Nötral baş pozisyonunda karotis arter palpasyonu yardımıyla internal jugular ven kanülasyonunun başarı oranı

Amaç: İnternal jugular ven İJV kanülasyonu bazı klinik durumlarda baş nötral pozisyonda tutularak yapılmalıdır. Ancak bu pozisyonda hangi anatomik işaretleme noktasının kullanılması gerektiği açık değildir. Bu çalışmanın amacı baş nötral pozisyonda iken karotis arter KA palpasyonu kullanılarak yapılan sağ İJV kanülasyonunun başarı oranlarını araştırmaktır. Gereç ve yöntem: Bu prospektif randomize çalışma iki aşamada dizayn edildi. Birinci aşama: Birbirini takip eden 30 servikal bilgisayarlı tomografi görüntüsü çalışma öncesi sağ İJV ve KA arasındaki ilişkiyi belirlemek için incelendi. İkinci aşama: Sağ İJV kanülasyonu yapılması planlanan toplam 150 hasta çalışmaya alındı. Hastaların başı nötral pozisyonda tutuldu. Genel anestezi altında trendelenburg pozisyonu ve soluk sonu pozitif basınç uygulandı. Sağ İJV kanülasyonu 10 farklı klinisyen tarafından KA palpasyonu işaret noktası alınarak, iğneye medial yada laterale açı verilmeksizin uygulandı. Öncelikli hedefimiz iğne ile ilk üç girişimde sağ İJV ulaşabilme başarı oranlarının belirlenmesi idi. Bulgular: İğnenin toplam üç girişimde sağ İJV’ye ulaşma oranı %96,7 idi. Klinisyenler arasında başarı oranları açısından istatistiksel fark yoktu. Hastaların hiçbirinde KA delinmedi. Sonuç: Başın nötral pozisyonda tutulduğu hastalarda sağ İJV kanülasyonu için yüksek başarı oranlarından dolayı KA işaret noktası olarak etkili bir şekilde kullanılabili

Effect of alveolar recruitment maneuver on ischemia-modified albumin and oxidative stress in laparoscopic cholecystectomy

The effect of intraoperative recruitment maneuver on ischemia-modified albumin (IMA) and oxidative stress in performed laparoscopic cholecystectomy with intra-abdominal 12 mmHg pressure was investigated. Fifty patients undergoing laparoscopic cholecystectomy were included in the study by separating the two groups. Basal ventilator settings in both groups were set as tidal volume: 6-8 ml / kg, respiratory rate: 12 breaths / min, I: E = 1: 2, flow: 4 l / min. In group R, after intubation, 5 cm H2O PEEP was adjusted in addition to basal ventilator settings. Five minutes after CO2 insufflation and exsufflation, PEEP was step by step raised to 10-15-20 cm H2O, and patients were ventilated for 10 breaths. Venous blood samples were taken from the patients for three times in perioperative periods to measure IMA and oxidative stress.There was no difference between the groups in terms of demographic data, surgery and insufflation times. Significant differences in IMA,TOS,TAS and OSI levels within the group were observed but no difference was between groups. The recruitment maneuver that we used in laparoscopic cholecystectomies was found to have no effect reducing tissue ischemia and oxidative stress response in the intraoperative period. [Med-Science 2019; 8(2.000): 325-9

Assessment of depression and quality of life in intensive care unit nurses in a tertiary care hospital

Previous studies have shown that intensive care units (ICU) are among the most aggressive, tense and traumatic environments in the hospital. Intensive care units can cause physical and mental frazzle and damage in health care workers as much as they are for patients. In this study, it was aimed to evaluate depression and quality of life in ICU nurses in a tertiary care hospital. One hundred twenty ICU nurses, working more than 2 years in second and tertiary adult intensive care units, was included. The SF-36 Quality of Life Scale was used to assess the quality of life. The Beck Depression Inventory (BDI) was used to assess depression. The demographic data of the participants were also questioned through a separate form. The average age of nurses involved in the study (SS) 31.29 (5.23) and 65% female, 70% married, , 63% have children, and 31% were smokers. There was no statistically significant difference in the quality of life and depression scale scores of the participants according to age, gender, marital status, child ownership status, duration of intensive care study and smoking (p> 0.05). In conclusion, sociodemographic characteristics such as age, gender, marital status, having children, duration of intensive care study and smoking did not affect the quality of life and depression level of intensive care nurses working in a tertiary hospital. [Med-Science 2018; 7(1.000): 101-105

