35 research outputs found

    Application of Canadian Experience for Supply Chain Strategy and Territorial Organization of Tourist Information Centres in the Regions of Russia

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    One of the countries that have a common and long-running TIC network is Canada. The experience of this large northern country in the formation of regional information visit-service systems is of interest to Russia, since the countries in their characteristics are similar in size, distances, and natural conditions based on the supply chain strategy. Consider the TIC systems in the four Atlantic Canadian provinces. Tourist Information Centres are a new branch of services and a significant component of tourism management in many countries. In Russia, tourist information centres (TIC) are organized mainly in the largest cities of the regions and at the main sites visited. The experience of countries that are close in terms of geographic conditions and advanced in relation to the tourist infrastructure is important for the Russian regions. The study of the territorial organization of the Visitor Centres in the Atlantic Canada allows us to determine some geographical patterns. They will be taken into account when developing the system of tourist information centres in the Permsky Krai, one of the internal regions of Russia, which begin to form a high-level tourist infrastructure

    Brachytherapy procedure of choice in the localized prostate cancer treatment in patients with prostate benign hyperplasia

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    The article is devoted to the brachytherapy indication estimation as a procedure of choice in the localized prostate cancer treatment in patients with prostate benign hyperplasia. The study includes 26 patients with prostate adenocarcinoma T1c-T2b, undergone TURP prior the brachytherapy. The results of the study showed that brachytherapy in combination with TURP is an effective and safety method of localized prostate cancer treatment, causing no reduction of life quality.Π‘Ρ‚Π°Ρ‚ΡŒΡ посвящСна ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΡŽ ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΈΠΉ ΠΊ Π±Ρ€Π°Ρ…ΠΈΡ‚Π΅Ρ€Π°ΠΏΠΈΠΈ, ΠΊΠ°ΠΊ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρƒ Π²Ρ‹Π±ΠΎΡ€Π° Π² Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ Π»ΠΎΠΊΠ°Π»ΠΈΠ·ΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ Ρ€Π°ΠΊΠ° простаты Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с доброкачСствСнной Π³ΠΈΠΏΠ΅Ρ€ΠΏΠ»Π°Π·ΠΈΠ΅ΠΉ ΠΏΡ€Π΅Π΄ΡΡ‚Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹. Π’ исслСдованиС Π²ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΎ 26 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Π΄ΠΈΠ°Π³Π½ΠΎΠ·ΠΎΠΌ Π°Π΄Π΅Π½ΠΎΠΊΠ°Ρ€Ρ†ΠΈΠ½ΠΎΠΌΠ° ΠΏΡ€Π΅Π΄ΡΡ‚Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ Π² стадиях Π’1с-Π’2Π¬, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹ΠΌ Π±Ρ‹Π»Π° Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½Π° Ρ‚Ρ€Π°Π½ΡΡƒΡ€Π΅Ρ‚Ρ€Π°Π»ΡŒΠ½Π°Ρ рСзСкция ΠΏΡ€Π΅Π΄ΡΡ‚Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ ΠΈ Π² ΠΏΠΎΡΠ»Π΅Π΄ΡƒΡŽΡ‰Π΅ΠΌ брахитСрапия. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½Π½ΠΎΠ³ΠΎ исслСдования ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΈ, Ρ‡Ρ‚ΠΎ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½ΠΈΠ΅ Π±Ρ€Π°Ρ…ΠΈΡ‚Π΅Ρ€Π°ΠΏΠΈΠΈ Π² ΠΊΠΎΠΌΠ±ΠΈΠ½Π°Ρ†ΠΈΠΈ с ΠΏΠ°Ρ€Ρ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠΉ Ρ‚Ρ€Π°Π½ΡΡƒΡ€Π΅Ρ‚Ρ€Π°Π»ΡŒΠ½ΠΎΠΉ Ρ€Π΅Π·Π΅ΠΊΡ†ΠΈΠ΅ΠΉ ΠΏΡ€Π΅Π΄ΡΡ‚Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ Π² Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ Π»ΠΎΠΊΠ°Π»ΠΈΠ·ΠΎΠ²Π°Π½Π½Ρ‹Ρ… Ρ„ΠΎΡ€ΠΌ Ρ€Π°ΠΊΠ° простаты являСтся эффСктивным ΠΈ бСзопасным ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ лСчСния с отсутствиСм сниТСния качСства ΠΆΠΈΠ·Π½ΠΈ

