1,561 research outputs found

    “Cross-editing”: Comparing News Output Through Journalists’ Re-working of Their Rivals’ Scripts

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    Newsdesk journalists make thousands of editorial decisions every day without recourse to style guides. They can do this because they have internalised the aims and values of their news organisations: they know what counts as a “good story” for their output. This paper describes a pioneering micro-level comparative method of studying journalistic values in which, unlike in other comparative studies, the journalists themselves perform the initial analysis. In essence, newsdesk editors from two news organisations swap scripts. They evaluate, edit and mark up their rivals’ texts as if they were being asked to use them in their own output. What would they alter, insert or leave out? Would they reject a story completely? This “cross-edit” and the editors’ additional observations represent unmediated analysis from inside the news editing process, allowing researchers to draw comparative conclusions grounded principally in discourse analysis. To pilot the method, a number of journalists from the BBC and China’s official English-language news provider, CCTV-News (now CGTN), cross-edited selected news scripts published by their rivals. The technique shed new light on news routines, lexical choices, omissions and unexpected consonances in news values. It was then refined to provide a framework for future, wider use

    Iterative algorithms for total variation-like reconstructions in seismic tomography

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    A qualitative comparison of total variation like penalties (total variation, Huber variant of total variation, total generalized variation, ...) is made in the context of global seismic tomography. Both penalized and constrained formulations of seismic recovery problems are treated. A number of simple iterative recovery algorithms applicable to these problems are described. The convergence speed of these algorithms is compared numerically in this setting. For the constrained formulation a new algorithm is proposed and its convergence is proven.Comment: 28 pages, 8 figures. Corrected sign errors in formula (25

    Angular momentum transport and turbulence in laboratory models of Keplerian flows

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    We present angular momentum transport (torque) measurements in two recent experimental studies of the turbulent flow between independently rotating cylinders. In addition to these studies, we reanalyze prior torque measurements to expand the range of control parameters for the experimental Taylor-Couette flows. We find that the torque may be described as a product of functions that depend only on the Reynolds number, which describes the turbulent driving intensity, and the rotation number, which characterizes the effects of global rotation. For a given Reynolds number, the global angular momentum transport for Keplerian-like flow profiles is approximately 14% of the maximum achievable transport rate. We estimate that this level of transport would produce an accretion rate of M˙/M0˙103\dot{M}/\dot{M_0} \sim 10^{-3} in astrophysical disks. We argue that this level of transport from hydrodynamics alone could be significant.Comment: 17 pages, 7 figures, 2 tables, submitted to Astronomy & Astrophysics (2011

    Clonal karyotype evolution involving ring chromosome 1 with myelodysplastic syndrome subtype RAEB-t progressing into acute leukemia

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    s Karyotypic evolution is a well-known phenomenon in patients with malignant hernatological disorders during disease progression. We describe a 50-year-old male patient who had originally presented with pancytopenia in October 1992. The diagnosis of a myelodysplastic syndrome (MDS) FAB subtype RAEB-t was established in April 1993 by histological bone marrow (BM) examination, and therapy with low-dose cytosine arabinoside was initiated. In a phase of partial hernatological remission, cytogenetic assessment in August 1993 revealed a ring chromosome 1 in 13 of 21 metaphases beside BM cells with normal karyotypes {[}46,XY,r(1)(p35q31)/46,XY]. One month later, the patient progressed to an acute myeloid leukemia (AML), subtype M4 with 40% BM blasts and cytogenetic examination showed clonal evolution by the appearance of additional numerical aberrations in addition to the ring chromosome{[}46,XY,r(1),+8,-21/45,XY,r(1),+8,-21,-22/46, XY]. Intensive chemotherapy and radiotherapy was applied to induce remission in preparation for allogeneic bone marrow transplantation (BMT) from the patient's HLA-compatible son. After BMT, complete remission was clinically, hematologically and cytogenetically (normal male karyotype) confirmed. A complete hematopoietic chimerism was demonstrated. A relapse in January 1997 was successfully treated using donor lymphocyte infusion and donor peripheral blood stem cells (PB-SC) in combination with GM-CSF as immunostimulating agent in April 1997, and the patient's clinical condition remained stable as of January 2005. This is an interesting case of a patient with AML secondary to MDS. With the ring chromosome 1 we also describe a rare cytogenetic abnormality that predicted the poor prognosis of the patient, but the patient could be cured by adoptive immunotherapy and the application of donor's PB-SC. This case confirms the value of cytogenetic analysis in characterizing the malignant clone in hernatological neoplasias, the importance of controlling the quality of an induced remission and of the detection of a progress of the disease. Copyright (c) 2006 S. Karger AG, Basel

    Asymmetric Bethe-Salpeter equation for pairing and condensation

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    The Martin-Schwinger hierarchy of correlations are reexamined and the three-particle correlations are investigated under various partial summations. Besides the known approximations of screened, ladder and maximally crossed diagrams the pair-pair correlations are considered. It is shown that the recently proposed asymmetric Bethe-Salpeter equation to avoid unphysical repeated collisions is derived as a result of the hierarchical dependencies of correlations. Exceeding the parquet approximation we show that an asymmetry appears in the selfconsistent propagators. This form is superior over the symmetric selfconsistent one since it provides the Nambu-Gorkov equations and gap equation for fermions and the Beliaev equations for bosons while from the symmetric form no gap equation results. The selfenergy diagrams which account for the subtraction of unphysical repeated collisions are derived from the pair-pair correlation in the three-particle Greenfunction. It is suggested to distinguish between two types of selfconsistency, the channel-dressed propagators and the completely dressed propagators, with the help of which the asymmetric expansion completes the Ward identity and is Φ\Phi-derivable.Comment: 12 pages. 26 figure

    Image-guided focused ultrasound ablation of breast cancer: current status, challenges, and future directions

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    Image-guided focussed ultrasound (FUS) ablation is a non-invasive procedure that has been used for treatment of benign or malignant breast tumours. Image-guidance during ablation is achieved either by using real-time ultrasound (US) or magnetic resonance imaging (MRI). The past decade phase I studies have proven MRI-guided and US-guided FUS ablation of breast cancer to be technically feasible and safe. We provide an overview of studies assessing the efficacy of FUS for breast tumour ablation as measured by percentages of complete tumour necrosis. Successful ablation ranged from 20% to 100%, depending on FUS system type, imaging technique, ablation protocol, and patient selection. Specific issues related to FUS ablation of breast cancer, such as increased treatment time for larger tumours, size of ablation margins, methods used for margin assessment and residual tumour detection after FUS ablation, and impact of FUS ablation on sentinel node procedure are presented. Finally, potential future applications of FUS for breast cancer treatment such as FUS-induced anti-tumour immune response, FUS-mediated gene transfer, and enhanced drug delivery are discussed. Currently, breast-conserving surgery remains the gold standard for breast cancer treatment
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