176 research outputs found

    Regional Practice of Project Management in the Process of Primary Health Care Improvement by using Supply Chain Strategy

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    Abstract- The article reveals the practice of project approach application in the process of primary health care system improvement by using the supply chain strategy. A special place is given to the description of the project Ò€œHealth ManagementÒ€ implementation process, initiated in the Belgorod Region. They provided the characteristic of the project stages and its intermediate effects. They presented the experience of project activities by conditional blocks. The main results of the regional project are shown. Ideology and project activities are aimed at strategic goal achievement - the provision of life expectancy up to 75 years, including healthy one, among the regional population by 2020

    Exact solutions for equilibrium configurations of charged conducting liquid jets

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    A wide class of exact solutions is obtained for the problem of finding the equilibrium configurations of charged jets of a conducting liquid; these configurations correspond to the finite-amplitude azimuthal deformations of the surface of a round jet. A critical value of the linear electric charge density is determined, for which the jet surface becomes self-intersecting, and the jet splits into two. It exceeds the density value required for the excitation of the linear azimuthal instability of the round jet. Hence, there exists a range of linear charge density values, where our solutions may be stable with respect to small azimuthal perturbations.Comment: 7 pages, 5 figures, to appear in Physical Review

    Π˜ΠΠΠžΠ’ΠΠ¦Π˜ΠžΠΠΠ«Π• ΠœΠžΠ”Π•Π›Π˜ Π£ΠŸΠ ΠΠ’Π›Π•ΠΠ˜Π― Π‘Π˜Π‘Π’Π•ΠœΠžΠ™ ΠžΠšΠΠ—ΠΠΠ˜Π― ΠŸΠ•Π Π’Π˜Π§ΠΠžΠ™ ΠœΠ•Π”Π˜ΠšΠž-Π‘ΠΠΠ˜Π’ΠΠ ΠΠžΠ™ ПОМОЩИ (Ρ€Π΅Π³ΠΈΠΎΠ½Π°Π»ΡŒΠ½Ρ‹ΠΉ ΠΎΠΏΡ‹Ρ‚)

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    The article analyzes the practice of applying innovative models of primary health care system management in the frameworkΒ of the Belgorod region project Β«Health ManagementΒ». The special place is given to the evaluation of innovative models ofΒ primary health care organization on the Belgorod region’s territory. The experience of medical care for adults and childrenΒ in urban and rural areas by general practitioners (family doctors) is presented. Changes in the structure of primary careΒ physician admission in regional medical institutions are shown. The expediency of innovative modeling is confirmed by theΒ presence of organizational and medical-demographic effects.АнализируСтся ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΠ° примСнСния ΠΈΠ½Π½ΠΎΠ²Π°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ управлСния систСмой оказания ΠΏΠ΅Ρ€Π²ΠΈΡ‡Π½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΠΊΠΎ-санитарной ΠΏΠΎΠΌΠΎΡ‰ΠΈ Π² Ρ€Π°ΠΌΠΊΠ°Ρ… ΠΏΡ€ΠΎΠ΅ΠΊΡ‚Π° БСлгородской области Β«Π£ΠΏΡ€Π°Π²Π»Π΅Π½ΠΈΠ΅ Π·Π΄ΠΎΡ€ΠΎΠ²ΡŒΠ΅ΠΌΒ». ОсобоС мСсто отводится ΠΎΡ†Π΅Π½ΠΊΠ΅ ΠΈΠ½Π½ΠΎΠ²Π°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΌΠΎΠ΄Π΅Π»Π΅ΠΉ ΠΎΡ€Π³Π°Π½ΠΈΠ·Π°Ρ†ΠΈΠΈ ΠΏΠ΅Ρ€Π²ΠΈΡ‡Π½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΠΊΠΎ-санитарной ΠΏΠΎΠΌΠΎΡ‰ΠΈ Π½Π° Ρ‚Π΅Ρ€Ρ€ΠΈΡ‚ΠΎΡ€ΠΈΠΈ БСлгородской области. ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½ опыт мСдицинского обслуТивания взрослого ΠΈ дСтского насСлСния Π² городской ΠΈ сСльской мСстности Π²Ρ€Π°Ρ‡Π°ΠΌΠΈ ΠΎΠ±Ρ‰Π΅ΠΉ ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΠΈΒ (сСмСйными Π²Ρ€Π°Ρ‡Π°ΠΌΠΈ). ΠŸΠΎΠΊΠ°Π·Π°Π½Ρ‹ измСнСния структуры ΠΏΡ€ΠΈΠ΅ΠΌΠ° Π²Ρ€Π°Ρ‡ΠΎΠΌ ΠΏΠ΅Ρ€Π²ΠΈΡ‡Π½ΠΎΠ³ΠΎ Π·Π²Π΅Π½Π° Π² мСдицинских учрСТдСниях Ρ€Π΅Π³ΠΈΠΎΠ½Π°.Β Π¦Π΅Π»Π΅ΡΠΎΠΎΠ±Ρ€Π°Π·Π½ΠΎΡΡ‚ΡŒ ΠΈΠ½Π½ΠΎΠ²Π°Ρ†ΠΈΠΎΠ½Π½ΠΎΠ³ΠΎ модСлирования ΠΏΠΎΠ΄Ρ‚Π²Π΅Ρ€ΠΆΠ΄Π΅Π½Π° Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ΠΌ ΠΎΡ€Π³Π°Π½ΠΈΠ·Π°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… ΠΈ ΠΌΠ΅Π΄ΠΈΠΊΠΎ-дСмографичСских эффСктов

