6,395 research outputs found

    Supersymmetric NLO QCD Corrections to Resonant Slepton Production and Signals at the Tevatron and the LHC

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    We compute the total cross section and the transverse momentum distribution for single charged slepton and sneutrino production at hadronic colliders including NLO supersymmetric and non-supersymmetric QCD corrections. The supersymmetric QCD corrections can be substantial. We also resum the gluon transverse momentum distribution and compare our results with two Monte Carlo generators. We compute branching ratios of the supersymmetric decays of the slepton and determine event rates for the like-sign dimuon final state at the Tevatron and at the LHC.Comment: 14 pages, LaTeX, 8 figures, uses REVTex

    Stacked Micro Heat Exchange System for Optimized Thermal Coupling of MicroTEGs

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    This study presents modeling and experimental results of micro thermoelectric generators (μTEGs) integrated into a multilayer micro heat exchange system. The multilayer configuration benefits from low heat transfer resistances at small fluid flow rates and at the same time from low required pumping powers. The compact stacked power device allows for high net output power per volume, and therefore a reduction in size, weight, and cost compared with conventional large-scale heat exchangers. The influence of the boundary conditions and the system design parameters on the net output power of the micro heat exchange system was investigated by simulation. The theoretical results showed a major impact of the microchannel dimensions and the μTEG thickness on the overall output performance of the system. By adapting the applied fluid flow rate, the system's net power output can be maximized for varying operating temperatures. Experimental measurements of the cross-flow micro heat exchange system were in good agreement with the performed simulations. A net μTEG output power of 62.9mW/cm2 was measured for a double-layer system at an applied water inlet temperature difference of 60K with a Bi2Te3 μTEG (ZT of 0.12), resulting in a net volumetric efficiency factor of 37.2W/m3/K

    T. brucei cathepsin-L increases arrhythmogenic sarcoplasmic reticulum-mediated calcium release in rat cardiomyocytes

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    Aims: African trypanosomiasis, caused by Trypanosoma brucei species, leads to both neurological and cardiac dysfunction and can be fatal if untreated. While the neurological-related pathogenesis is well studied, the cardiac pathogenesis remains unknown. The current study exposed isolated ventricular cardiomyocytes and adult rat hearts to T. brucei to test whether trypanosomes can alter cardiac function independent of a systemic inflammatory/immune response. Methods and results: Using confocal imaging, T. brucei and T. brucei culture media (supernatant) caused an increased frequency of arrhythmogenic spontaneous diastolic sarcoplasmic reticulum (SR)-mediated Ca2+ release (Ca2+ waves) in isolated adult rat ventricular cardiomyocytes. Studies utilising inhibitors, recombinant protein and RNAi all demonstrated that this altered SR function was due to T. brucei cathepsin-L (TbCatL). Separate experiments revealed that TbCatL induced a 10–15% increase of SERCA activity but reduced SR Ca2+ content, suggesting a concomitant increased SR-mediated Ca2+ leak. This conclusion was supported by data demonstrating that TbCatL increased Ca2+ wave frequency. These effects were abolished by autocamtide-2-related inhibitory peptide, highlighting a role for CaMKII in the TbCatL action on SR function. Isolated Langendorff perfused whole heart experiments confirmed that supernatant caused an increased number of arrhythmic events. Conclusion: These data demonstrate for the first time that African trypanosomes alter cardiac function independent of a systemic immune response, via a mechanism involving extracellular cathepsin-L-mediated changes in SR function

    Protein kinase activation in theileria-infected cells

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    Inelastic production of J/ψ mesons in photoproduction and deep inelastic scattering at HERA

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    A measurement is presented of inelastic photo- and electroproduction of J/ψ mesons in ep scattering at HERA. The data were recorded with the H1 detector in the period from 2004 to 2007. Single and double differential cross sections are determined and the helicity distributions of the J/ψ mesons are analysed. The results are compared to theoretical predictions in the colour singlet model and in the framework of non-relativistic QCD. Calculations in the colour singlet model using a k T factorisation ansatz are able to give a good description of the data, while colour singlet model calculations to next-to-leading order in collinear factorisation underestimate the data

    Compact Frontend-Electronics and Bidirectional 3.3 Gbps Optical Datalink for Fast Proportional Chamber Readout

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    The 9600 channels of the multi-wire proportional chamber of the H1 experiment at HERA have to be read out within 96 ns and made available to the trigger system. The tight spatial conditions at the rear end flange require a compact bidirectional readout electronics with minimal power consumption and dead material. A solution using 40 identical optical link modules, each transferring the trigger information with a physical rate of 4 x 832 Mbps via optical fibers, has been developed and commisioned. The analog pulses from the chamber can be monitored and the synchronization to the global HERA clock signal is ensured.Comment: 13 pages, 10 figure

    Research Proposal for an Experiment to Search for the Decay {\mu} -> eee

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    We propose an experiment (Mu3e) to search for the lepton flavour violating decay mu+ -> e+e-e+. We aim for an ultimate sensitivity of one in 10^16 mu-decays, four orders of magnitude better than previous searches. This sensitivity is made possible by exploiting modern silicon pixel detectors providing high spatial resolution and hodoscopes using scintillating fibres and tiles providing precise timing information at high particle rates.Comment: Research proposal submitted to the Paul Scherrer Institute Research Committee for Particle Physics at the Ring Cyclotron, 104 page
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