Anidulafungin induced reversible thrombocytopenia in a patient: A case report

Anidulafungin is a semisynthetic antifungal agent which is an echinocandin. Here, we presented elderly patient developed reversible severe thrombocytopenia due to anidulafungin. A 75-year-old man was admitted to the ICU with signs of hypovolemic shock and acute anemia. Amikacin therapy 15 mg/kg/day was started with the diagnosis of pneumonia due to the growth Acinetobacter baumannii. Amikacin therapy was discontinued in the treatment day 3 and began to colistin 2 mg/kg every 8 hours and imipenem 7 mg/kg every 6 hours. On hospital day 17, fluconazole 200mg/day was added to treatment due to candida albicans growth in blood culture and colistin-imipenem treatment was discontinued in the treatment. Candida albicans produced in control blood culture on floconazole therapy day 5 and the treatment was continued. Because of the increasing procalcitonin and CRP levels, liver enzyme elevation and fever 38.5 Co on fluconazole therapy day 6, anidulafungin therapy 200 mg was switched on fluconazole promptly. The dosage of anidulafungin was continued to 100 mg/day. Platelet counts was found to be six thousands anidulafungin therapy day 4. So treatment was terminated and liposomal amphotericin B treatment was started. Five days after the cessation of treatment with anidulafungin, platelets value was found to be over 100 thousand. Antifungal therapy was discontinued on liposomal amphotericin B therapy day 14, due not to the growth of microorganism in control blood culture. The patient who continue to be treated in intensive care, died due to multiorgan failure at 66 days. In conclusion; clinicians may consider monitoring platelets periodically, particularly in patients with hematologic disorders who use antibiotics and / or antifungal agents. [Med-Science 2018; 7(2.000): 456-8

The Analgesic Efficacy of Transverse Abdominis Plane Block versus Epidural Block after Caesarean Delivery: Which One Is Effective? TAP Block? Epidural Block?

Introduction and Objective. TAP block has gained popularity to provide postoperative analgesia after abdominal surgery but its advantage over epidural analgesia is disputed. For lower abdominal surgeries, epidural analgesia has been the gold standard and time-tested technique for providing postoperative analgesia, but contraindications for the same would warrant need for other equally good analgesic techniques. The objective of this study is to compare the analgesic efficacy of both the techniques. Materials and Methods. Eighty patients in the ASA I-II risk group, undergone an elective C-section, were randomly assigned to the study. In the TAP group, before the C-section, a single-dose spinal anaesthesia was performed by administering 3 ml of 0.5% hyperbaric bupivacaine to the patients when they were in the sitting position. After the C-section, an ultrasound-guided bilateral TAP block was performed in these patients in the recovery room for postoperative analgesia. In the single-dose EPI group, the patients received 16 cc of isobaric bupivacaine, 3 mg of morphine, and 50 mcg of fentanyl, making a total volume of 20 cc and being administered to the epidural space. Results. A higher level of patient satisfaction was observed in the EPI group (p=0.003). The amount (mg) of total analgesics received by the patients in the first 24 hours of the postoperative period was statistically significantly higher (p=0.021) in the TAP group compared to the EPI group. The visual analogue scale (VAS) scores of the EPI group were significantly lower compared to that of the TAP group (p<0.001). Conclusion. The epidural anaesthesia is still the golden standard to achieve a postcaesarean analgesia. Epidural anaesthesia is a considerably effective method in controlling the postoperative pain. We are of the opinion that epidural anaesthesia should be preferred in the first place to achieve a successful postcaesarean analgesia as it provides more effective pain control