    Optimization of clinical approaches to early diagnostics of bladder cancer in Sverdlovsk region

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    The following article reveals analysis of Governor’s program β€œUrological health of man" achievements in eight cities of Sverdlovsk region. In described cities exists wide variety of different unfavorable factors, which affect on morbidity of bladder oncological diseases among man. Governor’s program positive influence on optimization of bladder cancer earlier diagnostics, based on mass questioning technique and newest medical technologies, is showed up.Π’ Ρ€Π°Π±ΠΎΡ‚Π΅ прСдставлСны Π΄Π°Π½Π½Ρ‹Π΅ ΡƒΠ³Π»ΡƒΠ±Π»Π΅Π½Π½Ρ‹Ρ… комплСксных обслСдований 114989 ΠΌΡƒΠΆΡ‡ΠΈΠ½, ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½Π½Ρ‹Ρ… Π² Π΄Π²Π΅Π½Π°Π΄Ρ†Π°Ρ‚ΠΈ экспрСсс - диагностичСских урологичСских ΠΊΠ°Π±ΠΈΠ½Π΅Ρ‚Π°Ρ… Π² БвСрдловской области ΠΈ Π² урологичСском поликлиничСском ΠΎΡ‚Π΄Π΅Π»Π΅Π½ΠΈΠΈ областной клиничСской Π±ΠΎΠ»ΡŒΠ½ΠΈΡ†Ρ‹ β„– 1. Π£ 94894 (82,5%) Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊ ΠΎΠ±Π½Π°Ρ€ΡƒΠΆΠ΅Π½Ρ‹ Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Π΅ урологичСскиС ΠΈ нСфрологичСскиС заболСвания, Π² Ρ‚ΠΎΠΌ числС Ρƒ 3533 (3,1%) ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² Π³ΠΎΡ€ΠΎΠ΄ΠΎΠ² области установлСн Ρ€Π°ΠΊ ΠΌΠΎΡ‡Π΅Π²ΠΎΠ³ΠΎ пузыря. Π”ΠΎΠΊΠ°Π·Π°Π½ΠΎ, Ρ‡Ρ‚ΠΎ организация спСциализированной Ρ€Π°Π½Π½Π΅ΠΉ диагностики Ρ€Π°ΠΊΠ° ΠΌΠΎΡ‡Π΅Π²ΠΎΠ³ΠΎ пузыря Ρƒ муТского насСлСния области ΠΏΡ€ΠΈ Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ΠΈΠΈ губСрнаторской ΠΏΡ€ΠΎΠ³Ρ€Π°ΠΌΠΌΡ‹ Π·Π° счСт доступности ΠΈ возмоТности Ρƒ ΠΌΡƒΠΆΡ‡ΠΈΠ½ ΠΏΠΎΠ»ΡƒΡ‡ΠΈΡ‚ΡŒ ΠΏΠΎ мСсту ΠΆΠΈΡ‚Π΅Π»ΡŒΡΡ‚Π²Π° ΡΠ²ΠΎΠ΅Π²Ρ€Π΅ΠΌΠ΅Π½Π½ΡƒΡŽ диагностику ΠΈ Π»Π΅Ρ‡Π΅Π½ΠΈΠ΅ онкологичСских Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ позволяСт мСдицинским Ρ€Π°Π±ΠΎΡ‚Π½ΠΈΠΊΠ°ΠΌ своСврСмСнно ΠΈ качСствСнно ΠΎΠΊΠ°Π·Ρ‹Π²Π°Ρ‚ΡŒ ΠΌΠ΅Π΄ΠΈΡ†ΠΈΠ½ΡΠΊΡƒΡŽ ΠΏΠΎΠΌΠΎΡ‰ΡŒ, диспансСрноС наблюдСниС, Ρ‚Π΅ΠΌ самым ΡΠ½ΠΈΠ·ΠΈΡ‚ΡŒ Π»Π΅Ρ‚Π°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ ΠΈ количСство ослоТнСний

