Political management of youth students’ electoral participation in Russia: topical issues

Electoral participation is the most accessible way for citizens to influence the political course of the country. This determines the relevance of the chosen research topic. In the course of the study, the authors found that a set of measures, aimed at changing the order of organization and conduct of voting in Russia, contributed to an increase in the effectiveness of the electoral process and the interest of the youth audience in political activity. The purpose of this study is to identify modern mechanisms of political management of electoral participation of student youth in Russia. The objectives of this study are to study the interest of student youth in the implementation of socio-political activities, as well as to identify the features of electoral behavior of student youth in Russia. The research was conducted using such methods as: classical analysis of documents, the method of comparative analysis and the survey conducted in the form of a questionnaire using the Google.forms resource. The results of the author’s sociological research “Political activity of youth as a factor of electoral participation in Russia” show that students are willingly interested in socio-political activities and express their interest in the development of civic initiative. In the course of the study we found a growing interest among students in a new, for Russia, form of political participation – political volunteering

Характерные особенности спектров HLA-аллелей классов I и II у пациентов с различными клиническими формами ювенильного идиопатического артрита в Республике Беларусь

The genes of the major histocompatibility complex (HLA) play a significant role in the genetic predisposition to juvenile idiopathic arthritis (JIA) and determine up to 18 % of disease risk. This work was aimed to reveal associations of the HLA characteristic pattern with two clinically different forms of JIA in the Belarusian population. 24 patients diagnosed with systemic JIA, 24 patients with oligoarticular JIA and 24 healthy controls were included into the study. High-throughput HLA typing for 11 loci was performed using TruSight HLA v2 Sequencing Panel (Illumina) on the MiSeq system. DQB1*04:02:01 (p = 0.026; OR 5.88 [1.20–28.72]), DRB1*08:01:01 (p = 0.07; OR 3.94 [1.01–15.39]) and DR8-haplotype (p = 0.006; OR 3.95 [1.34–11.63]) frequencies were significantly higher in patients with oligoarthritis but not systemic JIA when compared with controls. While DQA1*05:01:01 and DQB1*02:01:01 alleles showed a protective effect against both systemic (p = 0.007, OR 0.08 [0.009–0.65]; p = 0.01, OR 0.09 [0.01–0.83]) and oliarticular JIA (p = 0.026, OR 0.16 [0.03–0.79]; p = 0.046, OR 0.2 [0.04–1.00], the negative association of the DRB1*03:01 allele was revealed only for systemic JIA (p = 0.03, OR 0.11 [0.01–0.88]). Thus, the obtained results suggest that different HLA-patterns are involved into the formation of various JIA subtypes.Гены главного комплекса гистосовместимости HLA играют существенную роль в генетической предрасположенности к ювенильному идиопатическому артриту (ЮИА) и определяют до 18 % риска развития заболевания. Учитывая гипервариабельность генов HLA и специфичность их аллельных спектров в зависимости от популяции, представляло интерес провести HLA-типирование пациентов с ЮИА, проживающих на территории Республики Беларусь, для установления аллелей, ассоциированных с отдельными клиническими формами заболевания. В работе с помощью высопроизводительного секвенирования нового поколения (Illumina) для 48 детей с системным и олигоартикулярным подтипами ЮИА и контрольной группы (n = 24) был определен спектр HLA-аллелей по 11 локусам (HLA-A, B, C, DPA1, DPB1, DQA1, DQB1, DRB1/3/4/5). Установлено, что аллели HLA-DQB1*04:02:01 (OR 5,88 [1,20–28,72], p = 0,026), HLA-DRB1*08:01:01 (OR 3,94 [1,01–15,39], p = 0,07) и гаплотип DR8 (OR 3,95 [1,34–11,63], p = 0,006) ассоциированы с риском возникновения олигоартикулярного ЮИА. Выявлены аллели, снижающие риск развития системной формы заболевания (HLA-DRB1*03:01, OR 0,11 [0,01–0,88], p = 0,03), либо оказывающие протективный эффект по отношению к обеим рассматриваемым формам ЮИА (DQA1*05:01:01 (OR 0,08 [0,009–0,65], p = 0,007 и OR 0,16 [0,03–0,79], p = 0,026) и DQB1*02:01:01 OR 0,09 [0,01–0,83], p = 0,01 и OR 0,20 [0,04–1,00], p = 0,046 для системного и олигоартикулярного ЮИА соответственно). Таким образом, полученные результаты позволяют предположить, что в формировании различных клинических форм ЮИА задействованы различные HLA-паттерны

