494 research outputs found

    763-1 Assessment of Left Ventricular Function by Circumferential Stress-Midwall Shortening Relations in Dilated Cardiomyopathy

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    Echocardiographic stress endocardial shortening relations provide estimates of LV contractility that do not uniformly detect myocardial dysfunction in dilated cardiomyopathy (DCM). Recently it has become apparent that midwall (mid) fractional shortening and circumferential (c) end-systolic stress (ESS) provide the most appropriate paired afterload and function measures. Both meridional (m) and cESS were related to both endocardial (e) FS and midFS in 42 patients with DCM (98% dead during follow-up; eFS =4% in the survivor) and in 140 normals. Eight patients (19%) fell into the 95% confidence interval of the normal relation of eFS to mESS (top panel), 14% had apparently normal midFS-mESS relations but midFS was depressed in relation to cESS in 100% of patients (lower panel). Thus, (1) use of cESS-shortening relations improves the ability to identify patients with depressed LV function; (2) use of midFS or eFS are equivalent in DCM with LV dilatation and wall thinning
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