    ΠŸΠ°Ρ‚Π΅Π½Ρ‚Π½Ρ‹Π΅ слуТбы Π²ΡƒΠ·ΠΎΠ² β€” ΠΎΠ΄ΠΈΠ½ ΠΈΠ· ΠΊΠ»ΡŽΡ‡Π΅Π²Ρ‹Ρ… элСмСнтов Π² Ρ„ΠΎΡ€ΠΌΠΈΡ€ΠΎΠ²Π°Π½ΠΈΠΈ ΠΈ осущСствлСнии государствСнной ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠΈ подъСма российской экономики

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    The process of formation of a single government politics in the sphere of industrial property is discussed. It is pointed out that economical significance of the objects of IP is rising because of priority orientation of the Russian science and industry on making scientific, good production. The questions of effective legal protection and commerce realization of the IP objects are also touched. It is settled that support and development of the patent service in the institutions of higher education are necessary.ΠžΠ±ΡΡƒΠΆΠ΄Π°Π΅Ρ‚ΡΡ процСсс формирования Π΅Π΄ΠΈΠ½ΠΎΠΉ государствСнной ΠΏΠΎΠ»ΠΈΡ‚ΠΈΠΊΠΈ Π² области ΠΏΡ€ΠΎΠΌΡ‹ΡˆΠ»Π΅Π½Π½ΠΎΠΉ собствСнности. ΠŸΠΎΠ΄Ρ‡Π΅Ρ€ΠΊΠΈΠ²Π°Π΅Ρ‚ΡΡ Π²ΠΎΠ·Ρ€Π°ΡΡ‚Π°ΡŽΡ‰Π°Ρ экономичСская Π·Π½Π°Ρ‡ΠΈΠΌΠΎΡΡ‚ΡŒ ΠΎΠ±ΡŠΠ΅ΠΊΡ‚ΠΎΠ² ИБ Π² связи с ΠΏΡ€ΠΈΠΎΡ€ΠΈΡ‚Π΅Ρ‚Π½ΠΎΠΉ ΠΎΡ€ΠΈΠ΅Π½Ρ‚Π°Ρ†ΠΈΠ΅ΠΉ отСчСствСнной Π½Π°ΡƒΠΊΠΈ ΠΈ ΠΏΡ€ΠΎΠΌΡ‹ΡˆΠ»Π΅Π½Π½ΠΎΡΡ‚ΠΈ Π½Π° созданиС Π½Π°ΡƒΠΊΠΎΠ΅ΠΌΠΊΠΎΠΉ, конкурСнтоспособной ΠΏΡ€ΠΎΠ΄ΡƒΠΊΡ†ΠΈΠΈ. Π—Π°Ρ‚Ρ€Π°Π³ΠΈΠ²Π°ΡŽΡ‚ΡΡ вопросы эффСктивной ΠΏΡ€Π°Π²ΠΎΠ²ΠΎΠΉ ΠΎΡ…Ρ€Π°Π½Ρ‹ ΠΈ коммСрчСской Ρ€Π΅Π°Π»ΠΈΠ·Π°Ρ†ΠΈΠΈ ΠΎΠ±ΡŠΠ΅ΠΊΡ‚ΠΎΠ² ИБ. ΠžΠ±ΠΎΡΠ½ΠΎΠ²Ρ‹Π²Π°Π΅Ρ‚ΡΡ Π½Π΅ΠΎΠ±Ρ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ ΠΏΠΎΠ΄Π΄Π΅Ρ€ΠΆΠΊΠΈ ΠΈ развития ΠΏΠ°Ρ‚Π΅Π½Ρ‚Π½ΠΎΠΉ слуТбы Π² составС Π²ΡƒΠ·Π°

