Physical activity, immobilization and the risk of venous thrombosis

Deep venous thrombosis is a common disease. Already in 1856 it was suggested that immobilization could cause venous thrombosis. However, so far little research has shown whether exercise or ambulation could decrease the risk of venous thrombosis. We performed a historical review regarding the role of venous thrombosis risk in the change of the practices regarding ambulation after delivery. We could not find well-performed studies showing that early ambulation reduced venous thrombosis risk. Furthermore we performed two studies on the relation between participating in physical activity and venous thrombosis risk. In one case-control study in the Netherlands we showed that exercise decreases the risk of venous thrombosis. However, in a cohort study in elderly people from the USA, we showed that exercise seemed to increase this risk. A possible explanation for this difference might be due to an increased risk of injuries among elderly people as we showed that injuries increase the risk of venous thrombosis 5 fold. Furthermore we showed that for the very rare thrombosis of the arm, sports activities which highly involve the arm result in an increased risk. In summary, although immobilization seems to increase venous thrombosis risk, it is unclear whether mobilization or exercise decrease this risk.de Nederlandse Hartstichting J.E. Jurriaanse Stichting Roche Diagnostics Bayer Health CareUBL - phd migration 201

Inventarisatie van het sublitorale wilde mosselbestand in de westelijke Waddenzee in het voorjaar van 2010

In de Waddenzee wordt sinds 1992 jaarlijks in het voorjaar en in het najaar het wilde mosselbestand geïnventariseerd. De bestandsopnamen vormen de basis voor het visserijbeleid en voor de visplannen van de sector voor de mosselvisserij. De bestandsopnamen zijn daarnaast een belangrijke bron van informatie voor ecosysteem- en effectstudies zoals het PRODUS-onderzoek (IMARES, 2007) en voor de uitvoering van het Convenant Transitie Mosselvisserij (LNV, 2008-a, PvU, 2010).Voorliggend rapport behandelt de inventarisatie van het wilde mosselbestand in het sublitoraal van de westelijke Waddenzee in het voorjaar van 2010. Daarbij zijn bestandsschattingen gemaakt en zijn potentiële vangsten in de voor visserij toegankelijke gebieden berekend

Use of national and international growth charts for studying height in european children: Development of up-to-date european height-for-age charts

Background: Growth charts based on data collected in different populations and time periods are key tools to assess children's linear growth. We analyzed the impact of geographic factors and the secular trend on height-for-age charts currently used in European populations, developed up-to-date European growth charts, and studied the effect of u

Patients want to be seen: The top 3 information needs of patients with inguinal hernia.

Background Good patient information has shown to improve surgical outcomes. In this study we explore what kind of pre-surgical information patients need and if the provision of a 360˚ video of a surgical procedure can be of added value to the information provided by the hospital. Methods An explorative qualitative study using semi-structured interviews on information needs was conducted among 17 inguinal hernia patients to gain more insight in the patients’ present surgical information needs. Patients either were planned to receive or already had received a surgical procedure. Questions were asked about the current informatio

Considerable variations in growth hormone policy and prescription in paediatric end-stage renal disease across European countries—a report from the ESPN/ERA-EDTA registry

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Case-Control Studies - An Efficient Observational Study Design

Case-control studies are an efficient research method for investigating risk factors of a disease. The method involves the comparison of the odds of exposure in a patient group with that of the odds of exposure in a control group. As only a minority of the population is included in the study, less time can be devoted to those who remain free of the disease of interest. The design of a case-control study can be complex due to the selection of the appropriate cases and controls. Cases can be identified in a prospective and retrospective manner from various sources. Controls can be obtained via the patient, random digit dialing or in a hospital and all at different points in the time period of the study. All options have their own advantages and disadvantages. Furthermore, different forms of bias, such as recall bias and selection bias, can occur. When appropriately designed, case-control studies can provide the same information as in a cohort study, in a more rapid and efficient manner. Copyright (C) 2009 S. Karger AG, Base

Measuring Agreement, More Complicated Than It Seems

Clinical epidemiolog