Original paper Presence of selected metabolic syndrome components in patients with psoriasis vulgaris

A b s t r a c t Introduction: Recent studies have suggested a strong association between psoriasis and obesity, dyslipidemia, hypertension, resistance to insulin and metabolic syndrome. Aim: To assess the prevalence of selected metabolic syndrome components in patients with psoriasis and the effect of the abnormalities on the disease activity. Material and methods: Two hundred and forty-six patients diagnosed with psoriasis and 75 healthy individuals as controls were included in the study. Psoriasis activity was evaluated by the Psoriasis Area and Severity Index (PASI). Results: There was a statistically significant difference in triglyceride concentration between psoriasis patients and controls (p = 0.00001), which was not found for high-density lipoprotein (HDL) concentration. Mean values of serum glucose level in patients with psoriasis were significantly higher than in controls (p = 0.046). Further statistical analysis of the obtained results showed significantly higher systolic blood pressure in the psoriasis patients than in the controls (p = 0.0001), but there was no statistically significant difference in diastolic blood pressure between the investigated groups (p > 0.05). Conclusions: Higher prevalence of metabolic syndrome components was observed in patients with psoriasis than in the general population

Presence of selected metabolic syndrome components in patients with psoriasis vulgaris

Introduction: Recent studies have suggested a strong association between psoriasis and obesity, dyslipidemia, hypertension, resistance to insulin and metabolic syndrome. Aim : To assess the prevalence of selected metabolic syndrome components in patients with psoriasis and the effect of the abnormalities on the disease activity. Material and methods: Two hundred and forty-six patients diagnosed with psoriasis and 75 healthy individuals as controls were included in the study. Psoriasis activity was evaluated by the Psoriasis Area and Severity Index (PASI). Results : There was a statistically significant difference in triglyceride concentration between psoriasis patients and controls (p = 0.00001), which was not found for high-density lipoprotein (HDL) concentration. Mean values of serum glucose level in patients with psoriasis were significantly higher than in controls (p = 0.046). Further statistical analysis of the obtained results showed significantly higher systolic blood pressure in the psoriasis patients than in the controls (p = 0.0001), but there was no statistically significant difference in diastolic blood pressure between the investigated groups (p > 0.05). Conclusions : Higher prevalence of metabolic syndrome components was observed in patients with psoriasis than in the general population

Rowell’s syndrome – case report and review of the literature

Introduction. Rowell’s syndrome is a rare subtype of subacute lupus erythematosus associated with erythema multiforme-like skin lesions, positive antinuclear antibodies and anti-Ro/La-antibodies. Objective . To present a case of Rowell’s syndrome. Case report . We describe a case of an 82-year-old man who presented with erythema multiforme-like eruption on the upper extremities and trunk and fulfilled the diagnostic criteria of Rowell,s syndrome. Conclusions . Patients with these characteristic clinical and immunological features of Rowell,s syndrome are rarely seen and reported in the literature. The discussion concerning the character of the disease is still ongoing