Kennisbasis WOT Fisheries 2011 - what is in the Programme?

The KBWOT Fisheries programme is core to the maintenance and development of the expertise that underpins the statutory obligations of fisheries monitoring and advice for the Netherlands. The structure of the KBWOT Fisheries programme for 2011 changed to reflect the recent discussions on the research direction between IMARES, CVO and EL&I. One of the strengths of the structure of the KBWOT Fisheries programme was the bottom up approach to calls for projects to fulfil the research priorities. This however was seen as giving the programme the potential to miss strategic needs of both the science development within IMARES and the research questions of EL&I, thus the programme now also contains a specific project request on an research subject relevant to IMARES and EL&I needs. The KBWOT Fisheries programme will fund 12 projects in 2011. The projects will investigate competition in exploited fish communities, long term changes in eel populations, the spawning habitat of mackerel, sub-stock structure in fish, trawling impact on benthic communities, quality assurance in fish aging, surveys of shellfish, maturity staging of fish and acoustic methods. Plus a targeted project specifically designed to research needs of IMARES and EL&I will be carried out into the trade-offs in FMSY targets for North Sea flatfish fisheries

The Kennisbasis WOt Fisheries Programme carried out in 2010: Final Report

The KBWOT Fisheries programme is core to the maintenance and development of the expertise that underpins the statutory obligations of fisheries monitoring and advice for the Netherlands. As the WOT obligations of the Netherlands change over time, the KBWOT programme remains flexible and responsive to developments and innovations in methods and policy needs. The core principles of the programme are maintaining expertise whilst being forward looking, ensuring value for money and strong collaboration with client ministries. The programme operates through long term projects (multiannual) and annual projects in response to scientific and societal needs. The KBWOT fisheries programme must operate within the context of the reform of the common fisheries policy (CFP), the development of the EU marine strategy framework directive (MSFD) and the EU Maritime Policy

Report of the KB-WOT fisheries programme carried out in 2009

This report documents the activities of the KB WOT fisheries programme carried out in 2009. It gives the results, products and documents the experience gained by staff through the programme

KB - WOT Fisheries Research; programme for 2010

LNV programme WOT 5 covers the execution of statutory tasks (WOT) in fisheries carried out by DLO. Part of the KB programme, presented in this report, contains resources earmarked to maintain and develop the expertise needed to carry out the WOT programme. As well as maintaining expertise, innovation is an important part of the programme. The programme is also part of the Wageningen UR Kennisbasis and comes under the theme KB01: “Groene en blauwe ruimte”. This report describes the allocation and utilisation of the Kennisbasis budget in 2010. The available budget in 2010 is €621 000. The structure of the KBWOT programme is similar to that in 2009. The money is spent through projects, each of which is described in this report. The projects are split up into four priority research areas: A) Influence of changes in the environment on marine ecosystems, B) impact of fisheries on ecosystems, C) changing fishery management, D) maintenance and international exchange of key WOT expertise. These priority research areas have been developed with the agreement of LNV. All of these areas fall under the wider WUR kennisbasis themes

KB-WOT Fisheries Research; programme for 2008

LNV programme 406 covers the execution of statutory tasks (WOT) in fisheries carried out by DLO. Part of the KB programme, presented in this report, contains resources earmarked to maintain and develop the expertise needed to carry out the WOT programme. As well as maintaining expertise, innovation is an important part of the programme. The programme is also part of the Wageningen UR Kennisbasis and comes under the theme KB01: “Groene en blauwe ruimte”. This report describes the allocation and utilisation of the Kennisbasis budget in 2008. The available budget in 2008 is €621 000. The money is spent through projects, each of which is described here. The projects are split up into 4 research priority areas: A) Influence of changes in the environment on marine ecosystems, B) impact of fisheries on ecosystems, C) changing fishery management, D) maintenance and international exchange of key WOT expertise. All of these areas fall under the wider WUR "kennisbasis" theme

Creatine kinase in energy metabolic signaling in muscle

There has been much debate on the mechanism of regulation of mitochondrial ATP synthesis to balance ATP consumption during changing cardiac workloads. A key role of creatine kinase (CK) isoenzymes in this regulation of oxidative phosphorylation and in intracellular energy transport had been proposed, but has in the mean time been disputed for many years. It was hypothesized that high-energy phosphoryl groups are obligatorily transferred via CK; this is termed the phosphocreatine shuttle. The other important role ascribed to the CK system is its ability to buffer ADP concentration in cytosol near sites of ATP hydrolysis. 

Almost all of the experiments to determine the role of CK had been done in the steady state, but recently the dynamic response of oxidative phosphorylation to quick changes in
cytosolic ATP hydrolysis has been assessed at various levels of inhibition of CK. Steady state models of CK function in energy transfer existed but were unable to explain the dynamic response with CK inhibited.

The aim of this study was to explain the mode of functioning of the CK system in heart, and in particular the role of different CK isoenzymes in the dynamic response to workload steps. For this purpose we used a mathematical model of cardiac muscle cell energy metabolism containing the kinetics of the key processes of energy production, consumption and transfer pathways. The model underscores that CK plays indeed a dual role in the cardiac cells. The buffering role of CK system is due to the activity of myofibrillar CK (MMCK) while the energy transfer role depends on the activity of mitochondrial CK (MiCK). We propose that this may lead to the differences in regulation mechanisms and energy transfer modes in species with relatively low MiCK activity such as rabbit in comparison with species with high MiCK activity such as rat.

The model needed modification to explain the new type of experimental data on the dynamic response of the mitochondria. We submit that building a Virtual Muscle Cell is not possible without continuous experimental tests to improve the model. In close interaction with experiments we are developing a model for muscle energy metabolism and transport mediated by the creatine kinase isoforms which now already can explain many different types of experiments

Exploring pathways for sustainable water management in river deltas in a changing environment

Exploring adaptation pathways into an uncertain future can support decisionmaking in achieving sustainable water management in a changing environment. Our objective is to develop and test a method to identify such pathways by including dynamics from natural variability and the interaction between the water system and society. Present planning studies on long-term water management often use a few plausible futures for one or two projection years, ignoring the dynamic aspect of adaptation through the interaction between the water system and society. Our approach is to explore pathways using multiple realisations of transient scenarios with an Integrated Assessment Meta Model (IAMM). This paper presents the first application of the method using a hypothetical case study. The case study shows how to explore and evaluate adaptation pathways. With the pathways it is possible to identify opportunities, threats, timing and sequence of policy options, which can be used by policymakers to develop water management roadmaps into the future. By including the dynamics between the water system and society, the influence of uncertainties in both systems becomes clearer. The results show, among others, that climate variability rather than climate change appears to be important for taking decisions in water management

Effect analysis of transient scenarios for successful water management strategies

Recent scenario studies on water management focus on one or two projection years and the effects on the water system and functions. The future is however more complex and dynamic. Therefore, we analyse transient scenarios in order to evaluate the performance of water management strategies. Current available simulation tools are not suitable for this purpose. Therefore, we have developed and used a tool to simulate 50-100 year long time series and that is good and fast enough to simulate the effects of these scenarios and strategies on the water system and the interaction with the human system. We present the first step by means of a case study