822 research outputs found

    ASSESSMENT OF JOURNALS USED BY AGRICULTURAL ECONOMISTS AT LAND-GRANT UNIVERSITIES

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    Agricultural economists at land-grant universities were surveyed to evaluate the use and assessment of professional journals. Faculty rankings of journals are reported along with faculty perceptions of changes in the quality of selected journals. Of 25 journals used by agricultural economics faculties, the Southern Journal of Agricultural Economics ranked first among regional agricultural economics journals in personal usefulness, subscriptions held, papers submitted, papers published, and participation in the editorial and review processes. The SJAE was also ranked as the second most improved journal among all journals evaluated.Teaching/Communication/Extension/Profession,

    The enclosure method for the heat equation

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    This paper shows how the enclosure method which was originally introduced for elliptic equations can be applied to inverse initial boundary value problems for parabolic equations. For the purpose a prototype of inverse initial boundary value problems whose governing equation is the heat equation is considered. An explicit method to extract an approximation of the value of the support function at a given direction of unknown discontinuity embedded in a heat conductive body from the temperature for a suitable heat flux on the lateral boundary for a fixed observation time is given.Comment: 12pages. This is the final versio

    Screening for Diabetes and Pre-Diabetes With Proposed A1C-Based Diagnostic Criteria

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    OBJECTIVE — An International Expert Committee (IEC) and the American Diabetes Asso-ciation (ADA) proposed diagnostic criteria for diabetes and pre-diabetes based on A1C levels. We hypothesized that screening for diabetes and pre-diabetes with A1C measurements would differ from using oral glucose tolerance tests (OGTT). RESEARCH DESIGN AND METHODS — We compared pre-diabetes, dysglycemia (diabetes or pre-diabetes), and diabetes identified by the proposed criteria (A1C 6.5 % for diabetes and 6.0–6.4 % [IEC] or 5.7–6.4 % [ADA] for high risk/pre-diabetes) with standard OGTT diagnoses in three datasets. Non-Hispanic white or black adults without known diabetes who had A1C and 75-g OGTT measurements were included from the prospective Screening for Impaired Glucose Tolerance study (n 1,581), and from the National Health and Nutrition Examination Survey (NHANES) III (n 2014), and NHANES 2005–2006 (n 1,111). RESULTS — OGTTs revealed pre-diabetes in 35.8 % and diabetes in 5.2 % of combined study subjects. A1C provided receiver operating characteristic (ROC) curve areas for diabetes of 0.79– 0.83, but ROC curve areas were 0.70 for dysglycemia or pre-diabetes. The proposed criteria missed 70 % of individuals with diabetes, 71–84 % with dysglycemia, and 82–94 % with pre

    Vascular white matter lesions negatively correlate with brain metastases in malignant melanoma - results from a retrospective comparative analysis

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    Brain metastasis (BM) is a major complication of different cancers. There is increasing evidence for influence of vascular factors on BM in patients with non-small cell lung cancer (NSCLC). It is not known if the same is true for other tumors that might rely on different forms of vasculogenesis. The objective of this retrospective study was to evaluate a possible negative association of vascular white matter lesions and vascular risk factors (vasRF) with brain metastases in patients with melanoma

    On an exponential attractor for a class of PDEs with degenerate diffusion and chemotaxis

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    In this article we deal with a class of strongly coupled parabolic systems that encompasses two different effects: degenerate diffusion and chemotaxis. Such classes of equations arise in the mesoscale level modeling of biomass spreading mechanisms via chemotaxis. We show the existence of an exponential attractor and, hence, of a finite-dimensional global attractor under certain 'balance conditions' on the order of the degeneracy and the growth of the chemotactic function

    Portable instrument for in-vivo infrared oxymetry using spread-spectrum modulation

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    Near Infrared Spectroscopy (NIRS) can be employed to monitor noninvasively and continuously local changes in hemodynamics and oxygenation of human tissues. A portable NIRS research-grade acquisition system, dedicated to measurements during muscular exercise, is presented. The instrument is able to control up to eight LED sources and two detectors. A digital correlation technique, implemented on a single-chip RISC microcontroller, performs source-to-detector multiplexing. Such algorithm is highly optimized for computational efficiency and ambient noise rejection. Software-configurable input stages allow for flexibility in instrument setup. As a result of the specific correlation technique employed, the instrument is compact, lightweight and efficient. Clinical tests on oxygen consumption show excellent performance

    Portable instrument for in-vivo infrared oxymetry using spread-spectrum modulation

    Get PDF
    Near Infrared Spectroscopy (NIRS) can be employed to monitor noninvasively and continuously local changes in hemodynamics and oxygenation of human tissues. A portable NIRS research-grade acquisition system, dedicated to measurements during muscular exercise, is presented. The instrument is able to control up to eight LED sources and two detectors. A digital correlation technique, implemented on a single-chip RISC microcontroller, performs source-to-detector multiplexing. Such algorithm is highly optimized for computational efficiency and ambient noise rejection. Software-configurable input stages allow for flexibility in instrument setup. As a result of the specific correlation technique employed, the instrument is compact, lightweight and efficient. Clinical tests on oxygen consumption show excellent performance

    Obesity Promotes Cooperation of Cancer Stem-Like Cells and Macrophages to Enhance Mammary Tumor Angiogenesis

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    Obesity is correlated with worsened prognosis and treatment resistance in breast cancer. Macrophage-targeted therapies are currently in clinical trials, however, little is known about how obesity may impact treatment efficacy. Within breast adipose tissue, obesity leads to chronic, macrophage-driven inflammation, suggesting that obese breast cancer patients may benefit from these therapies. Using a high fat diet model of obesity, we orthotopically transplanted cancer cell lines into the mammary glands of obese and lean mice. We quantified changes in tumor invasiveness, angiogenesis and metastasis, and examined the efficacy of macrophage depletion to diminish tumor progression in obese and lean mice. Mammary tumors from obese mice grew significantly faster, were enriched for cancer stem-like cells (CSCs) and were more locally invasive and metastatic. Tumor cells isolated from obese mice demonstrated enhanced expression of stem cell-related pathways including Sox2 and Notch2. Despite more rapid growth, mammary tumors from obese mice had reduced necrosis, higher blood vessel density, and greater macrophage recruitment. Depletion of macrophages in obese tumor-bearing mice resulted in increased tumor necrosis, reduced endothelial cells, and enhanced recruitment of CD8+ T cells compared to IgG-treated controls. Macrophages may be an important clinical target to improve treatment options for obese breast cancer patients
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