    Hie factors’ influence on the choice of urine derivation after radical cystectomy

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    Following article reveals data about used methods of urine derivation after radical cystectomy in urological clinic of Ural state medical academy during yy. 2002-2008. During the shown period 135 radical cystectomy operations with different urine derivation methods were done. Choice of derivation method is complicated, multiple-factor and decided problem.Π’ Ρ€Π°Π±ΠΎΡ‚Π΅ прСдставлСны Π΄Π°Π½Π½Ρ‹Π΅ ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΡƒΠ΅ΠΌΡ‹Ρ… Π²Π°Ρ€ΠΈΠ°Π½Ρ‚ΠΎΠ² Π΄Π΅Ρ€ΠΈΠ²Π°Ρ†ΠΈΠΈ ΠΌΠΎΡ‡ΠΈ послС Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΡŒΠ½ΠΎΠΉ цистзктомии Π² условиях ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΈ ΡƒΡ€ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π“ΠžΠ£ Π’ΠŸΠž Β«Π£Π“ΠœΠΒ» Π½Π° Π±Π°Π·Π΅ Π“Π£Π— Π‘ΠžΠšΠ‘ β„– 1 с 2002 ΠΏΠΎ 2009 Π³Π³. Π—Π° ΡƒΠΊΠ°Π·Π°Π½Π½Ρ‹ΠΉ ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ΠΎ 135 Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΡŒΠ½Ρ‹Ρ… цистэктомий с Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹ΠΌΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Π°ΠΌΠΈ отвСдСния ΠΌΠΎΡ‡ΠΈ. Π’Ρ‹Π±ΠΎΡ€ ΠΌΠ΅Ρ‚ΠΎΠ΄Π° Π΄Π΅Ρ€ΠΈΠ²Π°Ρ†ΠΈΠΈ ΠΌΠΎΡ‡ΠΈ являСтся слоТной, ΠΌΠ½ΠΎΠ³ΠΎΡ„Π°ΠΊΡ‚ΠΎΡ€Π½ΠΎΠΉ ΠΈ Π΄ΠΎ ΠΊΠΎΠ½Ρ†Π° Π½Π΅ Ρ€Π΅ΡˆΡ‘Π½Π½ΠΎΠΉ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠΎΠΉ

    Minimally invasive open bladder resection

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    A new method of bladder cancer surgical treatment (minimally invasive open resection) was invented in urology department of Ural state medical academy. During yy. 2002-2007 39 patients (8 female, 31 male) were treated, following current methodic, considering indications and contraindications. Analysis of postoperative results displayed serious reduction department staying (less than 7 days) because of minimally invasive treatment, blood supply and innervation saving, ability of BCG instillations. Dispensary observation, during the period yy. 2002-2007 revealed considerable reduction of bladder cancer recurrences (15 patients - 39%) after microinvasive resection that is below between all amount of recurrences after traditional open operations.Π’ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠ΅ ΡƒΡ€ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π£Ρ€Π°Π»ΡŒΡΠΊΠΎΠΉ государствСнной мСдицинской Π°ΠΊΠ°Π΄Π΅ΠΌΠΈΠΈ (Π£Π“ΠœΠ) Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚Π°Π½ Π½ΠΎΠ²Ρ‹ΠΉ ΠΌΠ΅Ρ‚ΠΎΠ΄ ΠΎΠΏΠ΅Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΎΠ³ΠΎ лСчСния Ρ€Π°ΠΊΠ° ΠΌΠΎΡ‡Π΅Π²ΠΎΠ³ΠΎ пузыря β€” малоинвазивная открытая рСзСкция. По Π΄Π°Π½Π½ΠΎΠΉ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈΠΊΠ΅ Π·Π° ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ 2002-2007 Π³. Π±Ρ‹Π»ΠΎ ΠΏΡ€ΠΎΠΎΠΏΠ΅Ρ€ΠΈΡ€ΠΎΠ²Π°Π½ΠΎ 39 Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… (8 ΠΆΠ΅Π½Ρ‰ΠΈΠ½ ΠΈ 31 ΠΌΡƒΠΆΡ‡ΠΈΠ½Π°) с ΡƒΡ‡Π΅Ρ‚ΠΎΠΌ ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½Π½Ρ‹Ρ… ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΈΠΉ ΠΈ ΠΏΡ€ΠΎΡ‚ΠΈΠ²ΠΎΠΏΠΎΠΊΠ°Π·Π°Π½ΠΈΠΉ. Анализ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΎΠ² послСопСрационного тСчСния ΠΈ диспансСрного наблюдСния Π·Π° ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌΠΈ выявил Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ΅ сокращСниС прСбывания Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… Π² стационарС (Π½Π΅ Π±ΠΎΠ»Π΅Π΅ 7 Π΄Π½Π΅ΠΉ) Π·Π° счСт малоинвазивности ΠΏΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½Π½ΠΎΠ³ΠΎ ΠΌΠ΅Ρ‚ΠΎΠ΄Π° -сохранСния кровоснабТСния ΠΈ ΠΈΠ½Π½Π΅Ρ€Π²Π°Ρ†ΠΈΠΈ прямых ΠΌΡ‹ΡˆΡ† ΠΆΠΈΠ²ΠΎΡ‚Π°, Π° Ρ‚Π°ΠΊΠΆΠ΅ возмоТности провСдСния Π½Π° Π±ΠΎΠ»Π΅Π΅ Ρ€Π°Π½Π½ΠΈΡ… сроках (30 сутки) курса Π²Π½ΡƒΡ‚Ρ€ΠΈΠΏΡƒΠ·Ρ‹Ρ€Π½Ρ‹Ρ… инстилляций Π²Π°ΠΊΡ†ΠΈΠ½Ρ‹ Π‘Π¦Π–. ДиспансСрноС наблюдСниС Π·Π° ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌΠΈ (2002-2007 Π³Π³.) выявило: Ρ€Π΅Ρ†ΠΈΠ΄ΠΈΠ² Ρ€Π°ΠΊΠ° ΠΌΠΎΡ‡Π΅Π²ΠΎΠ³ΠΎ пузыря Π±Ρ‹Π» Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ Ρ€Π΅ΠΆΠ΅ β€” 15 Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… (39%) послС ΠΌΠ°Π»ΠΎΠΈΠ½Π²Π°Π·ΠΈΠ²Π½ΠΎΠΉ Ρ€Π΅Π·Π΅ΠΊΡ†ΠΈΠΈ, Ρ‡Ρ‚ΠΎ Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ Π½ΠΈΠΆΠ΅ ΠΎΠ±Ρ‰Π΅Π³ΠΎ количСства Ρ€Π΅Ρ†ΠΈΠ΄ΠΈΠ²ΠΎΠ², рСгистрируСмых послС Ρ‚Ρ€Π°Π΄ΠΈΡ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΎΡ‚ΠΊΡ€Ρ‹Ρ‚Ρ‹Ρ… Π²ΠΌΠ΅ΡˆΠ°Ρ‚Π΅Π»ΡŒΡΡ‚Π²

    Choice of derivation method after cystectomy

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    Following article reveals data about used methods of urine derivation after radical cystectomy in urological clinic of Ural state medical academy during yy. 2002-2008. During the shown period 117 radical cystectomy operations with different urine derivation methods were done. Choice of derivation method is complicated, multiple-factor and decided problem.Π’ Ρ€Π°Π±ΠΎΡ‚Π΅ прСдставлСны Π΄Π°Π½Π½Ρ‹Π΅ ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΡƒΠ΅ΠΌΡ‹Ρ… Π²Π°Ρ€ΠΈΠ°Π½Ρ‚ΠΎΠ² Π΄Π΅Ρ€ΠΈΠ²Π°Ρ†ΠΈΠΈ ΠΌΠΎΡ‡ΠΈ послС Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΡŒΠ½ΠΎΠΉ цистэктомии Π² условиях ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΈ ΡƒΡ€ΠΎΠ»ΠΎΠ³ΠΈΠΈ Π“ΠžΠ£ Π’ΠŸΠž Β«Π£Π“ΠœΠΒ» Π½Π° Π±Π°Π·Π΅ Π“Π£Π— Π‘ΠžΠšΠ‘ β„– 1 с 2002 ΠΏΠΎ 2008 Π³Π³. Π—Π° ΡƒΠΊΠ°Π·Π°Π½Π½Ρ‹ΠΉ ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ Π²Ρ‹ΠΏΠΎΠ»Π½Π΅Π½ΠΎ 117 Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΡŒΠ½Ρ‹Ρ… цистэктомий с Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹ΠΌΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Π°ΠΌΠΈ отвСдСния ΠΌΠΎΡ‡ΠΈ. Π’Ρ‹Π±ΠΎΡ€ ΠΌΠ΅Ρ‚ΠΎΠ΄Π° Π΄Π΅Ρ€ΠΈΠ²Π°Ρ†ΠΈΠΈ ΠΌΠΎΡ‡ΠΈ являСтся слоТной, ΠΌΠ½ΠΎΠ³ΠΎΡ„Π°ΠΊΡ‚ΠΎΡ€Π½ΠΎΠΉ ΠΈ Π΄ΠΎ ΠΊΠΎΠ½Ρ†Π° Π½Π΅ Ρ€Π΅ΡˆΠ΅Π½Π½ΠΎΠΉ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΠΎΠΉ

    Is it necessary to apply the Tyumen experience of intracoronary interventions in the Chelyabinsk region

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    Aim: to evaluate the prevalence and characteristics of percutaneous coronary interventions (PCI) performed in the Ural federal district (in particular in Tyumen and Chelyabinsk regions) in 2010 and to assess the efficiency of PCI in CAD in the real clinical practice by the data of Tyumen Cardiology Center (TCC). In the Chelyabinsk region insufficient usage of PCI was noticed (124.8 PCI in 1 million inhabitants compared to 720.4 PCI in the Tyumen region). The efficacy of PCI in patients with CAD was proven by the improvement of long-term results and patients quality of life especially if regular medical check-ups are performed. Our data show that PCI should be used more frequently in the real clinical practice in all Russian regions, and in the Chelyabinsk region as well.ЦСлью Ρ€Π°Π±ΠΎΡ‚Ρ‹ явился Π°Π½Π°Π»ΠΈΠ· частоты ΠΈ особСнностСй выполнСния чрСскоТных ΠΊΠΎΡ€ΠΎΠ½Π°Ρ€Π½Ρ‹Ρ… Π²ΠΌΠ΅ΡˆΠ°Ρ‚Π΅Π»ΡŒΡΡ‚Π² (Π§ΠšΠ’) Π² Π£Ρ€Π°Π»ΡŒΡΠΊΠΎΠΌ Ρ„Π΅Π΄Π΅Ρ€Π°Π»ΡŒΠ½ΠΎΠΌ ΠΎΠΊΡ€ΡƒΠ³Π΅, Π² частности Π² ВюмСнской ΠΈ ЧСлябинской областях Π² 2010 Π³., Π° Ρ‚Π°ΠΊΠΆΠ΅ ΠΎΡ†Π΅Π½ΠΊΠ° эффСктивности Π§ΠšΠ’ ΠΏΡ€ΠΈ Π˜Π‘Π‘ Π² Ρ€Π΅Π°Π»ΡŒΠ½ΠΎΠΉ клиничСской ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΠ΅ ΠΏΠΎ Π΄Π°Π½Π½Ρ‹ΠΌ Π€ΠΈΠ»ΠΈΠ°Π»Π° НИИ ΠΊΠ°Ρ€Π΄ΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ БО РАМН «ВюмСнский кардиологичСский Ρ†Π΅Π½Ρ‚Ρ€Β» (ВКЦ). Π’ ЧСлябинской области отмСчаСтся нСдостаточная ΠΎΠ±Π΅ΡΠΏΠ΅Ρ‡Π΅Π½Π½ΠΎΡΡ‚ΡŒ насСлСния Π§ΠšΠ’ (124,8 ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΉ Π½Π° 1 ΠΌΠ»Π½. ΠΆΠΈΡ‚Π΅Π»Π΅ΠΉ, Ρ‡Ρ‚ΠΎ Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎ уступаСт количСству Π²ΠΌΠ΅ΡˆΠ°Ρ‚Π΅Π»ΡŒΡΡ‚Π² Π² ВюмСнской области - 720,4 Π§ΠšΠ’ Π½Π° 1 ΠΌΠ»Π½. насСлСния). Π­Ρ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΉ Π§ΠšΠ’ Π² Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ Π˜Π‘Π‘, доказанная ΡƒΠ»ΡƒΡ‡ΡˆΠ΅Π½ΠΈΠ΅ΠΌ ΠΎΡ‚Π΄Π°Π»Π΅Π½Π½ΠΎΠ³ΠΎ ΠΏΡ€ΠΎΠ³Π½ΠΎΠ·Π° ΠΈ качСства ΠΆΠΈΠ·Π½ΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ², особСнно ΠΏΡ€ΠΈ Π°ΠΊΡ‚ΠΈΠ²Π½ΠΎΠΉ диспансСризации, Π΄ΠΈΠΊΡ‚ΡƒΠ΅Ρ‚ Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ ΠΈΡ… Π±ΠΎΠ»Π΅Π΅ ΡˆΠΈΡ€ΠΎΠΊΠΎΠ³ΠΎ внСдрСния Π² ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΡƒ ΠΊΠ°ΠΊ Π²ΠΎ всСх Ρ€Π΅Π³ΠΈΠΎΠ½Π°Ρ… России Π² Ρ†Π΅Π»ΠΎΠΌ, Ρ‚Π°ΠΊ ΠΈ Π² ЧСлябинской области Π² частности