    Pleiotropic effects of erythropoietin. Influence of erythropoietin on processes of mesenchymal stem cells differentiation

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    The article notes that Ρ€uman recombinant erythropoietin is characterised as a factor which stimulates differentiation and proliferation of erythroid precursor cells, and as a tissue protective factor. Erythropoietin is one of the most perspective humoral agents which are involved in the preconditioning phenomeno

    АВОМНО-Π­ΠœΠ˜Π‘Π‘Π˜ΠžΠΠΠ«Π™ ΠΠΠΠ›Π˜Π— Π’Π«Π‘ΠžΠšΠžΠ§Π˜Π‘Π’ΠžΠ“Πž ΠžΠšΠ‘Π˜Π”Π Π’ΠžΠ›Π¬Π€Π ΠΠœΠ И ΠšΠ Π˜Π‘Π’ΠΠ›Π›ΠžΠ’ Π’ΠžΠ›Π¬Π€Π ΠΠœΠΠ’Π ΠšΠΠ”ΠœΠ˜Π― C Π˜ΠžΠΠžΠžΠ‘ΠœΠ•ΠΠΠ«Πœ ΠžΠ’Π”Π•Π›Π•ΠΠ˜Π•Πœ Π’ΠžΠ›Π¬Π€Π ΠΠœΠ

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    Determination of impurities in tungsten oxide (WO3) and cadmium tungstate crystals CdWO4 (CWO) was performed by atomic emission spectrometry with a two-jet arc plasma (TJP-AES) after ion exchange tungsten separation. Tungsten metal obtained under reduction of WO3 and CWO by hydrogen was dissolved in 30 % hydrogen peroxide solution and passed through a cation exchange column. Impurities adsorbed on the column were eluted by nitric acid solution and evaporated on graphite powder. Element concentrations in graphite concentrate of impurities were determined by TJP-AES. The technique developed allows the determination of Ag, Al, Ba, Bi, Ca, Co, Cr, Cu, Dy, Eu, Fe, Ga, Gd, Mg, Mn, Ni, Sm, and Ti with detection limits in the range of 0.5-500 (WO3) and 0.3-350 (CWO) ng/g.Keywords: tungsten oxide, cadmium tungstate, reduction by hydrogen, ion exchange chromatography, two-jet arc plasma, impurities, atomic emission spectrometry.