3 research outputs found
Determining the Severity of Atopic Dermatitis in Children Presenting in General Practice: An Easy and Fast Method
Assessment of the
severity of atopic dermatitis (AD) is necessary
to evaluate the disease process. This study
evaluates and validates the TIS in children with
AD presenting in general practice. Independent
investigators determined the severity of AD
using the TIS and the objective SCORAD. The
interobserver agreement for the TIS and SCORAD
was calculated, as was the correlation between
TIS and SCORAD. The mean time to assess the TIS
was less than one minute. A moderate-to-good
agreement between the observers was found for
the TIS (Îș = 0.604 or 0.464), or SCORAD (Îș = 0.695 or 0.700). There was an excellent correlation between TIS and SCORAD (rs = 0.755â0.839). In conclusion, the TIS is an easy and fast method to
score AD. Because of the moderate to good interobserver agreement
and the high correlation with the SCORAD, we recommend the TIS to
determine the severity of AD in general practice
Quality of life measurement and its relationship to disease severity in children with atopic dermatitis in general practice
Atopic dermatitis (AD) has a big impact on quality of life. The usefulness of health-related quality of life questionnaires for children with AD in general practice, and the relationship of quality of life to disease severity, as assessed by parents and by investigators, however, is not known. This study used the Infants' Dermatitis Quality of Life Index (IDQoL) to assess quality of life in children with AD selected from general practice. Severity of AD was determined by investigators and parents using the objective SCORAD (SCORing Atopic Dermatitis), the TIS (three-item severity scale), or by an additional question on the IDQoL. A total of 66 patients (41% boys, mean age 31 months) were included. Correlations between disease severity assessed by parents and by investigators were low (Rs 0.29-0.51). Correlations between IDQoL and severity assessed by investigators were also low (Rs 0.08-0.36). However, correlations between IDQoL and severity according to parents were high (Rs 0.67-0.73). In conclusion, disease severity and disease-related quality of life are different aspects of AD and must be taken into consideration when evaluating treatment or investigating new dermatological therapies in trials
doi:10.1155/2009/357046 Research Article Determining the Severity of Atopic Dermatitis in Children Presenting in General Practice: An Easy and Fast Method
Assessment of the severity of atopic dermatitis (AD) is necessary to evaluate the disease process. This study evaluates and validates the TIS in children with AD presenting in general practice. Independent investigators determined the severity of AD using the TIS and the objective SCORAD. The interobserver agreement for the TIS and SCORAD was calculated, as was the correlation between TIS and SCORAD. The mean time to assess the TIS was less than one minute. A moderate-to-good agreement between the observers was found for the TIS (Îș = 0.604 or 0.464), or SCORAD (Îș = 0.695 or 0.700). There was an excellent correlation betweenTISandSCORAD(rs = 0.755â0.839). In conclusion, the TIS is an easy and fast method to score AD. Because of the moderate to good interobserver agreement and the high correlation with the SCORAD, we recommend the TIS to determine the severity of AD in general practice. Copyright © 2009 Marjolein G. Willemsen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 1