA (EUnetHTA) and the International Network of Agencies for HTA (INAHTA) were accessed and searched through the use of the term "disinvestment". Retrieved deliverables were considered eligible if they reported methodological projects/frameworks, case studies and dissemination initiatives focused on disinvestment in healthcare. Results: 62 HTA agencies/organizations were accessed and eight methodological projects/frameworks, one case study and one dissemination initiative were found starting from 2007. With respect to methodological projects/frameworks, two were delivered in Austria, one in Italy, two in Spain and three in U.K. As for the case study and the dissemination initiative, both came from U.K. The majority of deliverables were aimed at making an overview of existing disinvestment approaches and at identifying challenges in their introduction. Conclusions: Today, in a healthcare context characterized by resource scarcity and increasing service demand, "disinvestment" from low-value services and reinvestment in high-value ones is a key strategy that may be supported by HTA. The lack of evaluation of technologies in use, in particular at the end of their lifecycle, may be due to the scant availability of frameworks and guidelines for identification and assessment of obsolete technologies that was shown by our work. Although several projects were carried out in different countries, most remain constrained to the field of research. Disinvestment is a relatively new concept in HTA that could pose challenges also from a methodological point of view. To tackle these challenges, it is necessary to construct experiences at international level with the aim to develop new methodological approaches to produce and grow evidence on disinvestment policies and practices

    Isolation of Two Bacterial Species from Argan Soil in Morocco Associated with Polyhydroxybutyrate (PHB) Accumulation: Current Potential and Future Prospects for the Bio-Based Polymer Production

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    The environmental issues caused by the impacts of synthetic plastics use and derived wastes are arising the attention to bio-based plastics, natural polymers produced from renewable resources, including agricultural, industrial, and domestic wastes. Bio-based plastics represent a potential alternative to petroleum-based materials, due to the insufficient availability of fossil resources in the future and the affordable low cost of renewable ones that might be consumed for the biopolymer synthesis. Among the polyhydroxyalkanoates (PHA), the polyhydroxybutyrate (PHB) biopolymer has been synthesized and characterized with great interest due to its wide range of industrial applications. Currently, a wide number of bacterial species from soil, activated sludge, wastewater, industrial wastes, and compost have been identified as PHB producers. This work has the purpose of isolating and characterizing PHB-producing bacteria from the agricultural soil samples of Argania spinosa in the south region of Morocco where the plant species is endemic and preserved. During this research, four heat-resistant bacterial strains have been isolated. Among them, two species have been identified as endospore forming bacteria following the Schaffer-Fulton staining method with Malachite green and the Methylene blue method. Black intracellular granules have been appreciated in microscopy at 100× for both strains after staining with Sudan black B. The morphological and biochemical analyses of the isolates, including sugar fermentation and antibiotic susceptibility tests, preliminarily identified the strains 1B and 2D1 belonging to the genus Serratia and Proteus, respectivel

    Shakedown analysis for rolling and sliding contact problems

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    There is a range of problems where repeated rolling or sliding contact occurs. For such problems shakedown and limit analyses provides significant advantages over other forms of analysis when a global understanding of deformation behaviour is required. In this paper, a recently developed numerical method. Ponter and Engelhardt (2000) and Chen and Ponter (2001), for 3-D shakedown analyses is used to solve the rolling and sliding point contact problem previously considered by Ponter, Hearle and Johnson (1985) for a moving Herzian contact, with friction, over a half space. The method is an upper bound programming method, the Linear Matching Method, which provides a sequence of reducing upper bounds that converges to the least upper bound associated with a finite element mesh and may be implemented within a standard commercial finite element code. The solutions given in Ponter, Hearle and Johnson (1985) for circular contacts are reproduced and extended to the case when the frictional contact stresses are at an angle to the direction of travel. Solutions for the case where the contact region is elliptic are also given
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