Результаты современных радиационно-гигиенических обследований приграничных с Республикой Беларусь населенных пунктов Брянской области Российской Федерации. Часть 1: Характеристика населенных пунктов

This study presents results of radiation-hygienic surveys of the Bryansk Oblast settlements bordering the Republic of Belarus. The data were obtained in the course of implementation of measures of the “Program of joint activities of Russia and Belarus within the framework of the Union State for the protection of the population and rehabilitation of the territories affected by the Chernobyl NPP accident” in 2019–2022. The first part of the study presents a general characteristic of the current state of the problem of returning the residents of radioactively contaminated territories to normal living conditions and provides information on the settlements of the surveyed region. The modern demographic composition of the population is considered; the structure of private subsidiary plots is investigated. The results described in this part of the study indicate the main ways, which are relevant for the formation of the internal exposure dose of the public at the current stage of the radiation accident.В статье приводятся результаты радиационно-гигиенических обследований приграничных с Республикой Беларусь населенных пунктов Брянской области, полученные в 2019–2022 гг. в ходе реализации мероприятий «Программы совместной деятельности России и Беларуси в рамках Союзного государства по защите населения и реабилитации территорий, пострадавших в результате катастрофы на Чернобыльской АЭС». В первой части статьи дана общая характеристика современного состояния проблемы возвращения жителей радиоактивно загрязненных территорий к условиям нормальной жизнедеятельности и приводятся сведения о населенных пунктах обследованного региона. Рассмотрен современный демографический состав населения, исследована структура личных подсобных хозяйств. На основании результатов, описанных в данной части публикации, выделены основные пути формирования дозы внутреннего облучения населения, актуальные для современного этапа радиационной аварии

COMPOSITION OF LYMPHOCYTE SUBSETS IN THE PATIENTS WITH SEVERE FORMS OF HERPETIC INFECTION

Evaluation of lymphocyte subsets in severe forms of herpetic infection is a necessary diagnostic test. However, interpretation of appropriate data is difficult, due to slight or multidirectional changes of immunological parameters in the patients. In present study, the indices of immune status were assessed in the patients with severe recurrent forms of chronic herpetic infection, being in remission period by the time of study. A detailed personalized analysis of immunological testing data is presented, with respect to the disease duration, recurrence frequency, and other clinical features of severe herpes infection. Various types of correlations between the lymphocyte subpopulations are described for the patients with severe recurrent herpetic infection

How do mental health first aid ™ interventions influence patient help-seeking behaviours? A dilemma for pharmacist mental health first aid responders

© 2018 Elsevier Inc. In any given year approximately 34% of the 130 million adults in the United States suffer from a mental health condition or disorder. Anxiety and depressive disorders are the most common followed by substance use disorder. Many people who suffer from a mental illness do not seek help. Studies have shown that the stigma of being perceived as having a mental illness prevents many adults from seeking help. Mental Health First Aid ™ (MHFA) is an educational program geared towards educating MHFA responders to assist those who may be experiencing a mental health condition or disorder. Pharmacists are the most accessible healthcare professionals, and many are trained in delivering MHFA. The literature on MHFA suggests that it is an effective educational program for those that take the training course. What is lacking is evidence that MHFA interventions positively affect help-seeking behaviours after an intervention has occurred between a mental health first air responder and an individual requiring MHFA. This paper highlights this issue and provides suggestions for future research

Четвертое заседание Общественного комитета содействия развитию библиотек России: «Правовая основа деятельности муниципальных библиотек: реалии и проблемы». 27 января 2009 г.

Problems of municipal libraries in the context of legal reforming were discussed at the 4th Meeting of the Public Committee for Promotion of Russian Libraries Development.На четвертом заседании Общественного комитета содействия развитию библиотек России обсуждались проблемы муниципальных библиотек в контексте проведения правовых реформ