(Russian)DOI:Β http://dx.doi.org/10.15826/analitika.2013.17.1.006Β N.P. Zaksas, L.N. Komissarova, P.S. Galkin, A.P. ZubarevaΒ Nikolaev Institute of Inorganic Chemistry SB RAS, Novosibirsk,Β Russian FederationΠžΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ примСсСй Π² оксидС Π²ΠΎΠ»ΡŒΡ„Ρ€Π°ΠΌΠ° (WO3) ΠΈ кристаллах Π²ΠΎΠ»ΡŒΡ„Ρ€Π°ΠΌΠ°Ρ‚Π° кадмия CdWO4 (CWO) ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Π°Ρ‚ΠΎΠΌΠ½ΠΎ-эмиссионной спСктромСтрии с двухструйной Π΄ΡƒΠ³ΠΎΠ²ΠΎΠΉ ΠΏΠ»Π°Π·ΠΌΠΎΠΉ (Π”Π”ΠŸ-АЭБ) послС ΠΈΠΎΠ½ΠΎΠΎΠ±ΠΌΠ΅Π½Π½ΠΎΠ³ΠΎ отдСлСния Π²ΠΎΠ»ΡŒΡ„Ρ€Π°ΠΌΠ°. ΠœΠ΅Ρ‚Π°Π»Π»ΠΈΡ‡Π΅ΡΠΊΠΈΠΉ Π²ΠΎΠ»ΡŒΡ„Ρ€Π°ΠΌ, ΠΏΠΎΠ»ΡƒΡ‡Π΅Π½Π½Ρ‹ΠΉ ΠΏΡ€ΠΈ восстановлСнии WO3 ΠΈ CWO Π²ΠΎΠ΄ΠΎΡ€ΠΎΠ΄ΠΎΠΌ, растворяли Π² 30 % растворС пСроксида Π²ΠΎΠ΄ΠΎΡ€ΠΎΠ΄Π° ΠΈ пропускали Ρ‡Π΅Ρ€Π΅Π· ΠΊΠ°Ρ‚ΠΈΠΎΠ½ΠΎΠΎΠ±ΠΌΠ΅Π½Π½ΡƒΡŽ ΠΊΠΎΠ»ΠΎΠ½ΠΊΡƒ. ΠŸΡ€ΠΈΠΌΠ΅ΡΠΈ, адсорбированныС Π½Π° ΠΊΠΎΠ»ΠΎΠ½ΠΊΠ΅, ΡΠ»ΡŽΠΈΡ€ΠΎΠ²Π°Π»ΠΈ раствором Π°Π·ΠΎΡ‚Π½ΠΎΠΉ кислоты ΠΈ ΡƒΠΏΠ°Ρ€ΠΈΠ²Π°Π»ΠΈ Π½Π° Π³Ρ€Π°Ρ„ΠΈΡ‚ΠΎΠ²Ρ‹ΠΉ ΠΏΠΎΡ€ΠΎΡˆΠΎΠΊ. Π‘ΠΎΠ΄Π΅Ρ€ΠΆΠ°Π½ΠΈΠ΅ элСмСнтов Π² Π³Ρ€Π°Ρ„ΠΈΡ‚ΠΎΠ²ΠΎΠΌ ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€Π°Ρ‚Π΅ микропримСсСй опрСдСляли ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΠΌ Π”Π”ΠŸ-АЭБ. Разработанная ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈΠΊΠ° позволяСт ΠΎΠΏΡ€Π΅Π΄Π΅Π»ΡΡ‚ΡŒ Ag, Al, Ba, Bi, Ca, Co, Cr, Cu, Dy, Eu, Fe, Ga, Gd, Mg, Mn, Ni, Sm ΠΈ Ti с ΠΏΡ€Π΅Π΄Π΅Π»Π°ΠΌΠΈ обнаруТСния 0.5-500 (WO3) ΠΈ 0.3-350 (CWO) Π½Π³/Π³.ΠšΠ»ΡŽΡ‡Π΅Π²Ρ‹Π΅ слова: оксид Π²ΠΎΠ»ΡŒΡ„Ρ€Π°ΠΌΠ°, Π²ΠΎΠ»ΡŒΡ„Ρ€Π°ΠΌΠ°Ρ‚ кадмия, восстановлСниС Π²ΠΎΠ΄ΠΎΡ€ΠΎΠ΄ΠΎΠΌ, ионообмСнная хроматография, двухструйная дуговая ΠΏΠ»Π°Π·ΠΌΠ°, примСси, Π°Ρ‚ΠΎΠΌΠ½ΠΎ-эмиссионный Π°Π½Π°Π»ΠΈΠ·.DOI:Β http://dx.doi.org/10.15826/analitika.2013.17.1.00