    Does botulinum therapy affect the urine microbiome of patients with neurogenic bladder? Metagenomic sequencing results

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    Introduction. Reorganization of the urinary microbiome in patients with neurogenic low urinary tract dysfunction (NLUTD) plays an important role in the pathogenesis of urinary tract infections (UTIs). However, we still do not know how the different types of NULTD therapy affect the microbiome.Purpose of the study. Was to assess the influence of botulinum toxin (BoNT) injections on the urinary microbiome.Materials and methods. Urine samples were obtained from 6 persons (4 females and 2 males) with NLUTD before BoNT therapy (200 UI) and 6 weeks after. Standard urine analysis, urine culture and 16S rRNA gene sequencing were performed. a total of 144,562 quality-filtered 16S rDNA sequence reads were processed through an Illumina MiSeq platform.Results. The results of the urine culture correlated with 16S rRNA sequencing results, but the greater number of bacterial taxa were detected. Analysis of the bacterial community in urine samples revealed between 2 and 21 species-level reads per individual. All patients before BoNT demonstrated abnormal urinary microbiome with a predominance of Enterobacteriales. In three cases in females, clinical and urodynamic improvement after botulinum therapy was associated with changing of the microbiome from Enterobacteriaceae to Lactobacillales. In one female and two males, no principal changes had happened.Conclusions. This is the first report comparing in pilot study the urinary microbiome before and after BoNT injections into the bladder wall. The results are restricted by the small number of participants. However, the promising observation about the influence of botulinum toxin therapy on urinary microbiome was obtained

    X-RAY SPECTRA AND ENERGY BAND STRUCTURE OF SOME NOBLE AND TRANSITION METAL ALUMINIDES

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    On a Γ©tudiΓ© les bandes d'Γ©mission L2. 3 et KΞ² d'aluminium dans ses alliages avec des mΓ©taux nobles et quelques mΓ©taux de transition. L'apparition des maxima de l'intensitΓ© du cΓ΄tΓ© des grandes ondes dans les spectres des alliages a Γ©tΓ© liΓ©e avec des bandes Γ©lectroniques tirantes leur origine des Γ©tats d des atomes des mΓ©taux nobles et mΓ©taux de transition. On a supposΓ© que la rΓ©gion d'Γ©nergie des bandes d-semblables Γ  voisinage des atomes d'aluminium contient aussi le nombre considΓ©rable des Γ©tats tirants leur origine des Γ©tats s et p des atomes d'aluminium.The Al L2. 3- and KΞ²-emission bands from noble and several transition metal aluminides have been investigated. The appearance of the long-wave intensity peaks in the alloy spectra is associated with the energy bands originated from the d-states of noble and transition metal atoms. An assumption has been made that the energy region of the d-like bands in the vicinity of aluminium atoms contains appreciable amount of states arising from s- and p- aluminium atom states
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