Coopetition spectrum trading in cognitive radio networks

Spectrum trading is a promising method to improve spectrum usage efficiency. Several issues must be addressed, however, to enable spectrum trading that goes beyond conservative trading idle bands and achieve cooperation between primary and secondary users. In this paper, we argue that spectrum holes should be explicitly endogenous and negotiated by spectrum trading participants. To this end, we proposed an a Vickery auction based, coopetive framework to foster cooperation, while allowing competition for spectrum sharing. Incentive schemes and penalty for revocable spectrum are proposed to increase the spectrum access opportunities for SUs while protecting PUs spectrum value. A simultation study shows that the proposed framework outperforms conservative trading approaches, in a variety of scenarios with different levels of cooperation and bidding strategies. © 2013 IEEE

Coopetive spectrum trading - Creating endogenous spectrum holes

Dynamic spectrum access has been proposed to address the spectrum scarcity. Based on this access mode, secondary users are allowed to opportunistically operate when primary users are absent. Secondary Users are, however, required to relinquish the spectrum upon return of the incumbent spectrum holder. Although it improves spectrum utility, opportunistic spectrum access limits secondary users' access to exogenous spectrum holes vacated by primary users. We argue that spectrum holes should be endogenous, enabled by incentives to incumbent users to increase spectrum availability, while mitigating risk. To this end, we take a different perspective on dynamic spectrum sharing and propose a coopetive framework, whereby primary and secondary users engage in a cooperative, yet competitive, auction-driven spectrum sharing to enhance spectrum usage. In this framework, the primary users'spectrum is organized in three bands, namely exclusive usage, usage right and management right bands. Based on this structure, spectrum is traded as financial options to increase trading flexibility and capture the value primary and secondary users attach to spectrum access and usage. Spectrum trading between primary and secondary users is formalized as a utility maximization problem. Approximate solutions to this problem are derived and their performance is analyzed. The results show that spectrum trading, which combines revocable and exclusive leasing, provides higher utilities for both primary and secondary users. © 2014 Springer Science+Business Media New York

Coopetition spectrum trading - Creating endogenous spectrum holes

Dynamic spectrum access is an important way to alleviate the spectrum scarcity. Traditionally, secondary users are allowed to opportunistically operate when primary users are absent and buy idle bands from primary users. Although it improves the spectrum utility to some extents, it is not enough. In this paper, we argue that spectrum hole should be endogenous which means they should be negotiated by primary and secondary users. We proposed a novel spectrum sharing scheme with spectrum usage and management right. Further, we suggest spectrum trading as a financial option to capture the realistic usage and increase the trading flexibility. We show the superior of our model for primary users in deterministic and dynamic leasing environments. © 2013 ICST - The Institute for Computer Sciences, Social Informatics and Telecommunications Engineering

Clinicopathological, therapeutic and prognostic features of the triple-negative tumors in moroccan breast cancer patients (experience of Hassan II university hospital in Fez)

<p>Abstract</p> <p>Introduction</p> <p>Triple-negative breast cancer (TNBC) is defined as a group of breast carcinomas that are negative for expression of hormone receptors (ER, PR) and Her2, we can distinguish between two groups: basal-like (ER-, PR-, Her2-, cytokeratin (CK) 5/6+ and/or Her1+) and unclassified subtype (ER-, PR-, Her2-, Her1- and CK5/6-).</p> <p>The aim of this study is to determine the clinicopathological, histological, therapeutic and prognostic features associated with this type of breast cancer.</p> <p>Methods</p> <p>This is a retrospective study of 366 female breast cancer patients, diagnosed between January 2007 and June 2010 at the Department of Pathology. Epidemiological, clinical, histological, therapeutic and evolutive data were analyzed. OS and DFS rates were estimated by Kaplan-Meier analysis and a log-rank test to estimate outcome.</p> <p>Results</p> <p>A total of 64 women were identified as having TNBC (17.5% of all female breast cancer patients), 12.6% were basal-like, 4.9% were unclassified subtype, with a median age of 45 years. The median histological tumor diameter was 4.3 cm. TNBC were most often associated with a high grade, 49.2% grade III (53% for unclassified subtype, 47.6% for basal-like). Vascular invasion was found in 26.6% of cases (22% for unclassified subtype and 28.3% for basal-like). For the lymph node involvement: 51% had positive lymph nodes, and 22.4% had distant metastases. Neoadjuvant chemotherapy was administered to 18% patients with 26% of complete pathologic response; therefore adjuvant chemotherapy was given to 82%. 98% received anthracycline based regimen and only 30% received taxanes.</p> <p>The Kaplan-Meier curves based showed the lowest survival probability at 3-years (49% of OS, and 39% of DFS).</p> <p>Conclusion</p> <p>TNBC is associated with young age, high grade tumors, advanced stage at diagnosis, difference chemo response compared to other subtypes, and shortest survival. Critical to optimal future management is accurate identification of truly triple negative disease, and adequately powered prospective TNBC trials to establish treatment efficacy and define predictive biomarkers.</p