EVALUATION OF PHYSICOCHEMICAL AND USABLE PROPERTIES OF HAIR SHAMPOOS CONTAINING SUPERCRITICAL CARBON DIOXIDE STRAWBERRY SEED EXTRACT

This paper presents the results of a study of selected physicochemical properties for prototype hair shampoos containing strawberry seed extract obtained under supercritical CO2 conditions. Four formulations were developed and prototypes of hair shampoos were created. It was found that the properties of the shampoos depended on the concentration of the hydrophobic extract used. As a function of the extract concentration, the viscosity of the cosmetic, the foam stability index values and the ability to emulsify fatty soils are lowered. The introduction of the extract into the cosmetic composition resulted in a reduction in the cosmetic lightness and also in a yellow-green color of the shampoo

Smart and Green Buildings Features in the Decision-Making Hierarchy of Office Space Tenants: An Analytic Hierarchy Process Study

In the paper, we investigate the role of smart building or green building innovations on the Polish real estate market using the Analytic Hierarchy Process (AHP) method on the group of experts (consultants, managers, brokers) that are active on the office market in Krakow (study area). The findings point towards the highest relevance of the localisation factor, but also at the relatively low importance of the features of a sustainable building: building automation and information technology systems, as well as energy efficiency or certification. The findings suggest that despite the growing interest in sustainability and technological advancement amongst office market participants in Krakow, the relative importance of smart and green building features in their decision-making processes is relatively low. The study has some interesting practical implications. The knowledge regarding the relative importance of decision criteria can be valuable for developers and investors because the anticipation of tenants’ expectations is directly linked with return on investment and innovation premiums

Smart and Green Buildings Features in the Decision-Making Hierarchy of Office Space Tenants: An Analytic Hierarchy Process Study

In the paper, we investigate the role of smart building or green building innovations on the Polish real estate market using the Analytic Hierarchy Process (AHP) method on the group of experts (consultants, managers, brokers) that are active on the office market in Krakow (study area). The findings point towards the highest relevance of the localisation factor, but also at the relatively low importance of the features of a sustainable building: building automation and information technology systems, as well as energy efficiency or certification. The findings suggest that despite the growing interest in sustainability and technological advancement amongst office market participants in Krakow, the relative importance of smart and green building features in their decision-making processes is relatively low. The study has some interesting practical implications. The knowledge regarding the relative importance of decision criteria can be valuable for developers and investors because the anticipation of tenants’ expectations is directly linked with return on investment and innovation premiums

Is there a bad time for intravenous thrombolysis? The experience of Polish stroke centers

Background and purpose The outcome in acute stroke strongly depends on patient-related issues, as well as on the availability of human and diagnostic resources. Our aim was to evaluate safety and effectiveness of intravenous alteplase for stroke according to the time of admission to the hospital. Materials and methods We analyzed the data of all acute stroke patients treated with alteplase between October 2003 and December 2010, contributed to the Safe Implementation of Thrombolysis for Stroke registry from 27 Polish stroke centers. According to the time of admission we distinguished between: (1) non-working days (Friday 14:30–Monday 08:00 plus national holidays); (2) out-of-office hours (non-working days plus 14:30–08:00 during working days); and (3) night hours (time from 23:00 to 06:00). Patients admitted during regular working hours (Monday 08:00–Friday 14:30, excluding national holidays) were used as the reference. Results Of 1330 patients, 448 (32.5%) were admitted on non-working days, 868 (65.3%) at out-of-office hours, and 105 (7.9%) during night hours. In multivariate logistic regression, none of the evaluated periods showed association with symptomatic intracranial hemorrhage, 7-day mortality, and neurological improvement ≥4 points in the National Institutes of Health Stroke Scale score at day 7. Patients admitted during night hours had lower odds (OR 0.53, 95% CI: 0.29–0.95, p=0.032) for achieving favorable outcome (modified Rankin Scale score 0–2). Conclusions There is no bad time for thrombolysis. Stroke centers should feel confident about the treatment outside regular working hours, irrespective of equipment and staff availability. However, it may be reasonable to pay additional attention during nighttime

