1,715 research outputs found

    Innoveren door IT-outsourcing

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    in deze scriptie wordt verslag gedaan van een onderzoek naar de vraag op welke manier IT-outsourcing een bijdrage levert aan innoveren met IT. Daarnaast wordt er gekeken naar de eisen die gesteld kunnen worden aan de inrichting van de IT-outsourcingsovereenkomst

    Predictors for adherence to action plans for self-treatment of COPD exacerbations

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    Introduction/Aim: A minority of patients with chronic obstructive pulmonary disease (COPD) derives benefit fromself-management interventions that include action plans for self-treatment of COPD exacerbations. The aimof this studywas to identify predictors for adherence to action plans for self-treatment of exacerbations in COPD patients. Methods: Self-reported diary data from a subset of COPD patients who participated in a randomized controlled trial (COPE-II study) in the Netherlands was used to assess adherence to COPD action plans within a self-management intervention. Only patients with exacerbations were included. Successful self-treatment was defined as self-initiating a course of oral steroids/antibiotics within 2 days from the start of an exacerbation. A patient was defined as being adherent when in ≥75% of all exacerbations the self-treatment action plan was followed. Patient-level factors that showed a univariate association (P <0.10) with adherence were included in a multivariate logistic regression model to identify the predictors for adherence toCOPD self-treatment action plans (P <0.05). Results: Data from 66 patients (mean age 63.6 ± 8.0;men 56.1%) showed 387 exacerbations within 2 years of follow-up. Adherence to the action plans was observed in 37.9% of the patients and in 216 COPD exacerbations. Multivariate logistic regression analyses showed that being male (OR: 5.1; 95% CI: 1.5-17.3) and having no walking problems (EQ5D mobility, OR: 4.9; 95%CI: 1.5-16.4) were positively associatedwith being adherent to the action plan for self-treatment of COPD exacerbations. Conclusion: Our study results indicate that being male and having no walking problems are predictors for better adherence to COPD exacerbation action plans. This implies that exploring patients' mobility and offering more support to femaleCOPDpatients who are lessmobilemay positively influence the adherence to COPD exacerbation self-treatment action plans. More research is, however, required to confirm this

    Monitor moslimdiscriminatie:Derde rapportage

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    Dit is de derde rapportage van het Monitor Islamofobie Project, een meerjarig onderzoek dat wordt uitgevoerd door Dr. Ineke van der Valk, gastonderzoeker bij de afdeling Politicologie van de Universiteit van Amsterdam. Het Monitor Islamofobie Project rapporteert periodiek gegevens over moslimdiscriminatie en islamofobie in Nederland. Het longitudinale karakter van het project maakt het mogelijk om de ontwikkelingen rond dit verschijnsel over een langere periode te volgen en er daardoor beter inzicht in te krijgen. Per keer wordt op een deelonderwerp dieper ingegaan. In deze periode was dat de beeldvorming over moslims/islam op internet

    Post-traumatic cutaneous meningioma.

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    Cutaneous meningiomas are extremely rare tumours and their diagnosis is difficult. We describe the case of a patient who developed a paranasal swelling after head trauma and associated fractures in the same region years before. Histopathological examination of an incisional biopsy revealed the diagnosis of cutaneous meningioma. After one and a half years' follow up, surgical excision was performed because of progressive growth of the tumour and associated aesthetic problems. Extracranial meningiomas can develop probably secondary to trapping of meningeal tissue after trauma. If there is no intracranial connection surgical removal can be considered

    Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis

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    PMCID: PMC3856490This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.PMCID: PMC385649
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