Relationship between serum C-reactive protein and obesity in children

Background : Obesity predisposes individuals to cardiovascular diseases.The aim of this research is to study CRP as a prognostic inflamatory factor in children with obesity and overweight in comparison with non obese ones. Materials and Methods: We investigated 80 children aged 8- 10 years assessing obesity as case group and 80 non-obese children as control group. Serum level of Cholesterol , triglycerides , low-density lipoproteins (LDL), high-density lipoproteins (HDL) and C-reactive protein were measured . Finally the data were analysed using SPSS software, X2,t and fisher tests. Results: The results showed that there were significant correlations between CRP in obese children than non-obese children. 31% of the case group had positive CRP (PV=0.000001). Lipid analysis showed significant correlations between mean Cholesterol level and CRP in obese and non-obese children. Mean Cholesterol level in posetive CRP group was 201.9 mg/dl but mean Cholesterol level in control group was 183.1 mg/dl . (P=0.04,T=-2.1) Conclusion: This study showed significant correlations between CRP and obesity in 8-10 years old children