Integracja finansowa w Europie po wprowadzeniu euro. Przegląd literatury

The introduction of the euro was one of the most important events in the process of European integration, especially in the financial sector. However, next to its many advantages, the joint currency and single monetary policy increased the probability of property bubbles in the EU low income countries. The excessive speculations, which resulted in the burst of the US property bubble, the financial crisis, as well as the fiscal problems and the recession in Europe in 2010, uncovered the weaknesses of the financial integration and the inability of the European financial system to absorb large shocks. The financial losses, and the risk that some banks and moreover, even some euro zone member countries might become insolvent, underlined the existence of large systemic risks. As a result, cross border lending declined, the European credit market was affected negatively and the uncertainty concerning the stability of the euro increased. The second phase of the crisis in Europe was a starting point to develop some new international solutions to those problems aimed at increasing the stability of the European financial system. Our paper presents an overview of the literature on the advancement of financial integration in the euro zone, as well as in other regions including Poland. The concluding part of this review summarizes also the results of own research of its authors

Integracja finansowa w Europie po wprowadzeniu euro. Przegląd literatury

The introduction of the euro was one of the most important events in the process of European integration, especially in the financial sector. However, next to its many advantages, the joint currency and single monetary policy increased the probability of property bubbles in the EU low income countries. The excessive speculations, which resulted in the burst of the US property bubble, the financial crisis, as well as the fiscal problems and the recession in Europe in 2010, uncovered the weaknesses of the financial integration and the inability of the European financial system to absorb large shocks. The financial losses, and the risk that some banks and moreover, even some euro zone member countries might become insolvent, underlined the existence of large systemic risks. As a result, cross border lending declined, the European credit market was affected negatively and the uncertainty concerning the stability of the euro increased. The second phase of the crisis in Europe was a starting point to develop some new international solutions to those problems aimed at increasing the stability of the European financial system. Our paper presents an overview of the literature on the advancement of financial integration in the euro zone, as well as in other regions including Poland. The concluding part of this review summarizes also the results of own research of its authors

Integracja finansowa w Europie po wprowadzeniu euro. Przegląd literatury

The introduction of the euro was one of the most important events in the process of European integration, especially in the financial sector. However, next to its many advantages, the joint currency and single monetary policy increased the probability of property bubbles in the EU low income countries. The excessive speculations, which resulted in the burst of the US property bubble, the financial crisis, as well as the fiscal problems and the recession in Europe in 2010, uncovered the weaknesses of the financial integration and the inability of the European financial system to absorb large shocks. The financial losses, and the risk that some banks and moreover, even some euro zone member countries might become insolvent, underlined the existence of large systemic risks. As a result, cross border lending declined, the European credit market was affected negatively and the uncertainty concerning the stability of the euro increased. The second phase of the crisis in Europe was a starting point to develop some new international solutions to those problems aimed at increasing the stability of the European financial system. Our paper presents an overview of the literature on the advancement of financial integration in the euro zone, as well as in other regions including Poland. The concluding part of this review summarizes also the results of own research of its authors

Towards property profiling: SYNTHESIS and SAR probing of new tetracyclic diazaphenothiazine analogues

A series of new tertiary phenothiazine derivatives containing a quinoline and a pyridine fragment was synthesized by the reaction of 1-methyl-3-benzoylthio-4-butylthioquinolinium chloride with 3-aminopyridine derivatives bearing various substituents on the pyridine ring. The direction and mechanism of the cyclization reaction of intermediates with the structure of 1-methyl- 4-(3-pyridyl)aminoquinolinium-3-thiolate was related to the substituents in the 2- and 4-pyridine position. The structures of the compounds were analyzed using 1H, 13C NMR (COSY, HSQC, HMBC) and X-ray analysis, respectively. Moreover, the antiproliferative activity against tumor cells (A549, T47D, SNB-19) and a normal cell line (NHDF) was tested. The antibacterial screening of all the compounds was conducted against the reference and quality control strain Staphylococcus aureus ATCC 29213, three clinical isolates of methicillin-resistant S. aureus (MRSA). In silico computation of the intermolecular similarity was performed using principal component analysis (PCA) and hierarchical clustering analysis (HCA) on the pool of structure/property-related descriptors calculated for the novel tetracyclic diazaphenothiazine derivatives. The distance-oriented property evaluation was correlated with the experimental anticancer activities and empirical lipophilicity as well. The quantitative shape-based comparison was conducted using the CoMSA method in order to indicate the potentially valid steric, electronic and lipophilic properties. Finally, the numerical sampling of similarity-related activity landscape (SALI) provided a subtle picture of the SAR trends