16 research outputs found
Feline exocrine pancreatic insufficiency : a retrospective study of 150 cases
BACKGROUND : Little information is available about the clinical presentation and response to treatment of cats with exocrine
pancreatic insufficiency (EPI).
OBJECTIVES : To describe the signalment, clinical signs, concurrent diseases, and response to treatment of cats with EPI.
ANIMALS : One hundred and fifty cats with EPI.
METHODS : Retrospective case series.
RESULTS : Questionnaires were sent to 261 veterinarians, and 150 (57%) were returned with data suitable for statistical
analysis. The median age of the cats with EPI was 7.7 years. The median body condition score was 3 of 9. Ninety-two of
119 cats (77%) had hypocobalaminemia, and 56 of 119 cats (47%) had increased and 6 of 119 cats (5%) had decreased
serum folate concentrations. Clinical signs included weight loss (91%), unformed feces (62%), poor hair coat (50%), anorexia
(45%), increased appetite (42%), lethargy (40%), watery diarrhea (28%), and vomiting (19%). Eighty-seven cats
(58%) had concurrent diseases. Treatment response was reported to be good in 60%, partial in 27%, and poor in 13% of
121 cats. Trypsin-like immunoreactivity <4 lg/L was associated with a positive response to treatment (OR, 3.2; 95% CI,
1.5–7.0; P = .004). Also, cobalamin supplementation improved the response to treatment (OR, 3.0; 95% CI, 1.4–6.6;
P = .006).
CONCLUSIONS AND CLINICAL IMPORTANCE : Exocrine pancreatic insufficiency in cats often has a different clinical presentation
than in dogs. The age range for EPI in cats is wide, and many cats can be ≤5 years of age. Most cats respond well to appropriate
treatment for EPI, and cobalamin supplementation appears to be necessary for a good response.Some of the results of this study were presented at the 2012
American College of Veterinary Internal Medicine Forum, New
Orleans, LA.http://www.sherpa.ac.uk/romeo/issn/0891-6640/am2017Production Animal Studie
Cirurgia laparoscópica no diagnóstico de gastrite crônica atrófica seguida de tratamento clÃnico em cadela: relato de caso
Efeitos hemodinâmicos da anestesia em plano profundo com infusão intravenosa contÃnua de propofol ou propofol associado à lidocaÃna em cães
Dominance of Nosema ceranae in honey bees in the Balkan countries in the absence of symptoms of colony collapse disorder
Comparative disposition of pharmacologic markers for cytochrome P-450 mediated metabolism, glomerular filtration rate, and extracellular and total body fluid volume of Greyhound and Beagle dogs
Designing Studies and Rodent Models for Studying Prebiotics for Colorectal Cancer Prevention
Evaluation and optimisation of a targetcontrolled infusion system for administering propofol to dogs as part of a total intravenous anaesthetic technique during dental surgery
The performance of a modified target-controlled infusion system was investigated in 16 dogs undergoing routine dental work, by comparing the predicted concentrations of propofol in venous blood samples with direct measurements; the optimum targets for the induction and maintenance of anaesthesia were also identified. The performance of a target-controlled infusion system is considered clinically acceptable when the median prediction error, a measure of bias, is not greater than +/-10 to 20 per cent, and the median absolute performance error, a measure of the accuracy, is not greater than 20 to 30 per cent. The results fell within these limits indicating that the system performed adequately. The optimal induction target was 3 microg/ml, and anaesthesia of adequate depth and satisfactory quality was achieved with maintenance targets of between 2.5 and 4.7 microg/ml propofol. The system was easy to use and the quality of anaesthesia was adequate for dental work