Preserving academic poster content

posterPosters are an important way to share information between academia and industry. They are presented at national conferences, regional meetings, and even in university departments. There were almost 75,000 calls for poster submissions last year alone. Most posters are presented for only a few hours at a conference and may be difficult to translate into full papers. Posters are represented by abstracts submitted months before conferences. They may not accurately reflect poster content. A new method for preserving academic poster content is needed

Study of the betulin enriched birch bark extracts effects on human carcinoma cells and ear inflammation

<p>Abstract</p> <p>Background</p> <p>Pentacyclic triterpenes, mainly betulin and betulinic acid, are valuable anticancer agents found in the bark of birch tree. This study evaluates birch bark extracts for the active principles composition.</p> <p>Results</p> <p>New improved extraction methods were applied on the bark of <it>Betula pendula</it> in order to reach the maximum content in active principles. Extracts were analyzed by HPLC-MS, Raman, SERS and ¹³C NMR spectroscopy which revealed a very high yield of betulin (over 90%). Growth inhibiting effects were measured <it>in vitro</it> on four malignant human cell lines: A431 (skin epidermoid carcinoma), A2780 (ovarian carcinoma), HeLa (cervix adenocarcinoma) and MCF7 (breast adenocarcinoma), by means of MTT assay. All of the prepared bark extracts exerted a pronounced antiproliferative effect against human cancer cell lines. In vivo studies involved the anti-inflammatory effect of birch extracts on TPA-induced model of inflammation in mice.</p> <p>Conclusions</p> <p>The research revealed the efficacy of the extraction procedures as well as the antiproliferative and anti-inflammatory effects of birch extracts.</p