Proxy measurements in Multiple Sclerosis

Polman, C.H. [Promotor]Ploeg, H.M. van der [Promotor]Uitdehaag, B.M.J. [Copromotor]Klein, M. [Copromotor

Toward the use of proxy reports for estimating long-term patient-reported outcomes in multiple sclerosis

BACKGROUND: Assessment of disease impact in multiple sclerosis (MS) is usually driven by information obtained directly from patients using patient-reported outcomes. However, when patients' response in longitudinal studies is less reliable or missing, proxy respondents may be used