    Pathogenetics and underlying mechanisms, clinical evidence and treatment concepts of neurological disorders in multiple injuries of the locomotorium

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    Objective: Π’ΠΎ study the pathogenic underlying mechanisms, clinical features and correction methods of neurological disorders in cases of multiple injuries of the locomotor system at different periods of traumatic disease. Materials and methods. We have studied 109 locomotor patients with multiple injuries. We have evaluated several determined parameters of lipid metabolism, blood toxicity, central and peripheral hemodynamics, as well as the severity of autonomic dysfunction.Results. Cerebral hypoxia was commonly caused by impaired circulation and fat embolism. Autonomic disorders included cataplexy and peripheral segmental disorder. Encephalopathy syndrome was characterized by the progression of psychopathological and organic changes.ЦСль: ΠΈΠ·ΡƒΡ‡ΠΈΡ‚ΡŒ патогСнСтичСскиС ΠΌΠ΅Ρ…Π°Π½ΠΈΠ·ΠΌΡ‹, клиничСскиС особСнности ΠΈ ΠΏΡ€ΠΈΠ½Ρ†ΠΈΠΏΡ‹ ΠΊΠΎΡ€Ρ€Π΅ΠΊΡ†ΠΈΠΈ нСврологичСских Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΠΉ ΠΏΡ€ΠΈ мноТСствСнных поврСТдСниях ΠΎΠΏΠΎΡ€Π½ΠΎ-Π΄Π²ΠΈΠ³Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ систСмы Π² Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Π΅ ΠΏΠ΅Ρ€ΠΈΠΎΠ΄Ρ‹ травматичСской Π±ΠΎΠ»Π΅Π·Π½ΠΈ. ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. Π˜Π·ΡƒΡ‡Π΅Π½ΠΎ 109 ΠΏΠΎΡΡ‚Ρ€Π°Π΄Π°Π²ΡˆΠΈΡ… с мноТСствСнными Ρ‚Ρ€Π°Π²ΠΌΠ°ΠΌΠΈ ΠΎΠΏΠΎΡ€Π½ΠΎ-Π΄Π²ΠΈΠ³Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ систСмы. ИсслСдовали Π½Π΅ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ Π»ΠΈΠΏΠΈΠ΄Π½ΠΎΠ³ΠΎ ΠΎΠ±ΠΌΠ΅Π½Π°, Ρ‚ΠΎΠΊΡΠΈΡ‡Π½ΠΎΡΡ‚ΡŒ ΠΊΡ€ΠΎΠ²ΠΈ, Ρ†Π΅Π½Ρ‚Ρ€Π°Π»ΡŒΠ½ΡƒΡŽ ΠΈ ΠΏΠ΅Ρ€ΠΈΡ„Π΅Ρ€ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ Π³Π΅ΠΌΠΎΠ΄ΠΈΠ½Π°ΠΌΠΈΠΊΡƒ, Π²Ρ‹Ρ€Π°ΠΆΠ΅Π½Π½ΠΎΡΡ‚ΡŒ Π²Π΅Π³Π΅Ρ‚Π°Ρ‚ΠΈΠ²Π½ΠΎΠΉ дисфункции. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. ΠŸΡ€Π΅Π΄ΡΡ‚Π°Π²Π»Π΅Π½Ρ‹ ΠΏΡ€ΠΈΡ‡ΠΈΠ½Ρ‹ возникновСния, ΠΊΠ»ΠΈΠ½ΠΈΠΊΠ°, Π΄ΠΈΠ½Π°ΠΌΠΈΠΊΠ° ΠΈ ΠΏΡ€ΠΈΠ½Ρ†ΠΈΠΏΡ‹ лСчСния нСврологичСских Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΠΉ ΠΏΡ€ΠΈ мноТСствСнных Ρ‚Ρ€Π°Π²ΠΌΠ°Ρ… ΠΎΠΏΠΎΡ€Π½ΠΎ-Π΄Π²ΠΈΠ³Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ систСмы Π² Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Π΅ ΠΏΠ΅Ρ€ΠΈΠΎΠ΄Ρ‹ травматичСской Π±ΠΎΠ»Π΅Π·Π½ΠΈ. ΠžΡΠΎΠ±Π΅Π½Π½ΠΎΡΡ‚ΠΈ Ρ†Π΅Ρ€Π΅Π±Ρ€Π°Π»ΡŒΠ½ΠΎΠΉ гипоксии обусловлСны Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΠ΅ΠΌ циркуляции ΠΈ ΠΆΠΈΡ€ΠΎΠ²ΠΎΠΉ эмболиСй. Π’Π΅Π³Π΅Ρ‚Π°Ρ‚ΠΈΠ²Π½Ρ‹Π΅ Π½Π°Ρ€ΡƒΡˆΠ΅Π½ΠΈΡ прСдставлСны ΠΏΠ°Ρ€ΠΎΠΊΡΠΈΠ·ΠΌΠ°Π»ΡŒΠ½Ρ‹ΠΌ Π²Π°Ρ€ΠΈΠ°Π½Ρ‚ΠΎΠΌ дистонии ΠΈ пСрифСричСскими сСгмСнтарными расстройствами. ЭнцСфалопатичСский синдром характСризовался прогрСссированиСм психопатологичСских ΠΈ органичСских ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ

    Eclipsing variable stars in the Moscow program for scanning the astronomical plate stacks

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    Π Π°ΡΡΠΌΠ°Ρ‚Ρ€ΠΈΠ²Π°ΡŽΡ‚ΡΡ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹ полуавтоматичСского поиска Π·Π°Ρ‚ΠΌΠ΅Π½Π½Ρ‹Ρ… ΠΏΠ΅Ρ€Π΅ΠΌΠ΅Π½Π½Ρ‹Ρ… Π·Π²Π΅Π·Π΄ ΠΏΠΎ сканам московской ΠΊΠΎΠ»Π»Π΅ΠΊΡ†ΠΈΠΈ астронСгативов ΠΈ особСнности распрСдСлСния ΠΎΠ±Π½Π°Ρ€ΡƒΠΆΠ΅Π½Π½Ρ‹Ρ… Π·Π°Ρ‚ΠΌΠ΅Π½Π½Ρ‹Ρ… ΠΏΠ΅Ρ€Π΅ΠΌΠ΅Π½Π½Ρ‹Ρ… ΠΏΠΎ ΠΏΠ΅Ρ€ΠΈΠΎΠ΄Π°ΠΌ.We consider the results of our semi-automated search for eclipsing variables using scans of the Moscow astronomical plate stacks and characteristics of the eclipsing variables’ distribution over periods
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